PDB: 1738 件ウェブページステータス検索Chemie searchBIRD

---

5OGX	Crystal structure of Amycolatopsis cytochrome P450 reductase GcoB. 分子名称: BROMIDE ION, Cytochrome P450 reductase, FE2/S2 (INORGANIC) CLUSTER, ... 著者 Mallinson, S.J.B, Johnson, C.W, Neidle, E.L, Beckham, G.T, McGeehan, J.E. 登録日 2017-07-13 公開日 2018-07-04 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 A promiscuous cytochrome P450 aromatic O-demethylase for lignin bioconversion. Nat Commun, 9, 2018
3QOA	Crystal structure of a human cytochrome P450 2B6 (Y226H/K262R) in complex with the inhibitor 4-Benzylpyridine. 分子名称: 4-benzylpyridine, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B6, ... 著者 Shah, M.B, Pascual, J, Stout, C.D, Halpert, J.R. 登録日 2011-02-09 公開日 2011-09-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structures of Cytochrome P450 2B6 Bound to 4-Benzylpyridine and 4-(4-Nitrobenzyl)pyridine: Insight into Inhibitor Binding and Rearrangement of Active Site Side Chains. Mol.Pharmacol., 80, 2011
7TLO	X-ray crystal structure of substrate free cytochrome P450 CYP142A3 from Mycobacterium Marinum 分子名称: ACETATE ION, Cytochrome P450 142A3, PROTOPORPHYRIN IX CONTAINING FE 著者 Ghith, A, Bruning, J.B, Bell, S.G. 登録日 2022-01-18 公開日 2022-09-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 The Structures of the Steroid Binding CYP142 Cytochrome P450 Enzymes from Mycobacterium ulcerans and Mycobacterium marinum. Acs Infect Dis., 8, 2022
3QU8	Crystal structure of a human cytochrome P450 2B6 (Y226H/K262R) in complex with the inhibitor 4-(4-Nitrobenzyl)pyridine. 分子名称: 4-(4-nitrobenzyl)pyridine, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B6, ... 著者 Shah, M.B, Pascual, J, Stout, C.D, Halpert, J.R. 登録日 2011-02-23 公開日 2011-09-21 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structures of Cytochrome P450 2B6 Bound to 4-Benzylpyridine and 4-(4-Nitrobenzyl)pyridine: Insight into Inhibitor Binding and Rearrangement of Active Site Side Chains. Mol.Pharmacol., 80, 2011
1GED	A positive charge route for the access of nadh to heme formed in the distal heme pocket of cytochrome p450nor 分子名称: BROMIDE ION, CYTOCHROME P450 55A1, PROTOPORPHYRIN IX CONTAINING FE 著者 Kudo, T, Takaya, N, Park, S.-Y, Shiro, Y, Shoun, H. 登録日 2000-11-02 公開日 2000-11-22 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A positively charged cluster formed in the heme-distal pocket of cytochrome P450nor is essential for interaction with NADH J.Biol.Chem., 276, 2001
1JFB	X-ray structure of nitric oxide reductase (cytochrome P450nor) in the ferric resting state at atomic resolution 分子名称: GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, nitric-oxide reductase cytochrome P450 55A1 著者 Shimizu, H, Adachi, S, Park, S.Y, Shiro, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2001-06-20 公開日 2001-12-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 X-ray structure of nitric oxide reductase (cytochrome P450nor) at atomic resolution. Acta Crystallogr.,Sect.D, 58, 2002
1GEB	X-RAY CRYSTAL STRUCTURE AND CATALYTIC PROPERTIES OF THR252ILE MUTANT OF CYTOCHROME P450CAM 分子名称: CAMPHOR, CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE 著者 Hishiki, T, Shimada, H, Nagano, S, Park, S.-Y, Ishimura, Y. 登録日 2000-11-01 公開日 2000-11-15 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 X-ray crystal structure and catalytic properties of Thr252Ile mutant of cytochrome P450cam: roles of Thr252 and water in the active center. J.Biochem., 128, 2000
1JFC	X-ray structure of nitric oxide reductase (cytochrome P450nor) in the ferrous CO state at atomic resolution 分子名称: CARBON MONOXIDE, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Shimizu, H, Adachi, S, Park, S.Y, Shiro, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2001-06-20 公開日 2001-12-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 X-ray structure of nitric oxide reductase (cytochrome P450nor) at atomic resolution. Acta Crystallogr.,Sect.D, 58, 2002
3P3O	Crystal Structure of the Cytochrome P450 Monooxygenase AurH (ntermII) from Streptomyces Thioluteus 分子名称: CHLORIDE ION, Cytochrome P450, GLYCEROL, ... 著者 Zocher, G, Richter, M.E.A, Mueller, U, Hertweck, C. 登録日 2010-10-05 公開日 2011-02-16 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Structural fine-tuning of a multifunctional cytochrome p450 monooxygenase. J.Am.Chem.Soc., 133, 2011
3P3X	Crystal Structure of the Cytochrome P450 Monooxygenase AurH (nterm-AurH-I) from Streptomyces Thioluteus 分子名称: CHLORIDE ION, Cytochrome P450, GLYCEROL, ... 著者 Zocher, G, Richter, M.E.A, Mueller, U, Hertweck, C. 登録日 2010-10-05 公開日 2011-02-16 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural fine-tuning of a multifunctional cytochrome p450 monooxygenase. J.Am.Chem.Soc., 133, 2011
3P3Z	Crystal Structure of the Cytochrome P450 Monooxygenase AurH from Streptomyces Thioluteus in Complex with Ancymidol 分子名称: (S)-cyclopropyl(4-methoxyphenyl)pyrimidin-5-ylmethanol, CHLORIDE ION, Cytochrome P450, ... 著者 Zocher, G, Richter, M.E.A, Mueller, U, Hertweck, C. 登録日 2010-10-05 公開日 2011-02-16 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural fine-tuning of a multifunctional cytochrome p450 monooxygenase. J.Am.Chem.Soc., 133, 2011
3P3L	Crystal Structure of the Cytochrome P450 monooxygenase AurH (wildtype) from Streptomyces Thioluteus 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, Cytochrome P450, ... 著者 Zocher, G, Richter, M.E.A, Mueller, U, Hertweck, C. 登録日 2010-10-05 公開日 2011-02-16 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural fine-tuning of a multifunctional cytochrome p450 monooxygenase. J.Am.Chem.Soc., 133, 2011
3A1L	Crystal Structure of 11,11'-Dichlorochromopyrrolic Acid Bound Cytochrome P450 StaP (CYP245A1) 分子名称: 3,4-bis(7-chloro-1H-indol-3-yl)-1H-pyrrole-2,5-dicarboxylic acid, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE 著者 Makino, M, Sugimoto, H, Shiro, Y, Asamizu, S, Onaka, H, Nagano, S. 登録日 2009-04-09 公開日 2009-05-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Theoretical and experimental studies of the conversion of chromopyrrolic acid to an antitumor derivative by cytochrome P450 StaP: the catalytic role of water molecules J.Am.Chem.Soc., 131, 2009
4FXB	Crystal structure of CYP105N1 from Streptomyces coelicolor: a cytochrome P450 oxidase in the coelibactin siderophore biosynthetic pathway 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Putative cytochrome P450 著者 Hong, M.K, Lim, Y.R, Kim, J.K, Kim, D.H, Kang, L.W. 登録日 2012-07-03 公開日 2012-11-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal structure of cytochrome P450 CYP105N1 from Streptomyces coelicolor, an oxidase in the coelibactin siderophore biosynthetic pathway Arch.Biochem.Biophys., 528, 2012
2Z3U	Crystal Structure of Chromopyrrolic Acid Bound Cytochrome P450 StaP (CYP245A1) 分子名称: 1,2-ETHANEDIOL, 3,4-DI-1H-INDOL-3-YL-1H-PYRROLE-2,5-DICARBOXYLIC ACID, Cytochrome P450, ... 著者 Makino, M, Sugimoto, H, Shiro, Y, Asamizu, S, Onaka, H, Nagano, S. 登録日 2007-06-06 公開日 2007-07-03 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structures and catalytic mechanism of cytochrome P450 StaP that produces the indolocarbazole skeleton Proc.Natl.Acad.Sci.Usa, 104, 2007
2Z3T	Crystal Structure of Substrate Free Cytochrome P450 StaP (CYP245A1) 分子名称: 1,2-ETHANEDIOL, Cytochrome P450, IMIDAZOLE, ... 著者 Makino, M, Sugimoto, H, Shiro, Y, Asamizu, S, Onaka, H, Nagano, S. 登録日 2007-06-06 公開日 2007-07-03 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structures and catalytic mechanism of cytochrome P450 StaP that produces the indolocarbazole skeleton Proc.Natl.Acad.Sci.Usa, 104, 2007
6BLD	Mycobacterium marinum cytochrome P450 CYP268A2 in complex with pseudoionone 分子名称: (3E,5E)-6,10-dimethylundeca-3,5,9-trien-2-one, Cytochrome P450 268A2 Cyp268A2, PROTOPORPHYRIN IX CONTAINING FE 著者 Child, S.A, Bruning, J.B, Bell, S.G. 登録日 2017-11-09 公開日 2018-01-24 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.997 Å) 主引用文献 Structural and functional characterisation of the cytochrome P450 enzyme CYP268A2 from Biochem. J., 475, 2018
1PKF	Crystal Structure of Epothilone D-bound Cytochrome P450epoK 分子名称: EPOTHILONE D, PROTOPORPHYRIN IX CONTAINING FE, cytochrome p450EpoK 著者 Nagano, S, Li, H, Shimizu, H, Nishida, C, Ogura, H, Ortiz de Montellano, P.R, Poulos, T.L. 登録日 2003-06-05 公開日 2003-10-28 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structures of Epothilone D-bound, Epothilone B-bound, and Substrate-free Forms of Cytochrome P450epoK J.Biol.Chem., 278, 2003
4WNT	Human Cytochrome P450 2D6 Ajmalicine Complex 分子名称: Ajmalicine, Cytochrome P450 2D6, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Wang, A, Stout, C.D, Johnson, E.F. 登録日 2014-10-14 公開日 2015-01-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Contributions of Ionic Interactions and Protein Dynamics to Cytochrome P450 2D6 (CYP2D6) Substrate and Inhibitor Binding. J.Biol.Chem., 290, 2015
7OQ6	Crystal structure of cytochrome P450 Sas16 from Streptomyces asterosporus 分子名称: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, THIOCYANATE ION 著者 Zhang, L, Zhang, S, Bechthold, A, Einsle, O. 登録日 2021-06-02 公開日 2022-06-22 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 P450-mediated dehydrotyrosine formation during WS9326 biosynthesis proceeds via dehydrogenation of a specific acylated dipeptide substrate. Acta Pharm Sin B, 13, 2023
4WNW	Human Cytochrome P450 2D6 Thioridazine Complex 分子名称: 10-{2-[(2R)-1-methylpiperidin-2-yl]ethyl}-2-(methylsulfanyl)-10H-phenothiazine, Cytochrome P450 2D6, NICKEL (II) ION, ... 著者 Wang, A, Stout, C.D, Johnson, E.F. 登録日 2014-10-14 公開日 2015-01-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.299 Å) 主引用文献 Contributions of Ionic Interactions and Protein Dynamics to Cytochrome P450 2D6 (CYP2D6) Substrate and Inhibitor Binding. J.Biol.Chem., 290, 2015
4RUI	Crystal structure of a cytochrome P450 2A6 in complex with a monoterpene - sabinene. 分子名称: Cytochrome P450 2A6, PROTOPORPHYRIN IX CONTAINING FE, Sabinene 著者 Shah, M.B, Stout, C.D, Halpert, J.R. 登録日 2014-11-19 公開日 2015-01-28 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Structural and Biophysical Characterization of Human Cytochromes P450 2B6 and 2A6 Bound to Volatile Hydrocarbons: Analysis and Comparison. Mol.Pharmacol., 87, 2015
6M4P	Cytochrome P450 monooxygenase StvP2 substrate-bound structure 分子名称: 6-methoxy-streptovaricin C, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE 著者 Sun, G, Hu, C, Mei, Q, Luo, M, Chen, X, Li, Z, Liu, Y, Deng, Z, Zhang, Z, Sun, Y. 登録日 2020-03-08 公開日 2020-08-12 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Uncovering the cytochrome P450-catalyzed methylenedioxy bridge formation in streptovaricins biosynthesis. Nat Commun, 11, 2020
6UDL	Structure of Human Cytochrome P450 1A1 with Duocarmycin Prodrug (S) ICT-2700 分子名称: Cytochrome P450 1A1, PROTOPORPHYRIN IX CONTAINING FE, [(1S)-1-(chloromethyl)-1,6-dihydropyrrolo[3,2-e]indol-3(2H)-yl](5-methoxy-1H-indol-2-yl)methanone 著者 Bart, A.G, Scott, E.E. 登録日 2019-09-19 公開日 2020-09-23 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Cytochrome P450 binding and bioactivation of tumor-targeted duocarmycin agents Drug Metab.Dispos., 2021
4PWV	Structure of P450sky (CYP163B3), a cytochrome P450 from skyllamycin biosynthesis in complex with a peptidyl carrier protein domain 分子名称: P450 monooxygenase, PROTOPORPHYRIN IX CONTAINING FE, Peptide synthetase, ... 著者 Haslinger, K, Cryle, M.J. 登録日 2014-03-21 公開日 2014-07-23 最終更新日 2014-08-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The structure of a transient complex of a nonribosomal Peptide synthetase and a cytochrome p450 monooxygenase. Angew.Chem.Int.Ed.Engl., 53, 2014

<234567891011121314151617>