1UUM

Rat dihydroorotate dehydrogenase (DHOD)in complex with atovaquone

Summary for 1UUM

Entry DOI	10.2210/pdb1uum/pdb
Related	1UUO
Descriptor	DIHYDROOROTATE DEHYDROGENASE, FLAVIN MONONUCLEOTIDE, OROTIC ACID, ... (6 entities in total)
Functional Keywords	oxidoreductase, dihydroorotate dehydrogenase, brequinar, atovaquone, nucleotide metabolism, pyrimidine biosynthesis, fad, flavoprotein, transit peptide
Biological source	RATTUS RATTUS (BLACK RAT, ROOF RAT)
Total number of polymer chains	2
Total formula weight	83225.05
Authors	Hansen, M.,Le Nours, J.,Johansson, E.,Antal, T.,Ullrich, A.,Loffler, M.,Larsen, S. (deposition date: 2004-01-06, release date: 2004-04-01, Last modification date: 2024-05-08)
Primary citation	Hansen, M.,Le Nours, J.,Johansson, E.,Antal, T.,Ullrich, A.,Loffler, M.,Larsen, S. Inhibitor Binding in a Class 2 Dihydroorotate Dehydrogenase Causes Variations in the Membrane-Associated N-Terminal Domain Protein Sci., 13:1031-, 2004 Cited by PubMed: 15044733 DOI: 10.1110/PS.03533004 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation