1ZP4
| Glu28Gln mutant of E. coli Methylenetetrahydrofolate Reductase (oxidized) complex with Methyltetrahydrofolate | 分子名称: | 5,10-methylenetetrahydrofolate reductase, 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Pejchal, R, Sargeant, R, Ludwig, M.L. | 登録日 | 2005-05-16 | 公開日 | 2005-08-09 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structures of NADH and CH(3)-H(4)Folate Complexes of Escherichia coli Methylenetetrahydrofolate Reductase Reveal a Spartan Strategy for a Ping-Pong Reaction Biochemistry, 44, 2005
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1V7W
| Crystal structure of Vibrio proteolyticus chitobiose phosphorylase in complex with GlcNAc | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Hidaka, M, Honda, Y, Nirasawa, S, Kitaoka, M, Hayashi, K, Wakagi, T, Shoun, H, Fushinobu, S. | 登録日 | 2003-12-24 | 公開日 | 2004-06-22 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Chitobiose phosphorylase from Vibrio proteolyticus, a member of glycosyl transferase family 36, has a clan GH-L-like (alpha/alpha)(6) barrel fold. Structure, 12, 2004
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1USR
| Newcastle disease virus hemagglutinin-neuraminidase: Evidence for a second sialic acid binding site and implications for fusion | 分子名称: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 2-acetamido-2-deoxy-alpha-D-glucopyranose, CALCIUM ION, ... | 著者 | Zaitsev, V, Von Itzstein, M, Groves, D, Kiefel, M, Takimoto, T, Portner, A, Taylor, G. | 登録日 | 2003-11-28 | 公開日 | 2004-01-02 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Second Sialic Acid Binding Site in Newcastle Disease Virus Hemagglutinin-Neuraminidase: Implications for Fusion J.Virol., 78, 2004
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1V9P
| Crystal Structure Of Nad+-Dependent DNA Ligase | 分子名称: | ADENOSINE MONOPHOSPHATE, DNA ligase, ZINC ION | 著者 | Lee, J.Y, Chang, C, Song, H.K, Moon, J, Yang, J.K, Kim, H.K, Kwon, S.K, Suh, S.W. | 登録日 | 2004-01-27 | 公開日 | 2004-03-30 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure of NAD(+)-dependent DNA ligase: modular architecture and functional implications. Embo J., 19, 2000
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1UU0
| Histidinol-phosphate aminotransferase (HisC) from Thermotoga maritima (Apo-form) | 分子名称: | HISTIDINOL-PHOSPHATE AMINOTRANSFERASE, PHOSPHATE ION | 著者 | Vega, M.C, Fernandez, F.J, Lehmann, F, Wilmanns, M. | 登録日 | 2003-12-12 | 公開日 | 2004-05-13 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Structural Studies of the Catalytic Reaction Pathway of a Hyperthermophilic Histidinol-Phosphate Aminotransferase J.Biol.Chem., 279, 2004
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2AG9
| Crystal Structure of the Y137S mutant of GM2-Activator Protein | 分子名称: | Ganglioside GM2 activator, ISOPROPYL ALCOHOL, MYRISTIC ACID | 著者 | Wright, C.S, Mi, L.Z, Lee, S, Rastinejad, F. | 登録日 | 2005-07-26 | 公開日 | 2005-10-25 | 最終更新日 | 2024-10-30 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity. Biochemistry, 44, 2005
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1YUY
| HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE GENOTYPE 2a | 分子名称: | RNA-Dependent RNA polymerase, SULFATE ION | 著者 | Biswal, B.K, Cherney, M.M, Wang, M, Chan, L, Yannopoulos, C.G, Bilimoria, D, Nicolas, O, Bedard, J, James, M.N.G. | 登録日 | 2005-02-14 | 公開日 | 2005-03-22 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structures of the RNA dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors. J.Biol.Chem., 280, 2005
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2AGQ
| Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 5'-D(*GP*GP*CP*TP*AP*CP*AP*GP*GP*AP*CP*TP*(DOC))-3', 5'-D(*TP*CP*AP*TP*GP*AP*GP*TP*CP*CP*TP*GP*TP*AP*GP*CP*C)-3', ... | 著者 | Ling, H, Yang, W. | 登録日 | 2005-07-27 | 公開日 | 2005-09-06 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis. Embo J., 24, 2005
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1UMF
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1UU2
| Histidinol-phosphate aminotransferase (HisC) from Thermotoga maritima (apo-form) | 分子名称: | 1,2-ETHANEDIOL, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, HISTIDINOL-PHOSPHATE AMINOTRANSFERASE | 著者 | Vega, M.C, Fernandez, F.J, Lehmann, F, Wilmanns, M. | 登録日 | 2003-12-13 | 公開日 | 2004-03-18 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural Studies of the Catalytic Reaction Pathway of a Hyperthermophilic Histidinol-Phosphate Aminotransferase J.Biol.Chem., 279, 2004
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2ARC
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1YW0
| Crystal structure of the tryptophan 2,3-dioxygenase from Xanthomonas campestris. Northeast Structural Genomics Target XcR13. | 分子名称: | MAGNESIUM ION, tryptophan 2,3-dioxygenase | 著者 | Vorobiev, S.M, Abashidze, M, Forouhar, F, Kuzin, A, Xiao, R, Ciano, M, Aton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2005-02-16 | 公開日 | 2005-03-15 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of the tryptophan 2,3-dioxygenase from Xanthomonas campestris. Northeast Structural Genomics Target XcR13. To be Published
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2AS0
| Crystal Structure of PH1915 (APC 5817): A Hypothetical RNA Methyltransferase | 分子名称: | hypothetical protein PH1915 | 著者 | Sun, W, Xu, X, Pavlova, M, Edwards, A.M, Joachimiak, A, Savchenko, A, Christendat, D, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2005-08-22 | 公開日 | 2005-09-20 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The crystal structure of a novel SAM-dependent methyltransferase PH1915 from Pyrococcus horikoshii. Protein Sci., 14, 2005
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2AT1
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1US8
| The Rad50 signature motif: essential to ATP binding and biological function | 分子名称: | DNA DOUBLE-STRAND BREAK REPAIR RAD50 ATPASE | 著者 | Moncalian, G, Lengsfeld, B, Bhaskara, V, Hopfner, K.P, Karcher, A, Alden, E, Tainer, J.A, Paull, T.T. | 登録日 | 2003-11-20 | 公開日 | 2003-11-25 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The Rad50 Signature Motif: Essential to ATP Binding and Biological Function J.Mol.Biol., 335, 2004
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2AQS
| CU/ZN superoxide dismutase from neisseria meningitidis K91E, K94E double mutant | 分子名称: | COPPER (I) ION, COPPER (II) ION, Superoxide dismutase [Cu-Zn], ... | 著者 | DiDonato, M, Kassmann, C.J, Bruns, C.K, Cabelli, D.E, Cao, Z, Tabatabai, L.B, Kroll, J.S, Getzoff, E.D. | 登録日 | 2005-08-18 | 公開日 | 2006-10-31 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | CU/ZN superoxide dismutase from neisseria meningitidis K91E, K94E double mutant To be Published
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1USH
| 5'-NUCLEOTIDASE FROM E. COLI | 分子名称: | 5'-NUCLEOTIDASE, CARBONATE ION, SULFATE ION, ... | 著者 | Knofel, T, Strater, N. | 登録日 | 1998-09-16 | 公開日 | 1999-06-15 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | X-ray structure of the Escherichia coli periplasmic 5'-nucleotidase containing a dimetal catalytic site. Nat.Struct.Biol., 6, 1999
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1UUM
| Rat dihydroorotate dehydrogenase (DHOD)in complex with atovaquone | 分子名称: | 2-[4-(4-CHLOROPHENYL)CYCLOHEXYLIDENE]-3,4-DIHYDROXY-1(2H)-NAPHTHALENONE, DIHYDROOROTATE DEHYDROGENASE, FLAVIN MONONUCLEOTIDE, ... | 著者 | Hansen, M, Le Nours, J, Johansson, E, Antal, T, Ullrich, A, Loffler, M, Larsen, S. | 登録日 | 2004-01-06 | 公開日 | 2004-04-01 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Inhibitor Binding in a Class 2 Dihydroorotate Dehydrogenase Causes Variations in the Membrane-Associated N-Terminal Domain Protein Sci., 13, 2004
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1Z37
| Crystal structure of Trichomonas vaginalis purine nucleoside phosphorylase complexed with adenosine | 分子名称: | ADENOSINE, purine nucleoside phosphorylase | 著者 | Zhang, Y, Wang, W.H, Wu, S.W, Wang, C.C, Ealick, S.E. | 登録日 | 2005-03-10 | 公開日 | 2005-03-29 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Identification of a subversive substrate of Trichomonas vaginalis purine nucleoside phosphorylase and the crystal structure of the enzyme-substrate complex. J.Biol.Chem., 280, 2005
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1UX6
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2ARS
| Crystal structure of lipoate-protein ligase A From Thermoplasma acidophilum | 分子名称: | Lipoate-protein ligase A, MAGNESIUM ION | 著者 | Kim, D.J, Kim, K.H, Lee, H.H, Lee, S.J, Ha, J.Y, Yoon, H.J, Suh, S.W. | 登録日 | 2005-08-22 | 公開日 | 2005-10-04 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Crystal structure of lipoate-protein ligase A bound with the activated intermediate: insights into interaction with lipoyl domains J.Biol.Chem., 280, 2005
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1UZJ
| Integrin binding cbEGF22-TB4-cbEGF33 fragment of human fibrillin-1, holo form. | 分子名称: | CALCIUM ION, FIBRILLIN-1 | 著者 | Lee, S.S.J, Knott, V, Harlos, K, Handford, P.A, Stuart, D.I. | 登録日 | 2004-03-12 | 公開日 | 2004-04-08 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structure of the Integrin Binding Fragment from Fibrillin-1 Gives New Insights Into Microfibril Organization Structure, 12, 2004
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1ZKN
| Structure of PDE4D2-IBMX | 分子名称: | 3-ISOBUTYL-1-METHYLXANTHINE, MAGNESIUM ION, ZINC ION, ... | 著者 | Huai, Q, Liu, Y, Francis, S.H, Corbin, J.D, Ke, H. | 登録日 | 2005-05-03 | 公開日 | 2005-05-17 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structures of Phosphodiesterases 4 and 5 in Complex with Inhibitor 3-Isobutyl-1-Methylxanthine Suggest a Conformation Determinant of Inhibitor Selectivity J.Biol.Chem., 279, 2004
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2AWC
| deoxy-DcrH-Hr | 分子名称: | MU-OXO-DIIRON, hemerythrin-like domain protein DcrH | 著者 | Isaza, C.E, Silaghi-Dumitrescu, R, Iyer, R.B, Kurtz, D.M, Chan, M.K. | 登録日 | 2005-08-31 | 公開日 | 2006-08-15 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural Basis for O(2) Sensing by the Hemerythrin-like Domain of a Bacterial Chemotaxis Protein: Substrate Tunnel and Fluxional N Terminus Biochemistry, 45, 2006
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1UZF
| Complex of the anti-hypertensive drug captopril an the human testicular angiotensin I-converting enzyme | 分子名称: | 1-(3-MERCAPTO-2-METHYL-PROPIONYL)-PYRROLIDINE-2-CARBOXYLIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ANGIOTENSIN CONVERTING ENZYME, ... | 著者 | Natesh, R, Schwager, S.L.U, Evans, H.R, Sturrock, E.D, Acharya, K.R. | 登録日 | 2004-03-11 | 公開日 | 2004-07-16 | 最終更新日 | 2024-10-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural Details on the Binding of Antihypertensive Drugs Captopril and Enalaprilat to Human Testicular Angiotensin I-Converting Enzyme Biochemistry, 43, 2004
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