7S1G
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![BU of 7s1g by Molmil](/molmil-images/mine/7s1g) | wild-type Escherichia coli stalled ribosome with antibiotic linezolid | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Young, I.D, Stojkovic, V, Tsai, K, Lee, D.J, Fraser, J.S, Galonic Fujimori, D. | 登録日 | 2021-09-02 | 公開日 | 2021-11-17 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.48 Å) | 主引用文献 | Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics. Nat.Struct.Mol.Biol., 29, 2022
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7S1H
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![BU of 7s1h by Molmil](/molmil-images/mine/7s1h) | Wild-type Escherichia coli ribosome with antibiotic linezolid | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Young, I.D, Stojkovic, V, Tsai, K, Lee, D.J, Fraser, J.S, Galonic Fujimori, D. | 登録日 | 2021-09-02 | 公開日 | 2021-11-17 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.35 Å) | 主引用文献 | Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics. Nat.Struct.Mol.Biol., 29, 2022
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6Y0G
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![BU of 6y0g by Molmil](/molmil-images/mine/6y0g) | Structure of human ribosome in classical-PRE state | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... | 著者 | Bhaskar, V, Schenk, A.D, Cavadini, S, von Loeffelholz, O, Natchiar, S.K, Klaholz, B.P, Chao, J.A. | 登録日 | 2020-02-07 | 公開日 | 2020-04-15 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes. Cell Rep, 31, 2020
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7S1K
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![BU of 7s1k by Molmil](/molmil-images/mine/7s1k) | Cfr-modified Escherichia coli stalled ribosome with antibiotic radezolid | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Tsai, K, Stojkovic, V, Lee, D.J, Young, I.D, Szal, T, Vazquez-Laslop, N, Mankin, A.S, Fraser, J.S, Galonic Fujimori, D. | 登録日 | 2021-09-02 | 公開日 | 2022-01-19 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.42 Å) | 主引用文献 | Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics. Nat.Struct.Mol.Biol., 29, 2022
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8I0V
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![BU of 8i0v by Molmil](/molmil-images/mine/8i0v) | The cryo-EM structure of human post-Bact complex | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ... | 著者 | Zhan, X, Lu, Y, Shi, Y. | 登録日 | 2023-01-11 | 公開日 | 2024-07-31 | 最終更新日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
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8I0W
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![BU of 8i0w by Molmil](/molmil-images/mine/8i0w) | The cryo-EM structure of human C complex | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Coiled-coil domain-containing protein 94, ... | 著者 | Zhan, X, Lu, Y, Shi, Y. | 登録日 | 2023-01-11 | 公開日 | 2024-07-31 | 最終更新日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
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8I0U
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![BU of 8i0u by Molmil](/molmil-images/mine/8i0u) | The cryo-EM structure of human Bact-IV complex | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ... | 著者 | Zhan, X, Lu, Y, Shi, Y. | 登録日 | 2023-01-11 | 公開日 | 2024-07-31 | 最終更新日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
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8I0T
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![BU of 8i0t by Molmil](/molmil-images/mine/8i0t) | The cryo-EM structure of human Bact-III complex | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ... | 著者 | Zhan, X, Lu, Y, Shi, Y. | 登録日 | 2023-01-11 | 公開日 | 2024-07-31 | 最終更新日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
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8P53
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![BU of 8p53 by Molmil](/molmil-images/mine/8p53) | |
7SA4
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![BU of 7sa4 by Molmil](/molmil-images/mine/7sa4) | Damaged 70S ribosome with PrfH bound | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Tian, Y, Zeng, F, Raybarman, A, Carruthers, A, Li, Q, Fatma, S, Huang, R.H. | 登録日 | 2021-09-22 | 公開日 | 2022-08-03 | 実験手法 | ELECTRON MICROSCOPY (2.55 Å) | 主引用文献 | Sequential rescue and repair of stalled and damaged ribosome by bacterial PrfH and RtcB. Proc.Natl.Acad.Sci.USA, 119, 2022
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1Q07
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![BU of 1q07 by Molmil](/molmil-images/mine/1q07) | Crystal structure of the Au(I) form of E. coli CueR, a copper efflux regulator | 分子名称: | GOLD ION, Transcriptional regulator cueR | 著者 | Changela, A, Chen, K, Xue, Y, Holschen, J, Outten, C.E, O'Halloran, T.V, Mondragon, A. | 登録日 | 2003-07-15 | 公開日 | 2003-09-16 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Molecular basis of metal-ion selectivity and zeptomolar sensitivity by CueR Science, 301, 2003
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5LKS
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![BU of 5lks by Molmil](/molmil-images/mine/5lks) | Structure-function insights reveal the human ribosome as a cancer target for antibiotics | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... | 著者 | Myasnikov, A.G, Natchiar, S.K, Nebout, M, Hazemann, I, Imbert, V, Khatter, H, Peyron, J.-F, Klaholz, B.P. | 登録日 | 2016-07-23 | 公開日 | 2017-04-26 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structure-function insights reveal the human ribosome as a cancer target for antibiotics. Nat Commun, 7, 2016
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1ON1
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![BU of 1on1 by Molmil](/molmil-images/mine/1on1) | Bacillus Subtilis Manganese Transport Regulator (Mntr) Bound To Manganese, AB Conformation. | 分子名称: | MANGANESE (II) ION, Transcriptional regulator mntR | 著者 | Glasfeld, A, Guedon, E, Helmann, J.D, Brennan, R.G. | 登録日 | 2003-02-26 | 公開日 | 2003-07-15 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structure of the Manganese-Bound Manganese Transport Regulator of Bacillus subtilis Nat.Struct.Biol., 10, 2003
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7ODE
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![BU of 7ode by Molmil](/molmil-images/mine/7ode) | |
5W62
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![BU of 5w62 by Molmil](/molmil-images/mine/5w62) | Crystal structure of mouse BAX monomer | 分子名称: | Apoptosis regulator BAX, SULFATE ION | 著者 | Robin, A.Y, Colman, P.M, Czabotar, P.E, Luo, C.S. | 登録日 | 2017-06-16 | 公開日 | 2018-06-27 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.196 Å) | 主引用文献 | Ensemble Properties of Bax Determine Its Function. Structure, 26, 2018
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5W5X
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![BU of 5w5x by Molmil](/molmil-images/mine/5w5x) | Crystal structure of BAXP168G in complex with an activating antibody | 分子名称: | 1,2-ETHANEDIOL, 3C10 Fab' heavy chain, 3C10 Fab' light chain, ... | 著者 | Robin, A.Y, Colman, P.M, Czabotar, P.E. | 登録日 | 2017-06-16 | 公開日 | 2018-06-27 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.502 Å) | 主引用文献 | Ensemble Properties of Bax Determine Its Function. Structure, 26, 2018
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5EIZ
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![BU of 5eiz by Molmil](/molmil-images/mine/5eiz) | |
5W60
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![BU of 5w60 by Molmil](/molmil-images/mine/5w60) | |
5W61
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![BU of 5w61 by Molmil](/molmil-images/mine/5w61) | |
7OT5
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![BU of 7ot5 by Molmil](/molmil-images/mine/7ot5) | CspA-70 cotranslational folding intermediate 1 | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Agirrezabala, X, Samatova, E, Macher, M, Liutkute, M, Gil-Carton, D, Novacek, J, Valle, M, Rodnina, M.V. | 登録日 | 2021-06-09 | 公開日 | 2022-01-19 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | A switch from alpha-helical to beta-strand conformation during co-translational protein folding. Embo J., 41, 2022
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7ACR
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![BU of 7acr by Molmil](/molmil-images/mine/7acr) | Structure of post-translocated trans-translation complex on E. coli stalled ribosome. | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Guyomar, C, D'Urso, G, Chat, S, Giudice, E, Gillet, R. | 登録日 | 2020-09-11 | 公開日 | 2021-08-18 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | 主引用文献 | Structures of tmRNA and SmpB as they transit through the ribosome. Nat Commun, 12, 2021
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7AC7
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![BU of 7ac7 by Molmil](/molmil-images/mine/7ac7) | Structure of accomodated trans-translation complex on E. Coli stalled ribosome. | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Guyomar, C, D'Urso, G, Chat, S, Giudice, E, Gillet, R. | 登録日 | 2020-09-10 | 公開日 | 2021-08-18 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | 主引用文献 | Structures of tmRNA and SmpB as they transit through the ribosome. Nat Commun, 12, 2021
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8G61
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![BU of 8g61 by Molmil](/molmil-images/mine/8g61) | mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state) | 分子名称: | 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ... | 著者 | Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. | 登録日 | 2023-02-14 | 公開日 | 2023-04-19 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | 主引用文献 | mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
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7ACJ
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![BU of 7acj by Molmil](/molmil-images/mine/7acj) | Structure of translocated trans-translation complex on E. coli stalled ribosome. | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Guyomar, C, D'Urso, G, Chat, S, Giudice, E, Gillet, R. | 登録日 | 2020-09-11 | 公開日 | 2021-08-18 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structures of tmRNA and SmpB as they transit through the ribosome. Nat Commun, 12, 2021
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2X6O
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![BU of 2x6o by Molmil](/molmil-images/mine/2x6o) | Tet Repressor class D in complex with 7-chlor-2-cyano-iso- tetracycline | 分子名称: | (4S,4AS,6S,8AS)-6-[(1S)-7-CHLORO-4-HYDROXY-1-METHYL-3-OXO-1,3-DIHYDRO-2-BENZOFURAN-1-YL]-4-(DIMETHYLAMINO)-3,8A-DIHYDROXY-1,8-DIOXO-1,4,4A,5,6,7,8,8A-OCTAHYDRONAPHTHALENE-2-CARBONITRILE, CHLORIDE ION, TETRACYCLINE REPRESSOR PROTEIN CLASS D | 著者 | Volkers, G, Hinrichs, W. | 登録日 | 2010-02-18 | 公開日 | 2011-03-02 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Recognition of Drug Degradation Products by Target Proteins: Isotetracycline Binding to Tet Repressor. J.Med.Chem., 54, 2011
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