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3BR0

Crystal Structure of the Complex of Malachite Green Bound to QacR(E120Q), a Mutant of a Multidrug Binding Transcriptional Repressor

Summary for 3BR0
Entry DOI10.2210/pdb3br0/pdb
Related1JT6 1JTY 1JUP 1JUS 3BQZ 3BR1 3BR2 3BR3 3BR4 3BR5 3BR6
DescriptorHTH-type transcriptional regulator qacR, SULFATE ION, MALACHITE GREEN, ... (5 entities in total)
Functional Keywordsqacr, multidrug resistance, tetr, malachite green, dna-binding, plasmid, repressor, transcription, transcription regulation
Biological sourceStaphylococcus aureus
Total number of polymer chains2
Total formula weight47500.26
Authors
Brooks, B.E. (deposition date: 2007-12-20, release date: 2008-12-23, Last modification date: 2023-08-30)
Primary citationBrooks, B.E.,Hardie, K.M.,Brown, M.H.,Skurray, R.A.,Brennan, R.G.
Formal electrostatic interactions do not govern QacR-cation affinity
To be Published,
Experimental method
X-RAY DIFFRACTION (2.42 Å)
Structure validation

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