5MLS

Thrombin Mutant A190S in complex with (S)-1-(D-phenylalanyl)-N-(3-chlorobenzyl)pyrrolidine-2-carboxamide

Summary for 5MLS

• Entry DOI: 10.2210/pdb5mls/pdb
• Related PRD ID: PRD_000593
• Descriptor: Thrombin light chain, Thrombin heavy chain, Hirudin variant-2, ... (9 entities in total)
• Functional Keywords: coagulation, blood clotting, convertion of fibrinogen to fibrin, blood clotting inhibitor, preorganization, glycosilation, blood, hydrolase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 36598.87

Authors

Marca, A.,Sandner, A.,Heine, A.,Klebe, G. (deposition date: 2016-12-07, release date: 2017-12-20, Last modification date: 2018-06-13)

• Primary citation: Marca, A.,Sandner, A.,Heine, A.,Klebe, G.; Thrombin Mutante A190S in complex with (S)-1-((R)-2-amino-3,3-diphenylpropanoyl)-N-(4-carbamimidoylbenzyl)pyrrolidine-2-carboxamide; to be published,

Experimental method

X-RAY DIFFRACTION (1.62 Å)