PDB: 256 件ウェブページステータス検索Chemie searchBIRD

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6HGH	Crystal structure of Alpha1-antichymotrypsin variant NewBG-III: a new binding globulin without any bound ligand 分子名称: Alpha-1-antichymotrypsin, MALONIC ACID, alpha1-Antichymotrypsin 著者 Schmidt, K, Muller, Y.A. 登録日 2018-08-23 公開日 2019-05-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy. J.Struct.Biol., 207, 2019
6HGI	Crystal structure of Alpha1-antichymotrypsin variant NewBG-III: a new binding globulin in complex with corticosterone 分子名称: Alpha-1-antichymotrypsin, CORTICOSTERONE 著者 Schmidt, K, Muller, Y.A. 登録日 2018-08-23 公開日 2019-05-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.517 Å) 主引用文献 NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy. J.Struct.Biol., 207, 2019
1BR8	IMPLICATIONS FOR FUNCTION AND THERAPY OF A 2.9A STRUCTURE OF BINARY-COMPLEXED ANTITHROMBIN 分子名称: PROTEIN (ANTITHROMBIN-III), PROTEIN (PEPTIDE) 著者 Skinner, R, Chang, W.S.W, Jin, L, Pei, X.Y, Huntington, J.A, Abrahams, J.P, Carrell, R.W, Lomas, D.A. 登録日 1998-08-26 公開日 1998-09-02 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Implications for function and therapy of a 2.9 A structure of binary-complexed antithrombin. J.Mol.Biol., 283, 1998
1DVN	LATENT FORM OF PLASMINOGEN ACTIVATOR INHIBITOR-1 (PAI-1) 分子名称: PLASMINOGEN ACTIVATOR INHIBITOR-1 著者 Stout, T.J, Graham, H, Buckley, D.I, Matthews, D.J. 登録日 2000-01-21 公開日 2000-09-13 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structures of active and latent PAI-1: a possible stabilizing role for chloride ions. Biochemistry, 39, 2000
1ATH	THE INTACT AND CLEAVED HUMAN ANTITHROMBIN III COMPLEX AS A MODEL FOR SERPIN-PROTEINASE INTERACTIONS 分子名称: ANTITHROMBIN III 著者 Schreuder, H.A, Hol, W.G.J. 登録日 1993-12-14 公開日 1995-02-07 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 The intact and cleaved human antithrombin III complex as a model for serpin-proteinase interactions. Nat.Struct.Biol., 1, 1994
6I7U	Alpha-1-antitrypsin (Ala250Met) in the native conformation 分子名称: Alpha-1-antitrypsin 著者 Aldobiyan, I, Lomas, D.A, Irving, J.A. 登録日 2018-11-19 公開日 2019-11-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structural determinants of instability in alpha-1-antitrypsin To Be Published
1B3K	Plasminogen activator inhibitor-1 分子名称: PLASMINOGEN ACTIVATOR INHIBITOR-1 著者 Sharp, A.M, Stein, P.E, Pannu, N.S, Read, R.J. 登録日 1998-12-11 公開日 1999-12-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.99 Å) 主引用文献 The active conformation of plasminogen activator inhibitor 1, a target for drugs to control fibrinolysis and cell adhesion. Structure Fold.Des., 7, 1999
1C8O	2.9 A STRUCTURE OF CLEAVED VIRAL SERPIN CRMA 分子名称: ICE INHIBITOR 著者 Simonovic, M, Gettins, P.G.W, Volz, K. 登録日 2000-06-01 公開日 2000-09-06 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal structure of viral serpin crmA provides insights into its mechanism of cysteine proteinase inhibition. Protein Sci., 9, 2000
6I3I	Crystal structure of reactive center loop (RCL) cleaved angiotensinogen 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensinogen 著者 Yan, Y, Read, R.J. 登録日 2018-11-06 公開日 2018-12-26 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.97 Å) 主引用文献 Structural basis for the specificity of renin-mediated angiotensinogen cleavage. J. Biol. Chem., 294, 2019
6I8S	Discovery and characterisation of an antibody that selectively modulates the inhibitory activity of plasminogen activator inhibitor-1 分子名称: HEAVY CHAIN OF FAB FRAGMENT FROM AN PAI-1 ANTIBODY, LIGHT CHAIN OF FAB FRAGMENT FROM AN PAI-1 ANTIBODY, Plasminogen activator inhibitor 1 著者 Vousden, K.A, Lundqvist, T, Popovic, B. 登録日 2018-11-21 公開日 2019-02-13 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Discovery and characterisation of an antibody that selectively modulates the inhibitory activity of plasminogen activator inhibitor-1. Sci Rep, 9, 2019
1E03	PLASMA ALPHA ANTITHROMBIN-III AND PENTASACCHARIDE 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3,4-di-O-methyl-2,6-di-O-sulfo-alpha-D-glucopyranose-(1-4)-2,3-di-O-methyl-beta-D-glucopyranuronic acid-(1-4)-2,3,6-tri-O-sulfo-alpha-D-glucopyranose-(1-4)-3-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2,3,6-tri-O-sulfo-alpha-D-glucopyranoside, ... 著者 McCoy, A.J, Jin, L, Abrahams, J.-P, Skinner, R, Carrell, R.W. 登録日 2000-03-09 公開日 2000-06-02 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure of Beta-Antithrombin and the Effect of Glycosylation on Antithrombin'S Heparin Affinity and Activity. J.Mol.Biol., 326, 2003
1DZH	P14-FLUORESCEIN-N135Q-S380C-ANTITHROMBIN-III 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTITHROMBIN-III, ... 著者 Mccoy, A.J, Huntington, J.A, Carrell, R.W. 登録日 2000-02-28 公開日 2000-05-26 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 The Conformational Activation of Antithrombin. A 2. 85-A Structure of a Fluorescein Derivative Reveals an Electrostatic Link between the Hinge and Heparin Binding Regions. J.Biol.Chem., 275, 2000
1E05	PLASMA ALPHA ANTITHROMBIN-III 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTITHROMBIN-III, ... 著者 McCoy, A.J, Skinner, R, Abrahams, J.-P, Pei, X.Y, Carrell, R.W. 登録日 2000-03-09 公開日 2000-06-02 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Structure of Beta-Antithrombin and the Effect of Glycosylation on Antithrombin'S Heparin Affinity and Activity. J.Mol.Biol., 326, 2003
6I4V	Alpha-1-antitrypsin Queen's (K154N) variant 分子名称: 3-trimethylsilylpropane-1-sulfonic acid, Alpha-1-antitrypsin, GLYCINE 著者 Aldobiyan, I, Lomas, D.A, Irving, J.A. 登録日 2018-11-12 公開日 2019-11-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Structural determinants of instability in alpha-1-antitrypsin To Be Published
1DZG	N135Q-S380C-ANTITHROMBIN-III 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTITHROMBIN-III, ... 著者 McCoy, A.J, Huntington, J.A, Carrell, R.W. 登録日 2000-02-28 公開日 2000-05-26 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 The Conformational Activation of Antithrombin. A 2. 85-A Structure of a Fluorescein Derivative Reveals an Electrostatic Link between the Hinge and Heparin Binding Regions. J.Biol.Chem., 275, 2000
6I3Z	Fab fragment of an antibody selective for wild-type alpha-1-antitrypsin in complex with its antigen 分子名称: Alpha-1-antitrypsin, Fab 2H2 heavy chain, Fab 2H2 light chain, ... 著者 Laffranchi, M, Elliston, E.L.K, Miranda, E, Perez, J, Jagger, A.M, Fra, A, Lomas, D.A, Irving, J.A. 登録日 2018-11-08 公開日 2019-11-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Intrahepatic heteropolymerization of M and Z alpha-1-antitrypsin. JCI Insight, 5, 2020
6IAY	Alpha-1-antitrypsin Queen's (Lys154Asn) variant 分子名称: Alpha-1-antitrypsin, GLYCINE 著者 Aldobiyan, I, Lomas, D.A, Irving, J.A. 登録日 2018-11-28 公開日 2019-12-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural determinants of instability in alpha-1-antitrypsin To Be Published
1E04	PLASMA BETA ANTITHROMBIN-III 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTITHROMBIN-III, GLYCEROL, ... 著者 Mccoy, A.J, Skinner, R, Abrahams, J.-P, Pei, X.Y, Carrell, R.W. 登録日 2000-03-09 公開日 2000-06-02 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of Beta-Antithrombin and the Effect of Glycosylation on Antithrombin'S Heparin Affinity and Activity. J.Mol.Biol., 326, 2003
1DVM	ACTIVE FORM OF HUMAN PAI-1 分子名称: CHLORIDE ION, PLASMINOGEN ACTIVATOR INHIBITOR-1 著者 Stout, T.J, Graham, H, Buckley, D.I, Matthews, D.J. 登録日 2000-01-21 公開日 2000-09-06 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structures of active and latent PAI-1: a possible stabilizing role for chloride ions. Biochemistry, 39, 2000
1DB2	CRYSTAL STRUCTURE OF NATIVE PLASMINOGEN ACTIVATOR INHIBITOR-1 分子名称: PLASMINOGEN ACTIVATOR INHIBITOR-1 著者 Nar, H, Bauer, M, Stassen, J.M, Lang, D, Gils, A, Declerck, P. 登録日 1999-11-02 公開日 1999-11-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Plasminogen activator inhibitor 1. Structure of the native serpin, comparison to its other conformers and implications for serpin inactivation. J.Mol.Biol., 297, 2000
6HGN	Crystal structure of Alpha1-antichymotrypsin variant DBS-II-allo-L55V: an allosterically controlled doxorubicin-binding serpin with an unprecedentedly high ligand release efficacy 分子名称: 1,2-ETHANEDIOL, Alpha-1-antichymotrypsin 著者 Schmidt, K, Muller, Y.A. 登録日 2018-08-23 公開日 2019-05-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.478 Å) 主引用文献 NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy. J.Struct.Biol., 207, 2019
6GWN	Crystal Structure of Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-W175F) in Complex with Two Inhibitory Nanobodies (VHH-2g-42, VHH-2w-64) 分子名称: Plasminogen activator inhibitor 1, VHH-2g-42, VHH-2w-64 著者 Sillen, M, Weeks, S.D, Strelkov, S.V, Declerck, P.J. 登録日 2018-06-25 公開日 2020-01-01 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Molecular mechanism of two nanobodies that inhibit PAI-1 activity reveals a modulation at distinct stages of the PAI-1/plasminogen activator interaction. J.Thromb.Haemost., 18, 2020
6GWP	Crystal Structure of Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-stab) in Complex with Two Inhibitory Nanobodies (VHH-2g-42, VHH-2w-64) 分子名称: Plasminogen Activator Inhibitor-1, VHH-2g-42, VHH-2w-64 著者 Sillen, M, Weeks, S.D, Strelkov, S.V, Declerck, P.J. 登録日 2018-06-25 公開日 2020-01-01 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Molecular mechanism of two nanobodies that inhibit PAI-1 activity reveals a modulation at distinct stages of the PAI-1/plasminogen activator interaction. J.Thromb.Haemost., 18, 2020
1C5G	PLASMINOGEN ACTIVATOR INHIBITOR-1 分子名称: PLASMINOGEN ACTIVATOR INHIBITOR-1 著者 Goldsmith, E.J. 登録日 1999-12-07 公開日 1999-12-17 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Engineering of plasminogen activator inhibitor-1 to reduce the rate of latency transition. Nat.Struct.Biol., 2, 1995
6HGE	Crystal structure of Alpha1-antichymotrypsin variant NewBG-I in the uncleaved S-conformation 分子名称: Alpha-1-antichymotrypsin 著者 Gardill, B.R, Schmidt, K, Muller, Y.A. 登録日 2018-08-23 公開日 2019-05-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy. J.Struct.Biol., 207, 2019

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