PDB: 8717 件ウェブページステータス検索Chemie searchBIRD

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2ZMI	Crystal Structure of Rat Vitamin D Receptor Bound to Adamantyl Vitamin D Analogs: Structural Basis for Vitamin D Receptor Antagonism and/or Partial Agonism 分子名称: (1R,3R,7E,17beta)-17-{(1S,2E,5R)-5-hydroxy-1-methyl-5-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]pent-2-en-1-yl}-2-methylidene-9,10-secoestra-5,7-diene-1,3-diol, 1,2-ETHANEDIOL, FORMIC ACID, ... 著者 Nakabayashi, M, Yamada, S, Tanaka, T, Igarashi, M, Yoshimoto, N, Ikura, T, Ito, N, Makishima, M, Tokiwa, H, DeLuca, H.F, Shimizu, M. 登録日 2008-04-19 公開日 2008-09-02 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structures of rat vitamin d receptor bound to adamantyl vitamin d analogs: structural basis for vitamin d receptor antagonism and partial agonism J.Med.Chem., 51, 2008
1H3O	Crystal Structure of the Human TAF4-TAF12 (TAFII135-TAFII20) Complex 分子名称: TRANSCRIPTION INITIATION FACTOR TFIID 135 KDA SUBUNIT, TRANSCRIPTION INITIATION FACTOR TFIID 20/15 KDA SUBUNITS 著者 Werten, S, Mitschler, A, Moras, D. 登録日 2002-09-12 公開日 2002-09-26 最終更新日 2019-07-24 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal Structure of a Subcomplex of Human Transcription Factor TFIID Formed by TATA Binding Protein-Associated Factors Htaf4 (Htaf(II)135) and Htaf12 (Htaf(II)20). J.Biol.Chem., 277, 2002
2ZXM	A New Class of Vitamin D Receptor Ligands that Induce Structural Rearrangement of the Ligand-binding Pocket 分子名称: (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R,3S)-3-(2-hydroxyethyl)heptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexane-1,3-diol, Mediator of RNA polymerase II transcription subunit 1, Vitamin D3 receptor 著者 Nakabayashi, M, Ikura, T, Ito, N. 登録日 2009-01-04 公開日 2009-02-17 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 A New Class of Vitamin D Analogues that Induce Structural Rearrangement of the Ligand-Binding Pocket of the Receptor J.Med.Chem., 52, 2009
3A2H	Crystal structure of the rat vitamin D receptor ligand binding domain complexed with TEI-9647 and a synthetic peptide containing the NR2 box of DRIP 205 分子名称: (1S,3R,5Z,7E,20S,23S)-1,3-dihydroxy-23,26-epoxy-9,10-secocholesta-5,7,10,25(27)-tetraen-26-one, Mediator of RNA polymerase II transcription subunit 1 peptide, Vitamin D3 receptor 著者 Kakuda, S, Takimoto-Kamimura, M. 登録日 2009-05-20 公開日 2010-05-26 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis of the histidine-mediated vitamin D receptor agonistic and antagonistic mechanisms of (23S)-25-dehydro-1alpha-hydroxyvitamin D(3)-26,23-lactone Acta Crystallogr.,Sect.D, 66, 2010
3JD7	The novel asymmetric entry intermediate of a picornavirus captured with nanodiscs 分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... 著者 Lee, H, Shingler, K.L, Organtini, L.J, Ashley, R.E, Makhov, A.M, Conway, J.F, Hafenstein, S. 登録日 2016-04-29 公開日 2016-09-14 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 The novel asymmetric entry intermediate of a picornavirus captured with nanodiscs. Sci Adv, 2, 2016
2ZMH	Crystal Structure of Rat Vitamin D Receptor Bound to Adamantyl Vitamin D Analogs: Structural Basis for Vitamin D Receptor Antagonism and/or Partial Agonism 分子名称: (1R,3R,7E,17beta)-17-{(1R,2E,4R)-4-hydroxy-1-methyl-4-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]but-2-en-1-yl}-2-methylidene-9,10-secoestra-5,7-diene-1,3-diol, Mediator of RNA polymerase II transcription subunit 1, Vitamin D3 receptor 著者 Nakabayashi, M, Yamada, S, Tanaka, T, Igarashi, M, Yoshimoto, N, Ikura, T, Ito, N, Makishima, M, Tokiwa, H, DeLuca, H.F, Shimizu, M. 登録日 2008-04-18 公開日 2008-09-02 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structures of rat vitamin d receptor bound to adamantyl vitamin d analogs: structural basis for vitamin d receptor antagonism and partial agonism J.Med.Chem., 51, 2008
2XNF	The Mediator Med25 activator interaction domain: Structure and cooperative binding of VP16 subdomains 分子名称: MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 25 著者 Vojnic, E, Mourao, A, Seizl, M, Simon, B, Wenzeck, L, Lariviere, L, Baumli, S, Meisterernst, M, Sattler, M, Cramer, P. 登録日 2010-08-02 公開日 2011-03-09 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structure and Vp16 Binding of the Mediator Med25 Activator Interaction Domain. Nat.Struct.Mol.Biol., 18, 2011
7AQK	Model of the actin filament Arp2/3 complex branch junction in cells 分子名称: Actin, alpha skeletal muscle, ACTA1, ... 著者 Faessler, F, Dimchev, G, Hodirnau, V.V, Wan, W, Schur, F.K.M. 登録日 2020-10-22 公開日 2020-12-02 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (9 Å) 主引用文献 Cryo-electron tomography structure of Arp2/3 complex in cells reveals new insights into the branch junction. Nat Commun, 11, 2020
1U9B	MURINE/HUMAN UBIQUITIN-CONJUGATING ENZYME UBC9 分子名称: UBIQUITIN-CONJUGATING ENZYME E9 著者 Tong, H, Hateboer, G, Perrakis, A, Bernards, R, Sixma, T.K. 登録日 1997-05-20 公開日 1997-07-07 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of murine/human Ubc9 provides insight into the variability of the ubiquitin-conjugating system. J.Biol.Chem., 272, 1997
1U9A	HUMAN UBIQUITIN-CONJUGATING ENZYME UBC9 分子名称: UBIQUITIN-CONJUGATING ENZYME 著者 Tong, H, Hateboer, G, Perrakis, A, Bernards, R, Sixma, T.K. 登録日 1997-02-11 公開日 1997-05-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of murine/human Ubc9 provides insight into the variability of the ubiquitin-conjugating system. J.Biol.Chem., 272, 1997
2ZXN	A New Class of Vitamin D Receptor Ligands that Induce Structural Rearrangement of the Ligand-binding Pocket 分子名称: (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2S,3S)-3-(2-hydroxyethyl)heptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexane-1,3-diol, Mediator of RNA polymerase II transcription subunit 1, Vitamin D3 receptor 著者 Nakabayashi, M, Ikura, T, Ito, N. 登録日 2009-01-04 公開日 2009-02-17 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A New Class of Vitamin D Analogues that Induce Structural Rearrangement of the Ligand-Binding Pocket of the Receptor J.Med.Chem., 52, 2009
3BHT	Structure of phosphorylated Thr160 CDK2/cyclin A in complex with the inhibitor meriolin 3 分子名称: 4-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine, Cell division protein kinase 2, Cyclin-A2, ... 著者 Echalier, A, Bettayeb, K, Ferandin, Y, Lozach, O, Clement, M, Valette, A, Liger, F, Marquet, B, Morris, J.C, Endicott, J.A, Joseph, B, Meijer, L. 登録日 2007-11-29 公開日 2008-02-12 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Meriolins, a new class of cell death inducing kinase inhibitors with enhanced selectivity for cyclin-dependent kinases Cancer Res., 67, 2007
3BHV	Structure of phosphorylated Thr160 CDK2/cyclin A in complex with the inhibitor variolin B 分子名称: 9-amino-5-(2-aminopyrimidin-4-yl)pyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidin-4-ol, Cell division protein kinase 2, Cyclin-A2, ... 著者 Echalier, A, Bettayeb, K, Ferandin, Y, Lozach, O, Clement, M, Valette, A, Liger, F, Marquet, B, Morris, J.C, Endicott, J.A, Joseph, B, Meijer, L. 登録日 2007-11-29 公開日 2008-02-12 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Meriolins, a new class of cell death inducing kinase inhibitors with enhanced selectivity for cyclin-dependent kinases Cancer Res., 67, 2007
3BHU	Structure of phosphorylated Thr160 CDK2/cyclin A in complex with the inhibitor meriolin 5 分子名称: 4-(4-propoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine, Cell division protein kinase 2, Cyclin-A2, ... 著者 Echalier, A, Bettayeb, K, Ferandin, Y, Lozach, O, Clement, M, Valette, A, Liger, F, Marquet, B, Morris, J.C, Endicott, J.A, Joseph, B, Meijer, L. 登録日 2007-11-29 公開日 2008-02-12 最終更新日 2017-10-25 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Meriolins, a new class of cell death inducing kinase inhibitors with enhanced selectivity for cyclin-dependent kinases Cancer Res., 67, 2007
2ZMJ	Crystal Structure of Rat Vitamin D Receptor Bound to Adamantyl Vitamin D Analogs: Structural Basis for Vitamin D Receptor Antagonism and/or Partial Agonism 分子名称: (1R,3R,7E,17beta)-17-{(1S,2E,5R)-5-hydroxy-1-methyl-6-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]hex-2-en-1-yl}-2-methylidene-9,10-secoestra-5,7-diene-1,3-diol, Mediator of RNA polymerase II transcription subunit 1, Vitamin D3 receptor 著者 Nakabayashi, M, Yamada, S, Tanaka, T, Igarashi, M, Yoshimoto, N, Ikura, T, Ito, N, Makishima, M, Tokiwa, H, DeLuca, H.F, Shimizu, M. 登録日 2008-04-19 公開日 2008-09-02 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Crystal structures of rat vitamin d receptor bound to adamantyl vitamin d analogs: structural basis for vitamin d receptor antagonism and partial agonism J.Med.Chem., 51, 2008
4DU3	RB69 DNA Polymerase Ternary Complex with dDTP Opposite dT with 3-Deaza-adenine at the N-1 Position of Template Strand 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... 著者 Xia, S, Wang, J, Konigsberg, W.H. 登録日 2012-02-21 公開日 2012-05-23 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Probing minor groove hydrogen bonding interactions between RB69 DNA polymerase and DNA. Biochemistry, 51, 2012
4JSY	Structure of Clostridium thermocellum polynucleotide kinase bound to GTP 分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Metallophosphoesterase 著者 Das, U, Wang, L.K, Smith, P, Shuman, S. 登録日 2013-03-22 公開日 2013-08-28 最終更新日 2013-12-18 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Structural and biochemical analysis of the phosphate donor specificity of the polynucleotide kinase component of the bacterial pnkphen1 RNA repair system. Biochemistry, 52, 2013
2G4C	Crystal Structure of human DNA polymerase gamma accessory subunit 分子名称: DNA polymerase gamma subunit 2 著者 Fan, L, Farr, C.L, Kaguni, L.S, Tainer, J.A. 登録日 2006-02-22 公開日 2006-04-18 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 A novel processive mechanism for DNA synthesis revealed by structure, modeling and mutagenesis of the accessory subunit of human mitochondrial DNA polymerase J.Mol.Biol., 358, 2006
4JT2	Structure of Clostridium thermocellum polynucleotide kinase bound to CTP 分子名称: CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Metallophosphoesterase 著者 Das, U, Wang, L.K, Smith, P, Shuman, S. 登録日 2013-03-22 公開日 2013-08-28 最終更新日 2013-12-18 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Structural and biochemical analysis of the phosphate donor specificity of the polynucleotide kinase component of the bacterial pnkphen1 RNA repair system. Biochemistry, 52, 2013
4JST	Structure of Clostridium thermocellum polynucleotide kinase bound to UTP 分子名称: MAGNESIUM ION, Metallophosphoesterase, SODIUM ION, ... 著者 Das, U, Wang, L.K, Smith, P, Shuman, S. 登録日 2013-03-22 公開日 2013-08-28 最終更新日 2013-12-18 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Structural and biochemical analysis of the phosphate donor specificity of the polynucleotide kinase component of the bacterial pnkphen1 RNA repair system. Biochemistry, 52, 2013
4JT4	Structure of Clostridium thermocellum polynucleotide kinase bound to dATP 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, Metallophosphoesterase, ... 著者 Das, U, Wang, L.K, Smith, P, Shuman, S. 登録日 2013-03-22 公開日 2013-08-28 最終更新日 2013-12-18 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Structural and biochemical analysis of the phosphate donor specificity of the polynucleotide kinase component of the bacterial pnkphen1 RNA repair system. Biochemistry, 52, 2013
2B0U	The Structure of the Follistatin:Activin Complex 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Follistatin, IRIDIUM (III) ION, ... 著者 Thompson, T.B, Lerch, T.F, Cook, R.W, Woodruff, T.K, Jardetzky, T.S. 登録日 2005-09-14 公開日 2005-10-11 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 The Structure of the Follistatin:Activin Complex Reveals Antagonism of Both Type I and Type II Receptor Binding. Dev.Cell, 9, 2005
5MGQ	Solution structure of oxidized and amidated human IAPP (1-37), the diabetes II peptide. 分子名称: Islet amyloid polypeptide 著者 Rodriguez Camargo, D.C, Tripsianes, K, Reif, B. 登録日 2016-11-21 公開日 2017-03-29 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 The redox environment triggers conformational changes and aggregation of hIAPP in Type II Diabetes. Sci Rep, 7, 2017
2I53	Crystal structure of Cyclin K 分子名称: ACETATE ION, Cyclin K 著者 Baek, K, Brown, R.S, Birrane, G, Ladias, J.A.A. 登録日 2006-08-23 公開日 2007-01-02 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal Structure of Human Cyclin K, a Positive Regulator of Cyclin-dependent Kinase 9. J.Mol.Biol., 366, 2007
2K0N	Solution Structure of Yeast Gal11p kix domain 分子名称: Mediator of RNA polymerase II transcription subunit 15 著者 Arthanari, H, Frueh, D.P, Wagner, G.K, Naar, A.M. 登録日 2008-02-04 公開日 2008-03-25 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 A nuclear receptor-like pathway regulating multidrug resistance in fungi. Nature, 452, 2008

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