1JUM
Crystal structure of the multidrug binding transcriptional repressor QacR bound to the natural drug berberine
Summary for 1JUM
Entry DOI | 10.2210/pdb1jum/pdb |
Related | 1JT0 1JT6 1JTX 1JTY 1JUP 1JUS |
Descriptor | HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION, SULFATE ION, BERBERINE, ... (4 entities in total) |
Functional Keywords | multidrug binding, berberine, plant alkaloid, natural drug, qacr, multidrug recognition, s. aureus, transcription |
Biological source | Staphylococcus aureus |
Total number of polymer chains | 4 |
Total formula weight | 94381.84 |
Authors | Schumacher, M.A.,Miller, M.C.,Grkovic, S.,Brown, M.H.,Skurray, R.A.,Brennan, R.G. (deposition date: 2001-08-24, release date: 2001-12-12, Last modification date: 2023-08-16) |
Primary citation | Schumacher, M.A.,Miller, M.C.,Grkovic, S.,Brown, M.H.,Skurray, R.A.,Brennan, R.G. Structural mechanisms of QacR induction and multidrug recognition. Science, 294:2158-2163, 2001 Cited by PubMed: 11739955DOI: 10.1126/science.1066020 PDB entries with the same primary citation |
Experimental method |
Structure validation
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