3BTL

crystal structure of QacR(E58Q) bound to malachite green

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0045892	biological_process	negative regulation of DNA-templated transcription
B	0003677	molecular_function	DNA binding
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0045892	biological_process	negative regulation of DNA-templated transcription
D	0003677	molecular_function	DNA binding
D	0003700	molecular_function	DNA-binding transcription factor activity
D	0045892	biological_process	negative regulation of DNA-templated transcription
E	0003677	molecular_function	DNA binding
E	0003700	molecular_function	DNA-binding transcription factor activity
E	0045892	biological_process	negative regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 299

Chain	Residue
A	LYS4
A	HIS42

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 E 900

Chain	Residue
E	THR24
E	THR25
E	GLY26
E	LYS36

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 D 270

Chain	Residue
D	LYS36
D	THR24
D	GLY26
D	GLU27

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 E 249

Chain	Residue
E	LYS36
E	TYR40
E	THR45
E	LYS46

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 699

Chain	Residue
A	SER35
A	LYS36
A	GLY37
E	LYS60

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 D 999

Chain	Residue
D	TYR20
D	LYS46
D	GLU105
D	TYR106

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 E 399

Chain	Residue
E	LYS12
E	ILE53
E	ILE56
E	GLU57

---

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 E 799

Chain	Residue
A	LYS36
A	TYR40
E	ASN2
E	ASP5
E	LYS6

---

site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 801

Chain	Residue
A	HIS128
A	LYS132

---

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 279

Chain	Residue
A	ASN2
A	LEU3
A	LYS4
A	HIS42

---

site_id	BC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 E 239

Chain	Residue
E	HIS128
E	LYS132

---

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 D 779

Chain	Residue
D	GLU13
D	ILE16
D	LYS17
D	LYS30

---

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 431

Chain	Residue
A	GLU57
A	TRP61
A	GLN64
A	TYR93

---

site_id	BC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 D 432

Chain	Residue
D	THR23
D	THR24
D	THR25
D	LYS46

---

site_id	BC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 433

Chain	Residue
A	ILE16
A	LYS17
A	PRO94
A	ASN97

---

site_id	BC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE SO4 D 434

Chain	Residue
D	ILE16

---

site_id	BC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MGR A 200

Chain	Residue
A	TRP61
A	GLU90
A	TYR103
A	GLU120
A	ILE124
A	ALA153
A	ASN154
A	ASN157

---

Functional Information from PROSITE/UniProt

site_id	PS01081
Number of Residues	31
Details	HTH_TETR_1 TetR-type HTH domain signature. GYnatTTgeIvklseSSkGnLYyHFkTKen.L

Chain	Residue	Details
B	GLY19-LEU49

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	76
Details	DNA_BIND: H-T-H motif => ECO:0000255|PROSITE-ProRule:PRU00335

Chain	Residue	Details
D	THR24-PHE43
A	THR24-PHE43
E	THR24-PHE43
B	THR24-PHE43

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