PDB: 48062 件ウェブページステータス検索Chemie searchBIRD

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5K09	Crystal Structure of COMT in complex with a thiazole ligand 分子名称: 5-{3-[(4-methoxyphenyl)methyl]-1H-pyrazol-5-yl}-2,4-dimethyl-1,3-thiazole, Catechol O-methyltransferase, PHOSPHATE ION, ... 著者 Ehler, A, Rodriguez-Sarmiento, R.M, Rudolph, M.G. 登録日 2016-05-17 公開日 2016-09-07 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Design of Potent and Druglike Nonphenolic Inhibitors for Catechol O-Methyltransferase Derived from a Fragment Screening Approach Targeting the S-Adenosyl-l-methionine Pocket. J. Med. Chem., 59, 2016
5JR7	Crystal structure of an ACRDYS heterodimer [RIa(92-365):C] of PKA 分子名称: ADENOSINE-5'-DIPHOSPHATE, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase type I-alpha regulatory subunit 著者 Bruystens, J.G.H, Wu, J, Taylor, S.S. 登録日 2016-05-05 公開日 2017-03-15 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.56 Å) 主引用文献 Structure of a PKA RI alpha Recurrent Acrodysostosis Mutant Explains Defective cAMP-Dependent Activation. J. Mol. Biol., 428, 2016
5JDW	CRYSTAL STRUCTURE OF HUMAN L-ARGININE:GLYCINE AMIDINOTRANSFERASE IN COMPLEX WITH GLYCINE 分子名称: GLYCINE, PROTEIN (L-ARGININE:GLYCINE AMIDINOTRANSFERASE) 著者 Fritsche, E, Humm, A, Huber, R. 登録日 1998-10-07 公開日 1999-02-09 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The ligand-induced structural changes of human L-Arginine:Glycine amidinotransferase. A mutational and crystallographic study. J.Biol.Chem., 274, 1999
5JFK	Crystal structure of a TDR receptor 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Leucine-rich repeat receptor-like protein kinase TDR 著者 Li, Z, Xu, G. 登録日 2016-04-19 公開日 2017-03-29 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.647 Å) 主引用文献 Crystal structure of a TDR receptor To Be Published
5JJ8	Crystal Structure of the Beta Carbonic Anhydrase psCA3 isolated from Pseudomonas aeruginosa - alternate crystal packing form 分子名称: Carbonic anhydrase, ZINC ION 著者 Pinard, M.A, Kurian, J.J, Aggarwal, M, Agbandje-McKenna, M, McKenna, R. 登録日 2016-04-22 公開日 2016-07-06 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.585 Å) 主引用文献 Cryoannealing-induced space-group transition of crystals of the carbonic anhydrase psCA3. Acta Crystallogr.,Sect.F, 72, 2016
5JLS	Crystal Structure of Adhesin competence repressor (AdcR) from Streptococcus pyogenes (C-terminally His tagged) 分子名称: Adhesin competence repressor, ZINC ION 著者 Do, H, Kumaraswami, M. 登録日 2016-04-27 公開日 2017-05-03 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of Adhesin competence repressor (AdcR) from Streptococcus pyogenes To Be Published
5JLW	AntpHD with 15bp DNA duplex R-monothioated at Cytidine-8 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*AP*GP*AP*AP*AP*GP*CP*(C7R)P*AP*TP*TP*AP*GP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*CP*TP*AP*AP*TP*GP*GP*CP*TP*TP*TP*C)-3'), ... 著者 White, M.A, Zandarashvili, L, Iwahara, J, Nguyen, D. 登録日 2016-04-27 公開日 2016-06-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.088 Å) 主引用文献 Stereospecific Effects of Oxygen-to-Sulfur Substitution in DNA Phosphate on Ion Pair Dynamics and Protein-DNA Affinity. Chembiochem, 17, 2016
5J9Q	Crystal structure of the NuA4 core complex 分子名称: Chromatin modification-related protein EAF6, Chromatin modification-related protein YNG2, Enhancer of polycomb-like protein 1, ... 著者 Chen, Z.C, Xu, P. 登録日 2016-04-11 公開日 2016-10-26 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 The NuA4 Core Complex Acetylates Nucleosomal Histone H4 through a Double Recognition Mechanism Mol.Cell, 63, 2016
5JAW	Structure of a beta galactosidase with inhibitor 分子名称: (1S,2S,3S,4S,5R,6R)-5-amino-6-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol, ACETATE ION, Beta-galactosidase, ... 著者 Offen, W, Davies, G. 登録日 2016-04-12 公開日 2017-05-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Towards broad spectrum activity-based glycosidase probes: synthesis and evaluation of deoxygenated cyclophellitol aziridines. Chem. Commun. (Camb.), 53, 2017
5JFI	Crystal structure of a TDIF-TDR complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CLE41, Leucine-rich repeat receptor-like protein kinase TDR 著者 Xu, G, Li, Z. 登録日 2016-04-19 公開日 2017-03-29 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.749 Å) 主引用文献 Crystal structure of a TDIF-TDR complex To Be Published
5JBM	Crystal structgure of Cac1 C-terminus 分子名称: Chromatin assembly factor 1 subunit p90 著者 Churchill, M.E.A, Liu, W, Zhou, Y. 登録日 2016-04-13 公開日 2016-10-26 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The Cac1 subunit of histone chaperone CAF-1 organizes CAF-1-H3/H4 architecture and tetramerizes histones. Elife, 5, 2016
5IZR	Human GIVD cytosolic phospholipase A2 in complex with Methyl gamma-Linolenyl Fluorophosphonate inhibitor and Terbium Chloride 分子名称: Cytosolic phospholipase A2 delta, TERBIUM(III) ION, methyl (R)-(6Z,9Z,12Z)-octadeca-6,9,12-trien-1-ylphosphonofluoridate 著者 Wang, H, Klein, M.G. 登録日 2016-03-25 公開日 2016-06-08 最終更新日 2016-06-22 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 Structure of Human GIVD Cytosolic Phospholipase A2 Reveals Insights into Substrate Recognition. J.Mol.Biol., 428, 2016
5J5P	AMP-PNP-stabilized ATPase domain of topoisomerase IV from Streptococcus pneumoniae, complex type I 分子名称: DNA (5'-D(*GP*CP*GP*CP*GP*C)-3'), DNA topoisomerase 4 subunit B, MAGNESIUM ION, ... 著者 Laponogov, I, Pan, X.-S, Skamrova, G, Umrekar, T, Fisher, L.M, Sanderson, M.R. 登録日 2016-04-03 公開日 2017-07-26 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Trapping of the transport-segment DNA by the ATPase domains of a type II topoisomerase. Nat Commun, 9, 2018
5J5Z	Crystal structure of the D444V disease-causing mutant of the human dihydrolipoamide dehydrogenase 分子名称: Dihydrolipoyl dehydrogenase, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Szabo, E, Mizsei, R, Zambo, Z, Torocsik, B, Weiss, M.S, Adam-Vizi, V, Ambrus, A. 登録日 2016-04-04 公開日 2017-11-15 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Crystal structures of the disease-causing D444V mutant and the relevant wild type human dihydrolipoamide dehydrogenase. Free Radic. Biol. Med., 124, 2018
5JCG	Structure of Human Peroxiredoxin 3 as three stacked rings 分子名称: Thioredoxin-dependent peroxide reductase, mitochondrial 著者 Yewdall, N.A, Gerrard, J.A, Goldstone, D.C. 登録日 2016-04-15 公開日 2016-05-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structures of Human Peroxiredoxin 3 Suggest Self-Chaperoning Assembly that Maintains Catalytic State. Structure, 24, 2016
5JDT	Structure of Spin-labelled T4 lysozyme mutant L118C-R1 at 100K 分子名称: AZIDE ION, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... 著者 Loll, B, Consentius, P, Gohlke, U, Mueller, R, Kaupp, M, Heinemann, U, Wahl, M.C, Risse, T. 登録日 2016-04-17 公開日 2016-09-28 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 Tracking Transient Conformational States of T4 Lysozyme at Room Temperature Combining X-ray Crystallography and Site-Directed Spin Labeling. J.Am.Chem.Soc., 138, 2016
5JZT	Cryo-EM structure of aerolysin pore in LMNG micelle 分子名称: Aerolysin 著者 Iacovache, I, Zuber, B. 登録日 2016-05-17 公開日 2016-07-13 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (7.4 Å) 主引用文献 Cryo-EM structure of aerolysin variants reveals a novel protein fold and the pore-formation process. Nat Commun, 7, 2016
5JXG	Structure of the unliganded form of the proprotein convertase furin. 分子名称: CALCIUM ION, CHLORIDE ION, Furin, ... 著者 Dahms, S.O, Arciniega, M, Steinmetzer, T, Huber, R, Than, M.E. 登録日 2016-05-13 公開日 2016-10-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of the unliganded form of the proprotein convertase furin suggests activation by a substrate-induced mechanism. Proc.Natl.Acad.Sci.USA, 113, 2016
5JZQ	Ultrahigh-resolution centrosymmetric crystal structure of Z-DNA reveals massive presence of multiple conformations 分子名称: DNA (5'-D(*CP*GP*CP*GP*CP*G)-3'), MAGNESIUM ION 著者 Drozdzal, P, Gilski, M, Jaskolski, M. 登録日 2016-05-17 公開日 2016-11-09 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (0.78 Å) 主引用文献 Ultrahigh-resolution centrosymmetric crystal structure of Z-DNA reveals the massive presence of alternate conformations. Acta Crystallogr D Struct Biol, 72, 2016
5K0H	Human factor Xa in complex with synthetic inhibitor benzylsulfonyl-dSer(Benzyl)-Gly-4-amidinobenzylamide 分子名称: CALCIUM ION, Coagulation factor X, O-benzyl-N-(benzylsulfonyl)-D-seryl-N-[(4-carbamimidoylphenyl)methyl]glycinamide 著者 Steinmetzer, T. 登録日 2016-05-17 公開日 2016-07-06 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 New substrate analogue inhibitors of factor Xa containing 4-amidinobenzylamide as P1 residue: part 1. Medicinal Chemistry, 2, 2006
5JZY	Thrombin in complex with (S)-1-((R)-2-amino-3-cyclohexylpropanoyl)-N-(4-carbamimidoylbenzyl)pyrrolidine-2-carboxamide 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-cyclohexyl-D-alanyl-N-[(4-carbamimidoylphenyl)methyl]-L-prolinamide, DIMETHYL SULFOXIDE, ... 著者 Sandner, A, Heine, A, Klebe, G. 登録日 2016-05-17 公開日 2017-06-07 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.27 Å) 主引用文献 Strategies for Late-Stage Optimization: Profiling Thermodynamics by Preorganization and Salt Bridge Shielding. J.Med.Chem., 62, 2019
5K2Y	Crystal structure of M. tuberculosis UspC (monoclinic crystal form) 分子名称: Probable periplasmic sugar-binding lipoprotein UspC 著者 Futterer, K, Fullam, E, Besra, G.S. 登録日 2016-05-19 公開日 2016-06-01 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Structural and functional analysis of the solute-binding protein UspC from Mycobacterium tuberculosis that is specific for amino sugars. Open Biology, 6, 2016
5K7W	Crystal structure of the catalytic domain of Mettl3/Mettl14 complex with SAH 分子名称: N6-adenosine-methyltransferase 70 kDa subunit, N6-adenosine-methyltransferase subunit METTL14, S-ADENOSYL-L-HOMOCYSTEINE 著者 Wang, P, Doxtader, K.A, Nam, Y. 登録日 2016-05-26 公開日 2016-07-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases. Mol.Cell, 63, 2016
5KAH	Crystal structure of a dioxygenase in the Crotonase superfamily in P21, V425T mutant 分子名称: (3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase, [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL (3R)-4-({3-[(2-{[(3,5-DIHYDROXYPHENYL)ACETYL]AMINO}ETHYL)AMINO]-3-OXOPROPYL}AMINO)-3-HYDROXY-2,2-DIMETHYL-4-OXOBUTYL DIHYDROGEN DIPHOSPHATE 著者 Li, K, Fielding, E.N, Condurso, H.L, Bruner, S.D. 登録日 2016-06-01 公開日 2017-06-21 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.779 Å) 主引用文献 Probing the structural basis of oxygen binding in a cofactor-independent dioxygenase. Acta Crystallogr D Struct Biol, 73, 2017
5KBT	Cryo-EM structure of GluA2-1xSTZ complex at 6.4 Angstrom resolution 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2,Voltage-dependent calcium channel gamma-2 subunit, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid 著者 Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I. 登録日 2016-06-03 公開日 2016-07-13 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (6.4 Å) 主引用文献 Elucidation of AMPA receptor-stargazin complexes by cryo-electron microscopy. Science, 353, 2016

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