3JD7

The novel asymmetric entry intermediate of a picornavirus captured with nanodiscs

Summary for 3JD7

• Entry DOI: 10.2210/pdb3jd7/pdb
• EMDB information: 6636 6637 6638
• Descriptor: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... (5 entities in total)
• Functional Keywords: picornavirus, entry intermediate, virus
• Biological source: Coxsackievirus B3; More
• Cellular location: Capsid protein VP0: Virion . Capsid protein VP4: Virion . Capsid protein VP2: Virion . Capsid protein VP3: Virion . Capsid protein VP1: Virion . Protein 2B: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 2C: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3A: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3AB: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Viral protein genome-linked: Virion . Protease 3C: Host cytoplasm . Protein 3CD: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . RNA-directed RNA polymerase: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side : Q66282 Q66282 Q66282 Q66282
• Total number of polymer chains: 4
• Total formula weight: 94091.83

Authors

Lee, H.,Shingler, K.L.,Organtini, L.J.,Ashley, R.E.,Makhov, A.M.,Conway, J.F.,Hafenstein, S. (deposition date: 2016-04-29, release date: 2016-09-14, Last modification date: 2024-02-21)

• Primary citation: Lee, H.,Shingler, K.L.,Organtini, L.J.,Ashley, R.E.,Makhov, A.M.,Conway, J.F.,Hafenstein, S.; The novel asymmetric entry intermediate of a picornavirus captured with nanodiscs.; Sci Adv, 2:e1501929-e1501929, 2016; PubMed: 27574701; DOI: 10.1126/sciadv.1501929

Experimental method

ELECTRON MICROSCOPY (3.9 Å)