3BR0
Crystal Structure of the Complex of Malachite Green Bound to QacR(E120Q), a Mutant of a Multidrug Binding Transcriptional Repressor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B, A | HTH-type transcriptional regulator qacR | polymer | 194 | 22939.9 | 2 | UniProt (P0A0N3) Pfam (PF00440) Pfam (PF08360) In PDB | Staphylococcus aureus | |
2 | B, A | SULFATE ION | non-polymer | 96.1 | 12 | Chemie (SO4) | |||
3 | A | MALACHITE GREEN | non-polymer | 329.5 | 1 | Chemie (MGR) | |||
4 | A | IMIDAZOLE | non-polymer | 69.1 | 2 | Chemie (IMD) | |||
5 | water | water | 18.0 | 83 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 188 (UniProt: P0A0N3)
PDB | External Database | Details |
---|---|---|
Ser 67 | Lys 67 | engineered mutation |
Ala 72 | Cys 72 | engineered mutation |
Gln 120 | Glu 120 | engineered mutation |
Ser 141 | Cys 141 | engineered mutation |
His 189 | - | expression tag |
His 190 | - | expression tag |
His 191 | - | expression tag |
His 192 | - | expression tag |
His 193 | - | expression tag |
His 194 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 45879.9 | |
Non-Polymers* | Number of molecules | 15 |
Total formula weight | 1620.4 | |
All* | Total formula weight | 47500.3 |