3BIU
Human thrombin-in complex with UB-THR10
Summary for 3BIU
Entry DOI | 10.2210/pdb3biu/pdb |
Related | 1K1O 1K22 1YPG 2ZC9 2ZDA |
Related PRD ID | PRD_000586 |
Descriptor | Thrombin light chain, Thrombin heavy chain, Hirudin, ... (7 entities in total) |
Functional Keywords | serine protease-inhibitor complex, blood clotting, acute phase, blood coagulation, cleavage on pair of basic residues, disease mutation, gamma-carboxyglutamic acid, glycoprotein, kringle, secreted, zymogen, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 35200.10 |
Authors | Gerlach, C.,Smolinski, M.,Steuber, H.,Sotriffer, C.A.,Heine, A.,Hangauer, D.G.,Klebe, G. (deposition date: 2007-12-01, release date: 2007-12-25, Last modification date: 2023-11-15) |
Primary citation | Gerlach, C.,Smolinski, M.,Steuber, H.,Sotriffer, C.A.,Heine, A.,Hangauer, D.G.,Klebe, G. Thermodynamic Inhibition Profile of a Cyclopentyl and a Cyclohexyl Derivative towards Thrombin: The Same but for Different Reasons Angew.Chem.Int.Ed.Engl., 46:8511-8514, 2007 Cited by PubMed: 17902081DOI: 10.1002/anie.200701169 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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