6WPQ
 
 | | GNYNVF from hnRNPA2-low complexity domain segment, residues 286-291, D290V variant | | 分子名称: | Heterogeneous nuclear ribonucleoprotein A2 | | 著者 | Lu, J, Cao, Q, Hughes, M.P, Sawaya, M.R, Boyer, D.R, Cascio, D, Eisenberg, D.S. | | 登録日 | 2020-04-27 | | 公開日 | 2020-08-19 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | CryoEM structure of the low-complexity domain of hnRNPA2 and its conversion to pathogenic amyloid.
Nat Commun, 11, 2020
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2AYP
 | | Crystal Structure of CHK1 with an Indol Inhibitor | | 分子名称: | (3Z)-6-(4-HYDROXY-3-METHOXYPHENYL)-3-(1H-PYRROL-2-YLMETHYLENE)-1,3-DIHYDRO-2H-INDOL-2-ONE, Serine/threonine-protein kinase Chk1 | | 著者 | Lin, N.-H, Xia, P, Kovar, P, Chen, Z, Zhang, H, Rosenberg, S.H, Sham, H.L. | | 登録日 | 2005-09-07 | | 公開日 | 2006-09-12 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Synthesis and biological evaluation of 3-ethylidene-1,3-dihydro-indol-2-ones as novel checkpoint 1 inhibitors
Bioorg.Med.Chem.Lett., 16, 2006
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6DWM
 | | Structure of Human Cytochrome P450 1A1 with Bergamottin | | 分子名称: | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, 4-{[(2E)-3,7-dimethylocta-2,6-dien-1-yl]oxy}-7H-furo[3,2-g][1]benzopyran-7-one, Cytochrome P450 1A1, ... | | 著者 | Bart, A.G, Scott, E.E. | | 登録日 | 2018-06-26 | | 公開日 | 2018-10-03 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Structures of human cytochrome P450 1A1 with bergamottin and erlotinib reveal active-site modifications for binding of diverse ligands.
J. Biol. Chem., 293, 2018
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7KYW
 | | Crystal structure of timothy grass allergen Phl p 12.0101 reveals an unusual profilin dimer | | 分子名称: | CITRIC ACID, Profilin-1 | | 著者 | O'Malley, A, Kapingidza, A.B, Hyduke, N, Dolamore, C, Chruszcz, M. | | 登録日 | 2020-12-09 | | 公開日 | 2021-03-31 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of timothy grass allergen Phl p 12.0101 reveals an unusual profilin dimer.
Acta Biochim.Pol., 68, 2021
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3KVN
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5NUP
 | | Structural basis for maintenance of bacterial outer membrane lipid asymmetry | | 分子名称: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, ABC transporter permease, DODECYL-BETA-D-MALTOSIDE, ... | | 著者 | Abellon-Ruiz, J, Kaptan, S.S, Basle, A, Claudi, B, Bumann, D, Kleinekathofer, U, van den Berg, B. | | 登録日 | 2017-05-01 | | 公開日 | 2017-10-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural basis for maintenance of bacterial outer membrane lipid asymmetry.
Nat Microbiol, 2, 2017
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5NUQ
 | | Structural basis for maintenance of bacterial outer membrane lipid asymmetry | | 分子名称: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, Outer membrane protein F, Probable phospholipid-binding lipoprotein mlaA | | 著者 | Abellon-Ruiz, J, Kaptan, S.S, Basle, A, Claudi, B, Bumann, D, Kleinekathofer, U, van den Berg, B. | | 登録日 | 2017-05-01 | | 公開日 | 2017-10-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis for maintenance of bacterial outer membrane lipid asymmetry.
Nat Microbiol, 2, 2017
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5NUO
 | | Structural basis for maintenance of bacterial outer membrane lipid asymmetry | | 分子名称: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, ABC transporter permease, Outer membrane protein F, ... | | 著者 | Abellon-Ruiz, J, Kaptan, S.S, Basle, A, Claudi, B, Bumann, D, Kleinekathofer, U, van den Berg, B. | | 登録日 | 2017-05-01 | | 公開日 | 2017-10-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis for maintenance of bacterial outer membrane lipid asymmetry.
Nat Microbiol, 2, 2017
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5NUR
 | | Structural basis for maintenance of bacterial outer membrane lipid asymmetry | | 分子名称: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-6)-2-amino-2-deoxy-4-O-phosphono-beta-D-glucopyranose-(1-6)-2-amino-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(3-4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-6)-2-amino-2-deoxy-4-O-phosphono-beta-D-glucopyranose-(1-6)-2-amino-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, ... | | 著者 | Abellon-Ruiz, J, Kaptan, S.S, Basle, A, Claudi, B, Bumann, D, Kleinekathofer, U, van den Berg, B. | | 登録日 | 2017-05-01 | | 公開日 | 2017-10-25 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.29 Å) | | 主引用文献 | Structural basis for maintenance of bacterial outer membrane lipid asymmetry.
Nat Microbiol, 2, 2017
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4V4I
 | | Crystal Structure of a 70S Ribosome-tRNA Complex Reveals Functional Interactions and Rearrangements. | | 分子名称: | 16S SMALL SUBUNIT RIBOSOMAL RNA, 23S LARGE SUBUNIT RIBOSOMAL RNA, 30S ribosomal protein S10, ... | | 著者 | Korostelev, A, Trakhanov, S, Laurberg, M, Noller, H.F. | | 登録日 | 2007-02-15 | | 公開日 | 2014-07-09 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.71 Å) | | 主引用文献 | Crystal Structure of a 70S Ribosome-tRNA Complex Reveals Functional Interactions and Rearrangements
Cell(Cambridge,Mass.), 126, 2006
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4WCE
 | | The crystal structure of the large ribosomal subunit of Staphylococcus aureus | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 23S rRNA, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | 著者 | Eyal, Z, Matzov, D, Krupkin, M, Wekselman, I, Zimmerman, E, Rozenberg, H, Bashan, A, Yonath, A. | | 登録日 | 2014-09-04 | | 公開日 | 2015-10-21 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.526 Å) | | 主引用文献 | Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus.
Proc.Natl.Acad.Sci.USA, 112, 2015
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2YK3
 | | CRITHIDIA FASCICULATA CYTOCHROME C | | 分子名称: | CYTOCHROME C, HEME C, SULFATE ION | | 著者 | Fulop, V, Sam, K.A, Ferguson, S.J, Ginger, M.L, Allen, J.W.A. | | 登録日 | 2011-05-25 | | 公開日 | 2011-06-15 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Structure of a Trypanosomatid Mitochondrial Cytochrome C with Heme Attached Via Only One Thioether Bond and Implications for the Substrate Recognition Requirements of Heme Lyase.
FEBS J., 276, 2009
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2N2Q
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4WFA
 | | The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with linezolid | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 23S rRNA, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | 著者 | Eyal, Z, Matzov, D, Krupkin, M, Wekselman, I, Zimmerman, E, Rozenberg, H, Bashan, A, Yonath, A.E. | | 登録日 | 2014-09-14 | | 公開日 | 2015-10-21 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.392 Å) | | 主引用文献 | Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus.
Proc.Natl.Acad.Sci.USA, 112, 2015
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4WBB
 | | Single Turnover Autophosphorylation Cycle of the PKA RIIb Holoenzyme | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ... | | 著者 | Zhang, P, Knape, M.J, Ahuja, L.G, Keshwani, M.M, King, C.C, Sastri, M, Herberg, F.W, Taylor, S.S. | | 登録日 | 2014-09-02 | | 公開日 | 2015-05-20 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Single Turnover Autophosphorylation Cycle of the PKA RII beta Holoenzyme.
Plos Biol., 13, 2015
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4CE4
 | | 39S large subunit of the porcine mitochondrial ribosome | | 分子名称: | 16S Ribosomal RNA, ICT1, MRPL13, ... | | 著者 | Greber, B.J, Boehringer, D, Leitner, A, Bieri, P, Voigts-Hoffmann, F, Erzberger, J.P, Leibundgut, M, Aebersold, R, Ban, N. | | 登録日 | 2013-11-08 | | 公開日 | 2013-12-18 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | | 主引用文献 | Architecture of the Large Subunit of the Mammalian Mitochondrial Ribosome.
Nature, 505, 2014
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2PHE
 | | Model for VP16 binding to PC4 | | 分子名称: | Alpha trans-inducing protein, TRANSCRIPTIONAL COACTIVATOR PC4 | | 著者 | Jonker, H.R.A, Wechselberger, R.W, Boelens, R, Folkers, G.E, Kaptein, R. | | 登録日 | 2007-04-11 | | 公開日 | 2007-04-24 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Properties of the Promiscuous VP16 Activation Domain
Biochemistry, 44, 2005
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1SUU
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2PHG
 | | Model for VP16 binding to TFIIB | | 分子名称: | Alpha trans-inducing protein, Transcription initiation factor IIB | | 著者 | Jonker, H.R.A, Wechselberger, R.W, Boelens, R, Folkers, G.E, Kaptein, R. | | 登録日 | 2007-04-11 | | 公開日 | 2007-04-24 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Properties of the Promiscuous VP16 Activation Domain
Biochemistry, 44, 2005
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1B6F
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1CIS
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2RB4
 | | Crystal structure of the Helicase domain of human DDX25 RNA helicase | | 分子名称: | ATP-dependent RNA helicase DDX25, CHLORIDE ION, SULFATE ION, ... | | 著者 | Lehtio, L, Hogbom, M, Uppenberg, J, Arrowsmith, C.H, Berglund, H, Edwards, A.M, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hallberg, B.M, Hammarstrom, M, Kotenyova, T, Nilsson-Ehle, P, Nordlund, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Van den Berg, S, Weigelt, J, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC) | | 登録日 | 2007-09-18 | | 公開日 | 2007-10-02 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Comparative Structural Analysis of Human DEAD-Box RNA Helicases.
Plos One, 5, 2010
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1RPQ
 | | High Affinity IgE Receptor (alpha chain) Complexed with Tight-Binding E131 'zeta' Peptide from Phage Display | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Stamos, J, Eigenbrot, C, Nakamura, G.R, Reynolds, M.E, Yin, J.P, Lowman, H.B, Fairbrother, W.J, Starovasnik, M.A. | | 登録日 | 2003-12-03 | | 公開日 | 2004-07-20 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Convergent Recognition of the IgE Binding Site on the High-Affinity IgE Receptor.
Structure, 12, 2004
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7PD9
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7PCP
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