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7QGN
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BU of 7qgn by Molmil
Structure of the SmrB-bound E. coli disome - stalled 70S ribosome
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Kratzat, H, Buschauer, R, Berninghausen, O, Beckmann, R.
登録日2021-12-09
公開日2022-04-27
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Ribosome collisions induce mRNA cleavage and ribosome rescue in bacteria.
Nature, 603, 2022
8D82
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BU of 8d82 by Molmil
Cryo-EM structure of human IL-6 signaling complex in detergent: model containing full extracellular domains
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-6, ...
著者Zhou, Y, Franklin, M.C.
登録日2022-06-07
公開日2023-03-29
実験手法ELECTRON MICROSCOPY (3.22 Å)
主引用文献Structural insights into the assembly of gp130 family cytokine signaling complexes.
Sci Adv, 9, 2023
8DHA
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BU of 8dha by Molmil
Leptin-bound leptin receptor complex- focused interaction
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Leptin, Leptin receptor
著者Saxton, R.A, Caveney, N.A, Garcia, K.C.
登録日2022-06-25
公開日2023-04-19
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural insights into the mechanism of leptin receptor activation.
Nat Commun, 14, 2023
8DH8
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BU of 8dh8 by Molmil
Leptin-bound leptin receptor complex-full ECD
分子名称: Leptin, Leptin receptor
著者Saxton, R.A, Caveney, N.A, Garcia, K.C.
登録日2022-06-25
公開日2023-04-19
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (5.9 Å)
主引用文献Structural insights into the mechanism of leptin receptor activation.
Nat Commun, 14, 2023
6DMB
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BU of 6dmb by Molmil
Cryo-EM structure of human Ptch1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ...
著者Yan, N, Gong, X, Qian, H.W.
登録日2018-06-04
公開日2018-07-11
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis for the recognition of Sonic Hedgehog by human Patched1.
Science, 361, 2018
5LZD
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BU of 5lzd by Molmil
Structure of SelB-Sec-tRNASec bound to the 70S ribosome in the GTPase activated state (GA)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Fischer, N, Neumann, P, Bock, L.V, Maracci, C, Wang, Z, Paleskava, A, Konevega, A.L, Schroeder, G.F, Grubmueller, H, Ficner, R, Rodnina, M.V, Stark, H.
登録日2016-09-29
公開日2016-11-23
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献The pathway to GTPase activation of elongation factor SelB on the ribosome.
Nature, 540, 2016
2FST
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BU of 2fst by Molmil
mitogen activated protein kinase p38alpha (D176A+F327L) activating mutant
分子名称: Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside
著者Diskin, R, Livnah, O.
登録日2006-01-23
公開日2006-12-05
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structures of p38alpha Active Mutants Reveal Conformational Changes in L16 Loop that Induce Autophosphorylation and Activation
J.Mol.Biol., 365, 2007
2FSM
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BU of 2fsm by Molmil
mitogen activated protein kinase p38alpha (D176A+F327S) activating mutant form-B
分子名称: Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside
著者Diskin, R, Livnah, O.
登録日2006-01-23
公開日2006-12-05
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Structures of p38alpha Active Mutants Reveal Conformational Changes in L16 Loop that Induce Autophosphorylation and Activation
J.Mol.Biol., 365, 2007
5MDV
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BU of 5mdv by Molmil
Structure of ArfA and RF2 bound to the 70S ribosome (accommodated state)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者James, N.R, Brown, A, Gordiyenko, Y, Ramakrishnan, V.
登録日2016-11-13
公開日2016-12-14
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Translational termination without a stop codon.
Science, 354, 2016
2FSO
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BU of 2fso by Molmil
mitogen activated protein kinase p38alpha (D176A) activating mutant
分子名称: Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside
著者Diskin, R, Livnah, O.
登録日2006-01-23
公開日2006-12-05
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Structures of p38alpha Active Mutants Reveal Conformational Changes in L16 Loop that Induce Autophosphorylation and Activation
J.Mol.Biol., 365, 2007
2FSL
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BU of 2fsl by Molmil
mitogen activated protein kinase p38alpha (D176A+F327S) activating mutant form-A
分子名称: Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside
著者Diskin, R, Livnah, O.
登録日2006-01-23
公開日2006-12-05
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structures of p38alpha Active Mutants Reveal Conformational Changes in L16 Loop that Induce Autophosphorylation and Activation
J.Mol.Biol., 365, 2007
5MDY
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BU of 5mdy by Molmil
Structure of ArfA and TtRF2 bound to the 70S ribosome (pre-accommodated state)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者James, N.R, Brown, A, Gordiyenko, Y, Ramakrishnan, V.
登録日2016-11-13
公開日2016-12-21
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Translational termination without a stop codon.
Science, 354, 2016
6DMY
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BU of 6dmy by Molmil
Cryo-EM structure of human Ptch1 and ShhN complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Yan, N, Gong, X, Qian, H.W.
登録日2018-06-05
公開日2018-07-11
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural basis for the recognition of Sonic Hedgehog by human Patched1.
Science, 361, 2018
6DMO
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BU of 6dmo by Molmil
Cryo-EM structure of human Ptch1 with three mutations L282Q/T500F/P504L
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Protein patched homolog 1
著者Yan, N, Gong, X, Qian, H.W.
登録日2018-06-05
公開日2018-07-11
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural basis for the recognition of Sonic Hedgehog by human Patched1.
Science, 361, 2018
5MDZ
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BU of 5mdz by Molmil
Structure of the 70S ribosome (empty A site)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者James, N.R, Brown, A, Gordiyenko, Y, Ramakrishnan, V.
登録日2016-11-13
公開日2016-12-14
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Translational termination without a stop codon.
Science, 354, 2016
4R8H
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BU of 4r8h by Molmil
The role of protein-ligand contacts in allosteric regulation of the Escherichia coli Catabolite Activator Protein
分子名称: 6-(6-AMINO-PURIN-9-YL)-2-THIOXO-TETRAHYDRO-2-FURO[3,2-D][1,3,2]DIOXAPHOSPHININE-2,7-DIOL, GLYCEROL, cAMP-activated global transcriptional regulator CRP
著者Townsend, P.D, Pohl, E, McLeish, T.C.B, Rodgers, T.L, Glover, L.C, Korhonen, H.J, Wilson, M.R, Hodgson, D.R.W, Cann, M.J.
登録日2014-09-02
公開日2015-07-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献The Role of Protein-Ligand Contacts in Allosteric Regulation of the Escherichia coli Catabolite Activator Protein.
J.Biol.Chem., 290, 2015
5LZB
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BU of 5lzb by Molmil
Structure of SelB-Sec-tRNASec bound to the 70S ribosome in the initial binding state (IB)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Fischer, N, Neumann, P, Bock, L.V, Maracci, C, Wang, Z, Paleskava, A, Konevega, A.L, Schroeder, G.F, Grubmueller, H, Ficner, R, Rodnina, M.V, Stark, H.
登録日2016-09-29
公開日2016-11-23
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (5.3 Å)
主引用文献The pathway to GTPase activation of elongation factor SelB on the ribosome.
Nature, 540, 2016
5LZE
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BU of 5lze by Molmil
Structure of the 70S ribosome with Sec-tRNASec in the classical pre-translocation state (C)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Fischer, N, Neumann, P, Bock, L.V, Maracci, C, Wang, Z, Paleskava, A, Konevega, A.L, Schroeder, G.F, Grubmueller, H, Ficner, R, Rodnina, M.V, Stark, H.
登録日2016-09-29
公開日2016-11-23
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献The pathway to GTPase activation of elongation factor SelB on the ribosome.
Nature, 540, 2016
5LZC
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BU of 5lzc by Molmil
Structure of SelB-Sec-tRNASec bound to the 70S ribosome in the codon reading state (CR)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Fischer, N, Neumann, P, Bock, L.V, Maracci, C, Wang, Z, Paleskava, A, Konevega, A.L, Schroeder, G.F, Grubmueller, H, Ficner, R, Rodnina, M.V, Stark, H.
登録日2016-09-29
公開日2016-11-23
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献The pathway to GTPase activation of elongation factor SelB on the ribosome.
Nature, 540, 2016
5MDW
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BU of 5mdw by Molmil
Structure of ArfA(A18T) and RF2 bound to the 70S ribosome (pre-accommodated state)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者James, N.R, Brown, A, Gordiyenko, Y, Ramakrishnan, V.
登録日2016-11-13
公開日2016-12-14
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.06 Å)
主引用文献Translational termination without a stop codon.
Science, 354, 2016
5NWY
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BU of 5nwy by Molmil
2.9 A cryo-EM structure of VemP-stalled ribosome-nascent chain complex
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Su, T, Cheng, J, Sohmen, D, Hedman, R, Berninghausen, O, von Heijne, G, Wilson, D.N, Beckmann, R.
登録日2017-05-08
公開日2017-07-19
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献The force-sensing peptide VemP employs extreme compaction and secondary structure formation to induce ribosomal stalling.
Elife, 6, 2017
5MGP
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BU of 5mgp by Molmil
Structural basis for ArfA-RF2 mediated translation termination on stop-codon lacking mRNAs
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Huter, P, Mueller, C, Beckert, B, Arenz, S, Berninghausen, O, Beckmann, R, Wilson, N.D.
登録日2016-11-21
公開日2016-12-14
最終更新日2017-08-30
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis for ArfA-RF2-mediated translation termination on mRNAs lacking stop codons.
Nature, 541, 2017
5O2R
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BU of 5o2r by Molmil
Cryo-EM structure of the proline-rich antimicrobial peptide Api137 bound to the terminating ribosome
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Graf, M, Berninghausen, O, Beckmann, R, Wilson, D.N.
登録日2017-05-22
公開日2017-07-26
最終更新日2019-02-20
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome.
Nat. Struct. Mol. Biol., 24, 2017
4WZD
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BU of 4wzd by Molmil
Complex of 70S ribosome with cognate tRNA-Tyr in the P-site
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
登録日2014-11-19
公開日2015-06-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
4WSM
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BU of 4wsm by Molmil
Complex of 70S ribosome with tRNA-Leu and mRNA with G-U mismatch in the first position in the A- and P-sites
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
登録日2014-10-28
公開日2015-06-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015

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