6MWL

LasR LBD:mBTL complex

Summary for 6MWL

Entry DOI	10.2210/pdb6mwl/pdb
Descriptor	Transcriptional regulator LasR, 4-(3-bromophenoxy)-N-[(3S)-2-oxothiolan-3-yl]butanamide (3 entities in total)
Functional Keywords	transcriptional activator, transcription
Biological source	Pseudomonas aeruginosa (strain UCBPP-PA14)
Total number of polymer chains	2
Total formula weight	54011.53
Authors	Bassler, B.L.,Paczkowski, J.E. (deposition date: 2018-10-29, release date: 2019-04-03, Last modification date: 2024-03-13)
Primary citation	Paczkowski, J.E.,McCready, A.R.,Cong, J.P.,Li, Z.,Jeffrey, P.D.,Smith, C.D.,Henke, B.R.,Hughson, F.M.,Bassler, B.L. An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor. Acs Chem.Biol., 14:378-389, 2019 Cited by PubMed: 30763066 DOI: 10.1021/acschembio.8b00971 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation