3A2H
Crystal structure of the rat vitamin D receptor ligand binding domain complexed with TEI-9647 and a synthetic peptide containing the NR2 box of DRIP 205
Summary for 3A2H
Entry DOI | 10.2210/pdb3a2h/pdb |
Related | 3A2I 3A2J |
Descriptor | Vitamin D3 receptor, Mediator of RNA polymerase II transcription subunit 1 peptide, (1S,3R,5Z,7E,20S,23S)-1,3-dihydroxy-23,26-epoxy-9,10-secocholesta-5,7,10,25(27)-tetraen-26-one, ... (4 entities in total) |
Functional Keywords | hormone/growth factor receptor, dna-binding, metal-binding, nucleus, phosphoprotein, transcription, transcription regulation, zinc-finger, activator, receptor, hormone receptor |
Biological source | Rattus norvegicus (Rat) More |
Cellular location | Nucleus: P13053 Q15648 |
Total number of polymer chains | 2 |
Total formula weight | 32052.98 |
Authors | Kakuda, S.,Takimoto-Kamimura, M. (deposition date: 2009-05-20, release date: 2010-05-26, Last modification date: 2023-11-01) |
Primary citation | Kakuda, S.,Ishizuka, S.,Eguchi, H.,Mizwicki, M.T.,Norman, A.W.,Takimoto-Kamimura, M. Structural basis of the histidine-mediated vitamin D receptor agonistic and antagonistic mechanisms of (23S)-25-dehydro-1alpha-hydroxyvitamin D(3)-26,23-lactone Acta Crystallogr.,Sect.D, 66:918-926, 2010 Cited by PubMed: 20693691DOI: 10.1107/S0907444910020810 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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