6MWL

LasR LBD:mBTL complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000976	molecular_function	transcription cis-regulatory region binding
A	0001216	molecular_function	DNA-binding transcription activator activity
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006355	biological_process	regulation of DNA-templated transcription
A	0009372	biological_process	quorum sensing
A	0010468	biological_process	regulation of gene expression
A	0032993	cellular_component	protein-DNA complex
A	0043565	molecular_function	sequence-specific DNA binding
A	0045893	biological_process	positive regulation of DNA-templated transcription
A	0051544	biological_process	positive regulation of elastin biosynthetic process
A	0060310	biological_process	regulation of elastin catabolic process
B	0000976	molecular_function	transcription cis-regulatory region binding
B	0001216	molecular_function	DNA-binding transcription activator activity
B	0003677	molecular_function	DNA binding
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0006355	biological_process	regulation of DNA-templated transcription
B	0009372	biological_process	quorum sensing
B	0010468	biological_process	regulation of gene expression
B	0032993	cellular_component	protein-DNA complex
B	0043565	molecular_function	sequence-specific DNA binding
B	0045893	biological_process	positive regulation of DNA-templated transcription
B	0051544	biological_process	positive regulation of elastin biosynthetic process
B	0060310	biological_process	regulation of elastin catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue K5G A 301

Chain	Residue
A	TYR50
A	TRP54
A	ASP67
A	THR69
A	GLY120
A	ALA121
A	SER123

---

site_id	AC2
Number of Residues	11
Details	binding site for residue K5G B 301

Chain	Residue
B	TYR50
B	TRP54
B	ASP67
B	THR69
B	TRP82
B	TYR87
B	ALA121
B	SER123
B	HOH502
B	GLY32
B	LEU33

---

Functional Information from PROSITE/UniProt

site_id	PS00622
Number of Residues	28
Details	HTH_LUXR_1 LuxR-type HTH domain signature. GktSweISviCnCseaNVnfHmgNIrrK

Chain	Residue	Details
A	GLY185-LYS212

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	38
Details	DNA_BIND: H-T-H motif => ECO:0000255|PROSITE-ProRule:PRU00411

Chain	Residue	Details
A	SER188-GLY207
B	SER188-GLY207

---