Crystal structure of the Helicase domain of human DDX25 RNA helicase

Replaces:  2G2J

Summary for 2RB4

DescriptorATP-dependent RNA helicase DDX25, CHLORIDE ION, SULFATE ION, ... (5 entities in total)
Functional Keywordsrna helicase, rossmann fold, structural genomics, structural genomics consortium, sgc, alternative initiation, atp-binding, developmental protein, differentiation, hydrolase, mrna transport, nucleotide-binding, nucleus, phosphorylation, rna-binding, spermatogenesis, translation regulation, transport
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm  Q9UHL0
Total number of polymer chains2
Total molecular weight40660.72
Primary citation
Schutz, P.,Karlberg, T.,van den Berg, S.,Collins, R.,Lehtio, L.,Hogbom, M.,Holmberg-Schiavone, L.,Tempel, W.,Park, H.W.,Hammarstrom, M.,Moche, M.,Thorsell, A.G.,Schuler, H.
Comparative Structural Analysis of Human DEAD-Box RNA Helicases.
Plos One, 5:12791-12791, 2010
PubMed: 20941364 (PDB entries with the same primary citation)
DOI: 10.1371/journal.pone.0012791
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.29491.3%4.8%2.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution