PDB: 392 件ウェブページステータス検索Chemie searchBIRD

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6SHV	T. cruzi FPPS in complex with 5-(4-fluorophenoxy)pyridin-2-amine 分子名称: 5-(4-fluoranylphenoxy)pyridin-2-amine, Farnesyl diphosphate synthase, SULFATE ION, ... 著者 Petrick, J.K, Muenzker, L, Schleberger, C, Cornaciu, I, Clavel, D, Marquez, J.A, Jahnke, W. 登録日 2019-08-08 公開日 2020-08-26 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.808 Å) 主引用文献 Targeting farnesyl pyrophosphate synthase of Trypanosoma cruzi by fragment-based lead discovery Thesis, 2019
5E8H	Crystal structure of geranylfarnesyl pyrophosphate synthases 2 from Arabidopsis thaliana 分子名称: Geranylgeranyl pyrophosphate synthase 3, chloroplastic 著者 Wang, C, Chen, Q, Wang, G, Zhang, P. 登録日 2015-10-14 公開日 2015-11-11 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural Analyses of Short-Chain Prenyltransferases Identify an Evolutionarily Conserved GFPPS Clade in Brassicaceae Plants. Mol Plant, 9, 2016
6T7N	Trypanosoma cruzi farnesyl diphosphate synthase in complex with IPP and Mn 分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Farnesyl diphosphate synthase, MANGANESE (II) ION 著者 Magari, F, Heine, A, Klebe, G. 登録日 2019-10-22 公開日 2020-11-18 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Trypanosoma cruzi farnesyl diphosphate synthase in complex with IPP and Mn To Be Published
5DGM	Crystal structure of human FPPS in complex with monophosphonate compound 7 分子名称: Farnesyl pyrophosphate synthase, PHOSPHATE ION, {2-[(phosphonomethyl)carbamoyl]-1H-benzo[g]indol-1-yl}acetic acid 著者 Rondeau, J.M, Bourgier, E, Lehmann, S. 登録日 2015-08-28 公開日 2016-07-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.86 Å) 主引用文献 A General Strategy for Targeting Drugs to Bone. Angew.Chem.Int.Ed.Engl., 54, 2015
5DIQ	Crystal structure of human FPPS in complex with salicylic acid derivative 3a 分子名称: 2-(naphthalen-1-ylmethoxy)benzoic acid, Farnesyl pyrophosphate synthase, GLYCEROL, ... 著者 Rondeau, J.M, Bourgier, E, Lehmann, S. 登録日 2015-09-01 公開日 2015-09-30 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding. Chemmedchem, 10, 2015
5DJP	Crystal structure of human FPPS in complex with biaryl compound 5 分子名称: 4-(naphthalen-1-yl)-1H-indole-2-carboxylic acid, Farnesyl pyrophosphate synthase, PHOSPHATE ION 著者 Rondeau, J.M, Bourgier, E, Lehmann, S. 登録日 2015-09-02 公開日 2015-09-30 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding. Chemmedchem, 10, 2015
5E8K	Crystal structure of polyprenyl pyrophosphate synthase 2 from Arabidopsis thaliana 分子名称: Geranylgeranyl pyrophosphate synthase 10, mitochondrial 著者 Wang, C, Chen, Q, Fan, D, Li, J, Wang, G, Zhang, P. 登録日 2015-10-14 公開日 2015-11-11 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (3.028 Å) 主引用文献 Structural Analyses of Short-Chain Prenyltransferases Identify an Evolutionarily Conserved GFPPS Clade in Brassicaceae Plants. Mol Plant, 9, 2016
6SXL	Crystal structure of CrtE 分子名称: Geranylgeranyl pyrophosphate synthase, PHOSPHATE ION 著者 Feng, Y, Morgan, R.M.L, Nixon, P.J. 登録日 2019-09-26 公開日 2020-06-24 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structure of Geranylgeranyl Pyrophosphate Synthase (CrtE) Involved in Cyanobacterial Terpenoid Biosynthesis. Front Plant Sci, 11, 2020
5ERO	Crystal structure of elongation domain of Phomopsis amygdali fusicoccadiene synthase complexed with cobalt ions and pamidronate 分子名称: COBALT (II) ION, Fusicoccadiene synthase, PAMIDRONATE 著者 Chen, M, Christianson, D.W. 登録日 2015-11-14 公開日 2016-01-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structure and Function of Fusicoccadiene Synthase, a Hexameric Bifunctional Diterpene Synthase. Acs Chem.Biol., 11, 2016
6SDQ	Trypanosoma cruzi farnesyl diphosphate synthase in complex with fragment 2m5n 分子名称: 2-methoxy-5-nitro-phenol, Farnesyl diphosphate synthase, SULFATE ION, ... 著者 Magari, F, Heine, A, Klebe, G. 登録日 2019-07-29 公開日 2020-08-26 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Trypanosoma cruzi farnesyl diphosphate synthase in complex with fragment 2m5n To Be Published
5E8L	Crystal structure of geranylgeranyl pyrophosphate synthase 11 from Arabidopsis thaliana 分子名称: Heterodimeric geranylgeranyl pyrophosphate synthase large subunit 1, chloroplastic 著者 Wang, C, Chen, Q, Fan, D, Li, J, Wang, G, Zhang, P. 登録日 2015-10-14 公開日 2015-11-11 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.807 Å) 主引用文献 Structural Analyses of Short-Chain Prenyltransferases Identify an Evolutionarily Conserved GFPPS Clade in Brassicaceae Plants. Mol Plant, 9, 2016
5ERN	Crystal structure of elongation domain of Phomopsis amygdali fusicoccadiene synthase 分子名称: Fusicoccadiene synthase 著者 Chen, M, Christianson, D.W. 登録日 2015-11-14 公開日 2016-01-20 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.434 Å) 主引用文献 Structure and Function of Fusicoccadiene Synthase, a Hexameric Bifunctional Diterpene Synthase. Acs Chem.Biol., 11, 2016
5DGS	Crystal structure of human FPPS in complex with the monophosphonate compound 15 分子名称: Farnesyl pyrophosphate synthase, {(E)-2-[6-(acetylamino)-8-(naphthalen-1-yl)quinolin-2-yl]ethenyl}phosphonic acid 著者 Rondeau, J.M, Bourgier, E, Lehmann, S. 登録日 2015-08-28 公開日 2016-07-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 A General Strategy for Targeting Drugs to Bone. Angew.Chem.Int.Ed.Engl., 54, 2015
5CG6	Neutron crystal structure of human farnesyl pyrophosphate synthase in complex with risedronate and isopentenyl pyrophosphate 分子名称: 1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE BIS-PHOSPHONIC ACID, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Farnesyl pyrophosphate synthase, ... 著者 Yokoyama, T, Mizuguchi, M, Ostermann, A, Kusaka, K, Niimura, N, Schrader, T.E, Tanaka, I. 登録日 2015-07-09 公開日 2015-10-14 最終更新日 2024-04-03 実験手法 NEUTRON DIFFRACTION (1.7 Å), X-RAY DIFFRACTION 主引用文献 Protonation State and Hydration of Bisphosphonate Bound to Farnesyl Pyrophosphate Synthase J.Med.Chem., 58, 2015
8A7L	PcIDS1 in complex with Mg2+, GPP, and ZOL 分子名称: GERANYL DIPHOSPHATE, GLYCEROL, Isoprenyl diphosphate synthase, ... 著者 Ecker, F, Boland, W, Groll, M. 登録日 2022-06-21 公開日 2023-05-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Metal-dependent enzyme symmetry guides the biosynthetic flux of terpene precursors. Nat.Chem., 15, 2023
8A7C	PcIDS1 in complex with Mg2+, IPP, and ZOL 分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, GLYCEROL, Isoprenyl diphosphate synthase, ... 著者 Ecker, F, Boland, W, Groll, M. 登録日 2022-06-20 公開日 2023-05-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Metal-dependent enzyme symmetry guides the biosynthetic flux of terpene precursors. Nat.Chem., 15, 2023
8A7K	PcIDS1 in complex with Mg2+/Mn2+, IPP, and ZOL 分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, GLYCEROL, Isoprenyl diphosphate synthase, ... 著者 Ecker, F, Boland, W, Groll, M. 登録日 2022-06-21 公開日 2023-05-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Metal-dependent enzyme symmetry guides the biosynthetic flux of terpene precursors. Nat.Chem., 15, 2023
8A6Z	PcIDS1 in complex with Mn2+ and IPP 分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, GLYCEROL, Isoprenyl diphosphate synthase, ... 著者 Ecker, F, Boland, W, Groll, M. 登録日 2022-06-20 公開日 2023-05-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Metal-dependent enzyme symmetry guides the biosynthetic flux of terpene precursors. Nat.Chem., 15, 2023
8A7U	PcIDS1_F315D in complex with Mg2+ and GPP 分子名称: GERANYL DIPHOSPHATE, GLYCEROL, Isoprenyl diphosphate synthase, ... 著者 Ecker, F, Boland, F, Groll, M. 登録日 2022-06-21 公開日 2023-05-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Metal-dependent enzyme symmetry guides the biosynthetic flux of terpene precursors. Nat.Chem., 15, 2023
8A7R	PcIDS1_I420A in complex with Mg2+ and GPP 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GERANYL DIPHOSPHATE, GLYCEROL, ... 著者 Ecker, F, Boland, W, Groll, M. 登録日 2022-06-21 公開日 2023-05-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Metal-dependent enzyme symmetry guides the biosynthetic flux of terpene precursors. Nat.Chem., 15, 2023
8A7A	PcIDS1 in complex with Mg2+ and 3-Br-GPP 分子名称: Isoprenyl diphosphate synthase, MAGNESIUM ION, [(2Z)-3-bromanyl-7-methyl-octa-2,6-dienyl] phosphono hydrogen phosphate 著者 Ecker, F, Boland, W, Groll, M. 登録日 2022-06-20 公開日 2023-05-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Metal-dependent enzyme symmetry guides the biosynthetic flux of terpene precursors. Nat.Chem., 15, 2023
8A6U	PcIDS1 in complex with Mg2+ 分子名称: Isoprenyl diphosphate synthase, MAGNESIUM ION 著者 Ecker, F, Boland, W, Groll, M. 登録日 2022-06-20 公開日 2023-05-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Metal-dependent enzyme symmetry guides the biosynthetic flux of terpene precursors. Nat.Chem., 15, 2023
8A73	PcIDS1 in complex with Mn2+ and GPP 分子名称: GERANYL DIPHOSPHATE, Isoprenyl diphosphate synthase, MAGNESIUM ION, ... 著者 Ecker, F, Boland, W, Groll, M. 登録日 2022-06-20 公開日 2023-05-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Metal-dependent enzyme symmetry guides the biosynthetic flux of terpene precursors. Nat.Chem., 15, 2023
8A70	PcIDS1 in complex with Mg2+ and GPP 分子名称: GERANYL DIPHOSPHATE, Isoprenyl diphosphate synthase, MAGNESIUM ION 著者 Ecker, F, Boland, W, Groll, M. 登録日 2022-06-20 公開日 2023-05-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Metal-dependent enzyme symmetry guides the biosynthetic flux of terpene precursors. Nat.Chem., 15, 2023
8A6V	PcIDS1 in complex with Mg2+ and IPP 分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Isoprenyl diphosphate synthase, MAGNESIUM ION 著者 Ecker, F, Boland, W, Groll, M. 登録日 2022-06-20 公開日 2023-05-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Metal-dependent enzyme symmetry guides the biosynthetic flux of terpene precursors. Nat.Chem., 15, 2023

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