crystal structure of QacR(E58Q) bound to malachite green

Summary for 3BTL

Related1jt6 3BT9 3BTC 3BTI 3BTJ 1jup
DescriptorHTH-type transcriptional regulator qacR, SULFATE ION, MALACHITE GREEN (3 entities in total)
Functional Keywordsqacr, multidrug binding, malachite green, dye, dna-binding, plasmid, repressor, transcription, transcription regulation
Biological sourceStaphylococcus aureus
Total number of polymer chains4
Total molecular weight90479.09
Schumacher, M.A.,Schuman, J.T.,Brennan, R.G. (deposition date: 2007-12-28, release date: 2008-08-12, Last modification date: 2011-07-13)
Primary citation
Peters, K.M.,Schuman, J.T.,Skurray, R.A.,Brown, M.H.,Brennan, R.G.,Schumacher, M.A.
QacR-cation recognition is mediated by a redundancy of residues capable of charge neutralization
Biochemistry, 47:8122-8129, 2008
PubMed: 18616285 (PDB entries with the same primary citation)
DOI: 10.1021/bi8008246
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.25624 3.5% 8.1% 3.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-11-25