5O2R

Cryo-EM structure of the proline-rich antimicrobial peptide Api137 bound to the terminating ribosome

This is a non-PDB format compatible entry.

Summary for 5O2R

• Entry DOI: 10.2210/pdb5o2r/pdb
• EMDB information: 3730
• Descriptor: 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... (58 entities in total)
• Functional Keywords: ribosome, termination, release factors, antimicrobial peptides, antibiotic
• Biological source: Escherichia coli K-12; More
• Total number of polymer chains: 58
• Total formula weight: 2196433.95

Authors

Graf, M.,Berninghausen, O.,Beckmann, R.,Wilson, D.N. (deposition date: 2017-05-22, release date: 2017-07-26, Last modification date: 2019-02-20)

• Primary citation: Florin, T.,Maracci, C.,Graf, M.,Karki, P.,Klepacki, D.,Berninghausen, O.,Beckmann, R.,Vazquez-Laslop, N.,Wilson, D.N.,Rodnina, M.V.,Mankin, A.S.; An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome.; Nat. Struct. Mol. Biol., 24:752-757, 2017; PubMed: 28741611; DOI: 10.1038/nsmb.3439

Experimental method

ELECTRON MICROSCOPY (3.4 Å)