5MRR
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![BU of 5mrr by Molmil](/molmil-images/mine/5mrr) | Crystal structure of L1 protease of Lysobacter sp. XL1 | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GLYCEROL, ... | 著者 | Gabdulkhakov, A, Tishchenko, S, Lisov, A, Leontievsky, A. | 登録日 | 2016-12-26 | 公開日 | 2018-01-17 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Crystal structure of L1 protease of Lysobacter sp. XL1 To Be Published
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3BIU
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![BU of 3biu by Molmil](/molmil-images/mine/3biu) | Human thrombin-in complex with UB-THR10 | 分子名称: | (S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclopentylamino)ethanoyl)pyrrolidine-2-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Hirudin, ... | 著者 | Gerlach, C, Smolinski, M, Steuber, H, Sotriffer, C.A, Heine, A, Hangauer, D.G, Klebe, G. | 登録日 | 2007-12-01 | 公開日 | 2007-12-25 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Thermodynamic Inhibition Profile of a Cyclopentyl and a Cyclohexyl Derivative towards Thrombin: The Same but for Different Reasons Angew.Chem.Int.Ed.Engl., 46, 2007
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4FUB
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![BU of 4fub by Molmil](/molmil-images/mine/4fub) | Crystal Structure of the Urokinase | 分子名称: | 6-[(2S,3S)-3-phenyloxiran-2-yl]naphthalene-2-carboximidamide, ACETATE ION, GLYCEROL, ... | 著者 | Kang, Y.N, Stuckey, J.A, Nienaber, V, Giranda, V. | 登録日 | 2012-06-28 | 公開日 | 2012-08-22 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal Structure of the Urokinase to be published
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4E7N
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![BU of 4e7n by Molmil](/molmil-images/mine/4e7n) | Crystal Structure of AhV_TL-I, a Glycosylated Snake-venom Thrombin-like Enzyme from Agkistrodon halys | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Snake-venom Thrombin-like Enzyme | 著者 | Zeng, F, Li, X, Teng, M, Niu, L. | 登録日 | 2012-03-18 | 公開日 | 2012-04-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Crystal Structure of AhV_TL-I, a Glycosylated Snake-venom Thrombin-like Enzyme from Agkistrodon halys to be published
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5MLS
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![BU of 5mls by Molmil](/molmil-images/mine/5mls) | Thrombin Mutant A190S in complex with (S)-1-(D-phenylalanyl)-N-(3-chlorobenzyl)pyrrolidine-2-carboxamide | 分子名称: | D-phenylalanyl-N-(3-chlorobenzyl)-L-prolinamide, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Marca, A, Sandner, A, Heine, A, Klebe, G. | 登録日 | 2016-12-07 | 公開日 | 2017-12-20 | 最終更新日 | 2018-06-13 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Thrombin Mutante A190S in complex with (S)-1-((R)-2-amino-3,3-diphenylpropanoyl)-N-(4-carbamimidoylbenzyl)pyrrolidine-2-carboxamide to be published
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5O32
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![BU of 5o32 by Molmil](/molmil-images/mine/5o32) | The structure of complement complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Xue, X, Wu, J, Forneris, F, Gros, P. | 登録日 | 2017-05-23 | 公開日 | 2017-06-28 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (4.206209 Å) | 主引用文献 | Regulator-dependent mechanisms of C3b processing by factor I allow differentiation of immune responses. Nat. Struct. Mol. Biol., 24, 2017
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4H42
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![BU of 4h42 by Molmil](/molmil-images/mine/4h42) | Synthesis of a Weak Basic uPA Inhibitor and Crystal Structure of Complex with uPA | 分子名称: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, N-[(2-amino-1,3-benzothiazol-6-yl)carbonyl]glycine, Urokinase-type plasminogen activator | 著者 | Yu, H.-Y, Gao, D, Zhang, X, Jiang, L.-G, Hong, Z.-B, Yuan, C, Fang, X, Wang, J.-D, Huang, M.-D. | 登録日 | 2012-09-14 | 公開日 | 2013-10-30 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Synthesis of a Weak Basic uPA Inhibitor and Crystal Structure of Complex with uPA CHIN.J.STRUCT.CHEM., 32, 2013
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3BIV
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![BU of 3biv by Molmil](/molmil-images/mine/3biv) | Human thrombin-in complex with UB-THR11 | 分子名称: | (S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclohexylamino)ethanoyl)pyrrolidine-2-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Hirudin, ... | 著者 | Gerlach, C, Smolinski, M, Steuber, H, Sotriffer, C.A, Heine, A, Hangauer, D.G, Klebe, G. | 登録日 | 2007-12-01 | 公開日 | 2007-12-25 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Thermodynamic Inhibition Profile of a Cyclopentyl and a Cyclohexyl Derivative towards Thrombin: The Same but for Different Reasons Angew.Chem.Int.Ed.Engl., 46, 2007
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4HTC
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![BU of 4htc by Molmil](/molmil-images/mine/4htc) | THE REFINED STRUCTURE OF THE HIRUDIN-THROMBIN COMPLEX | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), ... | 著者 | Tulinsky, A, Rydel, T.J, Bode, W, Huber, R. | 登録日 | 1993-06-25 | 公開日 | 1994-01-31 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Refined structure of the hirudin-thrombin complex. J.Mol.Biol., 221, 1991
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4E7R
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![BU of 4e7r by Molmil](/molmil-images/mine/4e7r) | Thrombin in complex with 3-amidinophenylalanine inhibitor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[(2S)-3-[4-(2-aminoethyl)piperidin-1-yl]-2-{[(2',4'-dichlorobiphenyl-3-yl)sulfonyl]amino}-3-oxopropyl]benzenecarboximidamide, GLYCEROL, ... | 著者 | Ruehmann, E, Heine, A, Klebe, G. | 登録日 | 2012-03-19 | 公開日 | 2012-06-20 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | New 3-amidinophenylalanine-derived inhibitors of matriptase MEDCHEMCOMM, 3, 2012
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2FXR
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![BU of 2fxr by Molmil](/molmil-images/mine/2fxr) | |
4FUD
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![BU of 4fud by Molmil](/molmil-images/mine/4fud) | Crystal Structure of the Urokinase | 分子名称: | 8-aminonaphthalene-2-carboximidamide, SODIUM ION, SUCCINIC ACID, ... | 著者 | Kang, Y.N, Stuckey, J.A, Nienaber, V, Giranda, V. | 登録日 | 2012-06-28 | 公開日 | 2012-08-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of the Urokinase to be published
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4FU7
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![BU of 4fu7 by Molmil](/molmil-images/mine/4fu7) | Crystal Structure of the Urokinase | 分子名称: | 2-[(7-carbamimidoyl-2-methoxynaphthalen-1-yl)oxy]acetamide, ACETATE ION, SULFATE ION, ... | 著者 | Kang, Y.N, Stuckey, J.A, Nienaber, V, Giranda, V. | 登録日 | 2012-06-28 | 公開日 | 2012-08-22 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of the Urokinase to be published
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4FUE
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![BU of 4fue by Molmil](/molmil-images/mine/4fue) | Crystal Structure of the Urokinase | 分子名称: | 6-(1,2,3,4-tetrahydroisoquinolin-6-ylethynyl)naphthalene-2-carboximidamide, ACETATE ION, GLYCEROL, ... | 著者 | Kang, Y.N, Stuckey, J.A, Nienaber, V, Giranda, V. | 登録日 | 2012-06-28 | 公開日 | 2012-08-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of the Urokinase to be published
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4FUJ
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![BU of 4fuj by Molmil](/molmil-images/mine/4fuj) | Crystal Structure of the Urokinase | 分子名称: | 6-{(E)-2-[3-(2-hydroxyethyl)phenyl]ethenyl}naphthalene-2-carboximidamide, ACETATE ION, GLYCEROL, ... | 著者 | Kang, Y.N, Stuckey, J.A, Nienaber, V, Giranda, V. | 登録日 | 2012-06-28 | 公開日 | 2012-08-22 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Crystal Structure of the Urokinase TO BE PUBLISHED
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4I7Y
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![BU of 4i7y by Molmil](/molmil-images/mine/4i7y) | Crystal Structure of Human Alpha Thrombin in Complex with a 27-mer Aptamer Bound to Exosite II | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, DNA (27-MER), ... | 著者 | Pica, A, Russo Krauss, I, Merlino, A, Mazzarella, L, Sica, F. | 登録日 | 2012-12-01 | 公開日 | 2013-10-16 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Duplex-quadruplex motifs in a peculiar structural organization cooperatively contribute to thrombin binding of a DNA aptamer. Acta Crystallogr.,Sect.D, 69, 2013
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2J4I
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![BU of 2j4i by Molmil](/molmil-images/mine/2j4i) | CRYSTAL STRUCTURE OF A HUMAN FACTOR XA INHIBITOR COMPLEX | 分子名称: | 1-PYRROLIDINEACETAMIDE, 3-[[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]AMINO]-ALPHA-METHYL-N-(1-METHYLETHYL)-N-[2-[(METHYLSULFONYL)AMINO]ETHYL]-2-OXO-, (ALPHAS,3S)-, ... | 著者 | Young, R.J, Campbell, M, Borthwick, A.D, Brown, D, Chan, C, Convery, M.A, Crowe, M.C, Dayal, S, Diallo, H, Kelly, H.A, Paul King, N, Kleanthous, S, Kurtis, C.L, Mason, A.M, Mordaunt, J.E, Patel, C, Pateman, A.J, Senger, S, Shah, G.P, Smith, P.W, Watson, N.S, Weston, H.E, Zhou, P. | 登録日 | 2006-08-31 | 公開日 | 2006-09-27 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure- and Property-Based Design of Factor Xa Inhibitors: Pyrrolidin-2-Ones with Acyclic Alanyl Amides as P4 Motifs. Bioorg.Med.Chem.Lett., 16, 2006
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2J38
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![BU of 2j38 by Molmil](/molmil-images/mine/2j38) | CRYSTAL STRUCTURE OF A HUMAN FACTOR XA INHIBITOR COMPLEX | 分子名称: | 5-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1-BENZOTHIOPHENE-2-SULFONAMIDE, ACTIVATED FACTOR XA HEAVY CHAIN, CALCIUM ION, ... | 著者 | Senger, S, Convery, M.A, Chan, C, Watson, N.S. | 登録日 | 2006-08-18 | 公開日 | 2006-09-27 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Arylsulfonamides: A Study of the Relationship between Activity and Conformational Preferences for a Series of Factor Xa Inhibitors. Bioorg.Med.Chem.Lett., 16, 2006
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7FDW
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![BU of 7fdw by Molmil](/molmil-images/mine/7fdw) | Crystal structure of pepsin cleaved lactoferrin C-lobe at 2.28 A resolution | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ... | 著者 | Singh, P.K, Singh, J, Maurya, A, Sharma, P, Sharma, S, Singh, T.P. | 登録日 | 2021-07-18 | 公開日 | 2021-08-04 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.277 Å) | 主引用文献 | A Peptide Bond from the Inter-lobe Segment in the Bilobal Lactoferrin Acts as a Preferred Site for Cleavage for Serine Proteases to Generate the Perfect C-lobe: Structure of the Pepsin Hydrolyzed Lactoferrin C-lobe at 2.28 angstrom Resolution. Protein J., 40, 2021
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5I4Q
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![BU of 5i4q by Molmil](/molmil-images/mine/5i4q) | Contact-dependent inhibition system from Escherichia coli NC101 - ternary CdiA/CdiI/EF-Tu complex (domains 2 and 3) | 分子名称: | CHLORIDE ION, Contact-dependent inhibitor A, Contact-dependent inhibitor I, ... | 著者 | Michalska, K, Stols, L, Eschenfeldt, W, Hayes, C.S, Goulding, C.W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI) | 登録日 | 2016-02-12 | 公開日 | 2017-06-28 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structure of a novel antibacterial toxin that exploits elongation factor Tu to cleave specific transfer RNAs. Nucleic Acids Res., 45, 2017
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3KHV
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![BU of 3khv by Molmil](/molmil-images/mine/3khv) | Crystal Structures of Urokinase-type Plasminogen Activator in Complex with 4-(Aminomethyl) Benzoic Acid and 4-(Aminomethyl-phenyl)-methanol | 分子名称: | SULFATE ION, TRIETHYLENE GLYCOL, Urokinase-type plasminogen activator, ... | 著者 | Jiang, L.-G, Zhao, G.-X, Bian, X.-B, Yuan, C, Huang, Z.-X, Huang, M.-D. | 登録日 | 2009-10-30 | 公開日 | 2009-12-01 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Crystal Structures of Urokinase-type Plasminogen Activator in Complex with 4-(Aminomethyl) Benzoic Acid and 4-(Aminomethyl-phenyl)-methanol CHIN.J.STRUCT.CHEM., 28, 2009
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3KID
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![BU of 3kid by Molmil](/molmil-images/mine/3kid) | The Crystal Structures of 2-Aminobenzothiazole-based Inhibitors in Complexes with Urokinase-type Plasminogen Activator | 分子名称: | Urokinase-type plasminogen activator, ethyl 2-amino-1,3-benzothiazole-6-carboxylate | 著者 | Jiang, L.-G, Yu, H.Y, Yuan, C, Wang, J.D, Chen, L.Q, Meehan, E.J, Huang, Z.-X, Huang, M.-D. | 登録日 | 2009-11-01 | 公開日 | 2009-12-01 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Crystal Structures of 2-Aminobenzothiazole-based Inhibitors in Complexes with Urokinase-type Plasminogen Activator CHIN.J.STRUCT.CHEM., 28, 2009
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8EPC
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![BU of 8epc by Molmil](/molmil-images/mine/8epc) | |
8EPK
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![BU of 8epk by Molmil](/molmil-images/mine/8epk) | |
8EPH
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![BU of 8eph by Molmil](/molmil-images/mine/8eph) | Crystal structure of human coagulation factor IXa (S195A), apo-form, DES-GLA | 分子名称: | CALCIUM ION, Coagulation factor IXa heavy chain, Coagulation factor IXa light chain, ... | 著者 | Kolyadko, V.N, Krishnaswamy, S. | 登録日 | 2022-10-05 | 公開日 | 2024-07-03 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | An RNA aptamer exploits exosite-dependent allostery to achieve specific inhibition of coagulation factor IXa. Proc.Natl.Acad.Sci.USA, 121, 2024
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