PDB: 1712 件ウェブページステータス検索Chemie searchBIRD

---

7CBX	Crystal structure of MAP2K7 complexed with a covalent inhibitor 12 分子名称: 3-(1H-indazol-3-yl)-5-(prop-2-enoylamino)-N-prop-2-ynyl-benzamide, Dual specificity mitogen-activated protein kinase kinase 7, GLYCEROL 著者 Kinoshita, T, Murakawa, Y. 登録日 2020-06-15 公開日 2020-09-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.061 Å) 主引用文献 Structural basis for producing selective MAP2K7 inhibitors. Bioorg.Med.Chem.Lett., 30, 2020
2ZDU	Crystal Structure of human JNK3 complexed with an isoquinolone inhibitor 分子名称: 4-[(4-{[6-bromo-3-(methoxycarbonyl)-1-oxo-4-phenylisoquinolin-2(1H)-yl]methyl}phenyl)amino]-4-oxobutanoic acid, Mitogen-activated protein kinase 10 著者 Sogabe, S, Ohra, T, Itoh, F, Habuka, N, Fujishima, A. 登録日 2007-11-27 公開日 2008-09-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Discovery, synthesis and biological evaluation of isoquinolones as novel and highly selective JNK inhibitors (1) Bioorg.Med.Chem., 16, 2008
2ZV6	Crystal structure of human squamous cell carcinoma antigen 1 分子名称: Serpin B3 著者 Zheng, B, Matoba, Y, Katagiri, C, Hibino, T, Sugiyama, M. 登録日 2008-11-01 公開日 2009-02-24 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of SCCA1 and insight about the interaction with JNK1 Biochem.Biophys.Res.Commun., 380, 2009
7D9M	grass carp interleukin-2 分子名称: Interleukin 著者 Junya, w, Jun, z. 登録日 2020-10-13 公開日 2020-10-28 最終更新日 2020-11-11 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 Structural insights into the co-evolution of IL-2 and its private receptor in fish. Dev.Comp.Immunol., 115, 2020
1BZW	PEANUT LECTIN COMPLEXED WITH C-LACTOSE 分子名称: CALCIUM ION, MANGANESE (II) ION, PROTEIN (PEANUT LECTIN), ... 著者 Ravishankar, R, Surolia, A, Vijayan, M, Lim, S, Kishi, Y. 登録日 1998-11-05 公開日 1998-11-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Preferred Conformation of C-Lactose at the Free and Peanut Lectin Bound States J.Am.Chem.Soc., 120, 1998
4E73	Crystal structure of JNK1beta-JIP in complex with an azaquinolone inhbitor 分子名称: C-Jun-amino-terminal kinase-interacting protein 1, Mitogen-activated protein kinase 8, methyl 3-(4-{[(1R,2S,3S,5S,7s)-5-aminotricyclo[3.3.1.1~3,7~]dec-2-yl]carbamoyl}benzyl)-4-oxo-1-phenyl-1,4-dihydro-1,8-naphthyridine-2-carboxylate 著者 Lukacs, C.M, Janson, C.A. 登録日 2012-03-16 公開日 2013-05-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Identification of an Adamantyl Azaquinolone JNK Selective Inhibitor. ACS Med Chem Lett, 3, 2012
3O17	Crystal Structure of JNK1-alpha1 isoform 分子名称: C-Jun-amino-terminal kinase-interacting protein 1, JIP1, 10MER PEPTIDE, ... 著者 Abad-Zapatero, C. 登録日 2010-07-20 公開日 2011-01-12 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal Structure of JNK1-alpha1 isoform TO BE PUBLISHED
3E7O	Crystal Structure of JNK2 分子名称: Mitogen-activated protein kinase 9, N-{3-[5-(1H-1,2,4-triazol-3-yl)-1H-indazol-3-yl]phenyl}furan-2-carboxamide 著者 Kuglstatter, A, Villasenor, A.G. 登録日 2008-08-18 公開日 2008-09-09 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 The crystal structure of JNK2 reveals conformational flexibility in the MAP kinase insert and indicates its involvement in the regulation of catalytic activity. J.Mol.Biol., 383, 2008
3FAU	Crystal Structure of human small-MutS related domain 分子名称: NEDD4-binding protein 2 著者 Kim, T.G, Kwon, T.H, Ryu, E.K, Min, K, Heo, S.-D, Song, K.M, Jun, W.J, Jung, E. 登録日 2008-11-18 公開日 2009-12-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Strcutral Dynamincs of the Endonuclease Small-MutS Related Domains of BCL3 binding protein To be Published
7UCD	Transcription factor FosB/JunD bZIP domain covalently modified with the cysteine-targeting alpha-haloketone compound Z2159931480 分子名称: 7-acetyl-4-methoxy-1-benzofuran-3(2H)-one, CHLORIDE ION, Protein fosB, ... 著者 Kumar, A, Machius, M.C, Rudenko, G. 登録日 2022-03-16 公開日 2023-01-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.21 Å) 主引用文献 Chemically targeting the redox switch in AP1 transcription factor Delta FOSB. Nucleic Acids Res., 50, 2022
8G2O	Fab structure - Anti-ApoE-7C11 antibody 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, anti-ApoE-7C11 heavy chain, anti-ApoE-7C11 light chain 著者 Marino, C, Arboleda-Velasquez, J.F. 登録日 2023-02-06 公開日 2023-10-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 APOE Christchurch-mimetic therapeutic antibody reduces APOE-mediated toxicity and tau phosphorylation. Alzheimers Dement, 20, 2024
6EJN	The KLC2 TPR domain bound to the JIP3 leucine zipper domain 分子名称: C-Jun-amino-terminal kinase-interacting protein 3, Kinesin light chain 2 著者 Cockburn, J, Hesketh, S.J, Way, M. 登録日 2017-09-22 公開日 2018-09-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Insights into Kinesin-1 Activation from the Crystal Structure of KLC2 Bound to JIP3. Structure, 26, 2018
4PXJ	Crystallographic structure of the LZII fragment (anti-parallel orientation) from JIP3 分子名称: 1,2-ETHANEDIOL, C-Jun-amino-terminal kinase-interacting protein 3, GUANIDINE, ... 著者 Llinas, P, Menetrey, J. 登録日 2014-03-24 公開日 2015-06-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Structure of a truncated form of leucine zipper II of JIP3 reveals an unexpected antiparallel coiled-coil arrangement. Acta Crystallogr F Struct Biol Commun, 72, 2016
6FUZ	Crystal structure of the TPR domain of KLC1 in complex with the C-terminal peptide of JIP1 分子名称: GLYCEROL, Kinesin light chain 1,Kinesin light chain 1,C-Jun-amino-terminal kinase-interacting protein 1, nanobody 著者 Pernigo, S, Dodding, M.P, Steiner, R.A. 登録日 2018-02-28 公開日 2018-05-02 最終更新日 2019-09-18 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis for isoform-specific kinesin-1 recognition of Y-acidic cargo adaptors. Elife, 7, 2018
3V6R	Discovery of potent and selective covalent inhibitors of JNK 分子名称: 4-{[4-(dimethylamino)butanoyl]amino}-N-(3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide, Mitogen-activated protein kinase 10 著者 Park, H, LoGrasso, P.V, Laughlin, J.D. 登録日 2011-12-20 公開日 2012-02-01 最終更新日 2012-07-25 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Discovery of potent and selective covalent inhibitors of JNK. Chem.Biol., 19, 2012
3V6S	Discovery of potent and selective covalent inhibitors of JNK 分子名称: 3-{[4-(dimethylamino)butanoyl]amino}-N-(4-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide, Mitogen-activated protein kinase 10 著者 Park, H, Laughlin, J.D, LoGrasso, P.V. 登録日 2011-12-20 公開日 2012-02-01 最終更新日 2012-07-25 実験手法 X-RAY DIFFRACTION (2.97 Å) 主引用文献 Discovery of potent and selective covalent inhibitors of JNK. Chem.Biol., 19, 2012
8PTK	Composite structure of Dynein-Dynactin-JIP3-LIS1 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ARP1 actin related protein 1 homolog A, ... 著者 Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P. 登録日 2023-07-14 公開日 2024-03-27 最終更新日 2024-04-10 実験手法 ELECTRON MICROSCOPY (10 Å) 主引用文献 Molecular mechanism of dynein-dynactin complex assembly by LIS1. Science, 383, 2024
8PR4	Dynactin pointed end bound to JIP3 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Arp11, C-Jun-amino-terminal kinase-interacting protein 3, ... 著者 Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P. 登録日 2023-07-12 公開日 2024-03-27 最終更新日 2024-04-10 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Molecular mechanism of dynein-dynactin complex assembly by LIS1. Science, 383, 2024
8PR2	Cytoplasmic dynein-1 heavy chain bound to JIP3-LZI 分子名称: C-Jun-amino-terminal kinase-interacting protein 3, Cytoplasmic dynein 1 heavy chain 1, Cytoplasmic dynein 1 intermediate chain 2, ... 著者 Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P. 登録日 2023-07-12 公開日 2024-03-27 最終更新日 2024-04-10 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Molecular mechanism of dynein-dynactin complex assembly by LIS1. Science, 383, 2024
8PR3	Cytoplasmic dynein-1 heavy chain bound to JIP3-RH1 分子名称: C-Jun-amino-terminal kinase-interacting protein 3, Cytoplasmic dynein 1 heavy chain 1, Cytoplasmic dynein 1 intermediate chain 2, ... 著者 Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P. 登録日 2023-07-12 公開日 2024-03-27 最終更新日 2024-04-10 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Molecular mechanism of dynein-dynactin complex assembly by LIS1. Science, 383, 2024
4G1W	Crystal structure of JNK1 in complex with JIP1 peptide and 7-Fluoro-3-[4-(2-hydroxy-ethanesulfonyl)-benzyl]-4-oxo-1-phenyl-1,4-dihydro-quinoline-2-carboxylic acid methyl ester 分子名称: C-Jun-amino-terminal kinase-interacting protein 1, Mitogen-activated protein kinase 8, methyl 7-fluoro-3-{4-[(2-hydroxyethyl)sulfonyl]benzyl}-4-oxo-1-phenyl-1,4-dihydroquinoline-2-carboxylate 著者 Kuglstatter, A, Shao, A. 登録日 2012-07-11 公開日 2013-07-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Crystal structure of JNK1 in complex with JIP1 peptide and inhibitor To be Published
4H36	Crystal Structure of JNK3 in Complex with ATF2 Peptide 分子名称: Cyclic AMP-dependent transcription factor ATF-2, Mitogen-activated protein kinase 10 著者 Nwachukwu, J.C, Laughlin, J.D, Figuera-Losada, M, Cherry, L, Nettles, K.W, LoGrasso, P.V. 登録日 2012-09-13 公開日 2012-11-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural Mechanisms of Allostery and Autoinhibition in JNK Family Kinases. Structure, 20, 2012
4H3B	Crystal Structure of JNK3 in Complex with SAB Peptide 分子名称: Mitogen-activated protein kinase 10, SH3 domain-binding protein 5 著者 Nwachukwu, J.C, Laughlin, J.D, Figuera-Losada, M, Cherry, L, Nettles, K.W, LoGrasso, P.V. 登録日 2012-09-13 公開日 2012-11-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Structural Mechanisms of Allostery and Autoinhibition in JNK Family Kinases. Structure, 20, 2012
5K4C	Structure of eukaryotic translation initiation factor 3 subunit D (eIF3d) cap binding domain from Nasonia vitripennis, Crystal form 2 分子名称: Eukaryotic translation initiation factor 3 subunit D, GLYCEROL 著者 Kranzusch, P.J, Lee, A.S.Y, Doudna, J.A, Cate, J.H.D. 登録日 2016-05-20 公開日 2016-07-27 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.698 Å) 主引用文献 eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation. Nature, 536, 2016
5K4B	Structure of eukaryotic translation initiation factor 3 subunit D (eIF3d) cap binding domain from Nasonia vitripennis, Crystal form 1 分子名称: CHLORIDE ION, Eukaryotic translation initiation factor 3 subunit D 著者 Kranzusch, P.J, Lee, A.S.Y, Doudna, J.A, Cate, J.H.D. 登録日 2016-05-20 公開日 2016-07-27 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.399 Å) 主引用文献 eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation. Nature, 536, 2016

<234567891011121314151617>