1JUP

Crystal structure of the multidrug binding transcriptional repressor QacR bound to malachite green

Summary for 1JUP

Entry DOI	10.2210/pdb1jup/pdb
Related	1JT0 1JT6 1JTX 1JTY 1JUM 1JUS
Descriptor	HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION, SULFATE ION, MALACHITE GREEN, ... (4 entities in total)
Functional Keywords	multidrug recognition, malachite green, qacr, multidrug binding protein, transcription
Biological source	Staphylococcus aureus
Total number of polymer chains	4
Total formula weight	94374.94
Authors	Schumacher, M.A.,Miller, M.C.,Grkovic, S.,Brown, M.H.,Skurray, R.A.,Brennan, R.G. (deposition date: 2001-08-24, release date: 2001-12-12, Last modification date: 2023-08-16)
Primary citation	Schumacher, M.A.,Miller, M.C.,Grkovic, S.,Brown, M.H.,Skurray, R.A.,Brennan, R.G. Structural mechanisms of QacR induction and multidrug recognition. Science, 294:2158-2163, 2001 Cited by PubMed: 11739955 DOI: 10.1126/science.1066020 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.95 Å)

Structure validation