1USR

Newcastle disease virus hemagglutinin-neuraminidase: Evidence for a second sialic acid binding site and implications for fusion

Summary for 1USR

• Entry DOI: 10.2210/pdb1usr/pdb
• Related: 1USX
• Descriptor: HEMAGGLUTININ-NEURAMINIDASE GLYCOPROTEIN, N-acetyl-alpha-neuraminic acid-(2-6)-methyl 6-thio-beta-D-galactopyranoside, 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, ... (7 entities in total)
• Functional Keywords: hydrolase, sialidase, neuraminidase, hemagglutinin-neuraminidase, hemagglutinin, glycoprotein
• Biological source: NEWCASTLE DISEASE VIRUS
• Total number of polymer chains: 2
• Total formula weight: 101629.68

Authors

Zaitsev, V.,Von Itzstein, M.,Groves, D.,Kiefel, M.,Takimoto, T.,Portner, A.,Taylor, G. (deposition date: 2003-11-28, release date: 2004-01-02, Last modification date: 2023-12-13)

• Primary citation: Zaitsev, V.,Von Itzstein, M.,Groves, D.,Kiefel, M.,Takimoto, T.,Portner, A.,Taylor, G.; Second Sialic Acid Binding Site in Newcastle Disease Virus Hemagglutinin-Neuraminidase: Implications for Fusion; J.Virol., 78:3733-, 2004; PubMed: 15016893; DOI: 10.1128/JVI.78.7.3733-3741.2004

Experimental method

X-RAY DIFFRACTION (2 Å)