PDB: 46006 件ウェブページステータス検索Chemie searchBIRD

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5G4O	Crystal structure of the p53 cancer mutant Y220C in complex with a trifluorinated derivative of the small molecule stabilizer Phikan083 分子名称: CELLULAR TUMOR ANTIGEN P53, N,N-dimethyl-1-[9-(2,2,2-trifluoroethyl)-9H-carbazol-3-yl]methanamine, ZINC ION 著者 Joerger, A.C, Bauer, M, Baud, M.G.J, Spencer, J. 登録日 2016-05-13 公開日 2016-06-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Harnessing Fluorine-Sulfur Contacts and Multipolar Interactions for the Design of P53 Mutant Y220C Rescue Drugs. Acs Chem.Biol., 11, 2016
8FL9	Human nuclear pre-60S ribosomal subunit (State J3) 分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Vanden Broeck, A, Klinge, S. 登録日 2022-12-21 公開日 2023-07-12 最終更新日 2023-07-26 実験手法 ELECTRON MICROSCOPY (2.75 Å) 主引用文献 Principles of human pre-60 S biogenesis. Science, 381, 2023
3RYR	Domain-domain flexibility leads to allostery within the camp receptor protein (CRP) 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator 著者 Knapp, J, White, M.A, Lee, J.C. 登録日 2011-05-11 公開日 2012-05-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Domain-Domain Flexibility Leads to Allostery within the Cam Receptor Protein (Crp) To be Published
8HPO	Cryo-EM structure of a SIN3/HDAC complex from budding yeast 分子名称: Histone deacetylase RPD3, PHOSPHOTHREONINE, POTASSIUM ION, ... 著者 Guo, Z, Zhan, X, Wang, C. 登録日 2022-12-12 公開日 2023-05-03 最終更新日 2023-07-05 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Structure of a SIN3-HDAC complex from budding yeast. Nat.Struct.Mol.Biol., 30, 2023
8OJ8	60S ribosomal subunit bound to the E3-UFM1 complex - state 1 (native) 分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Penchev, I, DaRosa, P.A, Becker, T, Beckmann, R, Kopito, R. 登録日 2023-03-24 公開日 2024-02-21 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER. Nature, 627, 2024
8FLC	Human nuclear pre-60S ribosomal subunit (State K3) 分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Vanden Broeck, A, Klinge, S. 登録日 2022-12-21 公開日 2023-07-12 最終更新日 2023-07-26 実験手法 ELECTRON MICROSCOPY (2.76 Å) 主引用文献 Principles of human pre-60 S biogenesis. Science, 381, 2023
8FLF	Human nuclear pre-60S ribosomal subunit (State L3) 分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Vanden Broeck, A, Klinge, S. 登録日 2022-12-21 公開日 2023-07-12 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.65 Å) 主引用文献 Principles of human pre-60 S biogenesis. Science, 381, 2023
6MWW	LasR LBD:BB0126 complex 分子名称: 4-[3-(methylsulfonyl)phenoxy]-N-[(1R,3R,5R)-2-oxobicyclo[3.1.0]hexan-3-yl]butanamide, Transcriptional regulator LasR 著者 Bassler, B.L, Paczkowski, J.E. 登録日 2018-10-30 公開日 2019-04-03 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor. Acs Chem.Biol., 14, 2019
1S9K	Crystal Structure of Human NFAT1 and Fos-Jun on the IL-2 ARRE1 Site 分子名称: Human IL-2 ARRE1 Promoter Element, Minus Strand, Plus Strand, ... 著者 Wang, D, Stroud, J.C, Chen, L. 登録日 2004-02-04 公開日 2005-06-14 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Crystal Structure of Human NFAT1 and Fos-Jun on the IL-2 ARRE1 Site To be Published
5YWJ	Global regulatory element SarX 分子名称: HTH-type transcriptional regulator SarX 著者 Wang, Q. 登録日 2017-11-29 公開日 2018-12-05 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.102 Å) 主引用文献 Crystal structure of SarX from Staphylococcus aureus To Be Published
6MWL	LasR LBD:mBTL complex 分子名称: 4-(3-bromophenoxy)-N-[(3S)-2-oxothiolan-3-yl]butanamide, Transcriptional regulator LasR 著者 Bassler, B.L, Paczkowski, J.E. 登録日 2018-10-29 公開日 2019-04-03 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor. Acs Chem.Biol., 14, 2019
6MWZ	LasR LBD T75V/Y93F/A127W:BB0126 分子名称: 4-[3-(methylsulfonyl)phenoxy]-N-[(1S,3S,5S)-2-oxobicyclo[3.1.0]hexan-3-yl]butanamide, ALA-HIS-HIS-HIS-HIS-ALA, Transcriptional regulator LasR 著者 Bassler, B.L, Paczkowski, J.E. 登録日 2018-10-30 公開日 2019-04-03 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.657 Å) 主引用文献 An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor. Acs Chem.Biol., 14, 2019
1MP9	TBP from a mesothermophilic archaeon, Sulfolobus acidocaldarius 分子名称: TATA-binding protein 著者 Koike, H, Kawashima-Ohya, Y, Yamasaki, T, Clowney, L, Katsuya, Y, Suzuki, M. 登録日 2002-09-12 公開日 2003-11-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Origins of Protein Stability Revealed by Comparing Crystal Structures of TATA Binding Proteins. Structure, 12, 2004
6MWH	LasR LBD:BB0020 complex 分子名称: 2-(3-bromophenoxy)-N-[(1S,2S,3R,5S)-2-hydroxybicyclo[3.1.0]hexan-3-yl]acetamide, Transcriptional regulator LasR 著者 Bassler, B.L, Paczkowski, J.E. 登録日 2018-10-29 公開日 2019-04-03 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor. Acs Chem.Biol., 14, 2019
7LVK	Cfr-modified 50S subunit from Escherichia coli 分子名称: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... 著者 Stojkovic, V, Myasnikov, A.G, Frost, A, Fujimori, D.G. 登録日 2021-02-25 公開日 2021-12-15 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.2 Å) 主引用文献 Investigating antibiotic resistance of a ribosomal-RNA methylating enzyme through directed evolution To Be Published
3BR2	Crystal Structure of the Complex of Dequalinium Bound to QacR(E120Q), a Mutant of a Multidrug Binding Transcriptional Repressor 分子名称: DEQUALINIUM, HTH-type transcriptional regulator qacR, SULFATE ION 著者 Brooks, B.E. 登録日 2007-12-20 公開日 2008-12-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Formal electrostatic interactions do not govern QacR-cation affinity To be Published
3BR0	Crystal Structure of the Complex of Malachite Green Bound to QacR(E120Q), a Mutant of a Multidrug Binding Transcriptional Repressor 分子名称: HTH-type transcriptional regulator qacR, IMIDAZOLE, MALACHITE GREEN, ... 著者 Brooks, B.E. 登録日 2007-12-20 公開日 2008-12-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Formal electrostatic interactions do not govern QacR-cation affinity To be Published
3BQZ	Crystal Structure of the Complex of Malachite Green Bound to QacR(E90Q), a Mutant of a Multidrug Binding Transcriptional Repressor 分子名称: HTH-type transcriptional regulator qacR, IMIDAZOLE, MALACHITE GREEN, ... 著者 Brooks, B.E. 登録日 2007-12-20 公開日 2008-12-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Formal electrostatic interactions do not govern QacR-cation affinity To be Published
8J1Z	The global structure of pre50S related to DbpA in state3 分子名称: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... 著者 Yu, T, Zeng, F. 登録日 2023-04-13 公開日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 PTC Remodeling in Pre50S Intermediates: Insights into the Role of DEAD-box RNA Helicase DbpA To Be Published
3BR1	Crystal Structure of the Complex of Dequalinium Bound to QacR(E90Q), a Mutant of a Multidrug Binding Transcriptional Repressor 分子名称: DEQUALINIUM, HTH-type transcriptional regulator qacR, SULFATE ION 著者 Brooks, B.E. 登録日 2007-12-20 公開日 2008-12-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.31 Å) 主引用文献 Formal electrostatic interactions do not govern QacR-cation affinity To be Published
3BTC	crystal structure of QacR(E57Q) bound to malachite green 分子名称: HTH-type transcriptional regulator qacR, MALACHITE GREEN, SULFATE ION 著者 Schumacher, M.A, Schuman, J.T, Brennan, R.G. 登録日 2007-12-28 公開日 2008-08-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 QacR-cation recognition is mediated by a redundancy of residues capable of charge neutralization Biochemistry, 47, 2008
3BTJ	crystal structure of QacR(E58Q) bound to dequalinium 分子名称: DEQUALINIUM, HTH-type transcriptional regulator qacR, SULFATE ION 著者 Schumacher, M.A, Schuman, J.T, Brennan, R.G. 登録日 2007-12-28 公開日 2008-08-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.98 Å) 主引用文献 QacR-cation recognition is mediated by a redundancy of residues capable of charge neutralization Biochemistry, 47, 2008
3BR6	Crystal Structure of the Complex of Rhodamine 6G Bound to QacR(E120Q), a Mutant of a Multidrug Binding Transcriptional Repressor 分子名称: HTH-type transcriptional regulator qacR, RHODAMINE 6G, SULFATE ION 著者 Brooks, B.E. 登録日 2007-12-20 公開日 2008-12-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Formal electrostatic interactions do not govern QacR-cation affinity To be Published
3BTL	crystal structure of QacR(E58Q) bound to malachite green 分子名称: HTH-type transcriptional regulator qacR, MALACHITE GREEN, SULFATE ION 著者 Schumacher, M.A, Schuman, J.T, Brennan, R.G. 登録日 2007-12-28 公開日 2008-08-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 QacR-cation recognition is mediated by a redundancy of residues capable of charge neutralization Biochemistry, 47, 2008
3BR5	Crystal Structure of the Complex of Rhodamine 6G Bound to QacR(E90Q), a Mutant of a Multidrug Binding Transcriptional Repressor 分子名称: HTH-type transcriptional regulator qacR, RHODAMINE 6G, SULFATE ION 著者 Brooks, B.E. 登録日 2007-12-20 公開日 2008-12-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Formal electrostatic interactions do not govern QacR-cation affinity To be Published

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