6MWZ

LasR LBD T75V/Y93F/A127W:BB0126

Summary for 6MWZ

• Entry DOI: 10.2210/pdb6mwz/pdb
• Descriptor: Transcriptional regulator LasR, ALA-HIS-HIS-HIS-HIS-ALA, 4-[3-(methylsulfonyl)phenoxy]-N-[(1S,3S,5S)-2-oxobicyclo[3.1.0]hexan-3-yl]butanamide, ... (4 entities in total)
• Functional Keywords: transcriptional activator, transcription
• Biological source: Pseudomonas aeruginosa (strain UCBPP-PA14); More
• Total number of polymer chains: 3
• Total formula weight: 54904.94

Authors

Bassler, B.L.,Paczkowski, J.E. (deposition date: 2018-10-30, release date: 2019-04-03, Last modification date: 2024-03-13)

• Primary citation: Paczkowski, J.E.,McCready, A.R.,Cong, J.P.,Li, Z.,Jeffrey, P.D.,Smith, C.D.,Henke, B.R.,Hughson, F.M.,Bassler, B.L.; An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor.; Acs Chem.Biol., 14:378-389, 2019; PubMed: 30763066; DOI: 10.1021/acschembio.8b00971

Experimental method

X-RAY DIFFRACTION (1.657 Å)