7PCP

Crystal structure of CD73 in complex with 5-iodouracil in the open form

Summary for 7PCP

• Entry DOI: 10.2210/pdb7pcp/pdb
• Descriptor: 5'-nucleotidase, ZINC ION, CALCIUM ION, ... (6 entities in total)
• Functional Keywords: ecto-5'-nucleotidase, en, inhibitor, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 60951.35

Authors

Scaletti, E.R.,Strater, N. (deposition date: 2021-08-03, release date: 2021-10-13, Last modification date: 2024-01-31)

• Primary citation: Scaletti, E.,Huschmann, F.U.,Mueller, U.,Weiss, M.S.,Strater, N.; Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5'-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives.; Purinergic Signal, 17:693-704, 2021; PubMed: 34403084; DOI: 10.1007/s11302-021-09802-w

Experimental method

X-RAY DIFFRACTION (1.377 Å)