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3LC0
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Histidyl-tRNA synthetase from Trypanosoma cruzi (Histidine complex)
分子名称: HISTIDINE, Histidyl-tRNA synthetase
著者Merritt, E.A, Larson, E.T, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日2010-01-08
公開日2010-01-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structures of Trypanosomal Histidyl-tRNA Synthetase Illuminate Differences between Eukaryotic and Prokaryotic Homologs.
J.Mol.Biol., 397, 2010
6H58
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Structure of a hibernating 100S ribosome reveals an inactive conformation of the ribosomal protein S1 - Full 100S Hibernating E. coli Ribosome
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S1, ...
著者Beckert, B, Turk, M, Czech, A, Berninghausen, O, Beckmann, R, Ignatova, Z, Plitzko, J, Wilson, D.N.
登録日2018-07-24
公開日2018-09-05
最終更新日2018-10-24
実験手法ELECTRON MICROSCOPY (7.9 Å)
主引用文献Structure of a hibernating 100S ribosome reveals an inactive conformation of the ribosomal protein S1.
Nat Microbiol, 3, 2018
5FXI
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GluN1b-GluN2B NMDA receptor structure in non-active-2 conformation
分子名称: N-METHYL-D-ASPARTATE RECEPTOR GLUN1, N-METHYL-D-ASPARTATE RECEPTOR GLUN2B
著者Tajima, N, Karakas, E, Grant, T, Simorowski, N, Diaz-Avalos, R, Grigorieff, N, Furukawa, H.
登録日2016-03-02
公開日2016-05-11
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (6.4 Å)
主引用文献Activation of Nmda Receptors and the Mechanism of Inhibition by Ifenprodil.
Nature, 534, 2016
6GLW
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Structure of galectin-10 in complex with the Fab fragment of a Charcot-Leyden crystal solubilizing antibody, 1D11
分子名称: ACETATE ION, Fab 1D11 - Heavy chain, Fab 1D11 - Light chain, ...
著者Verstraete, K, Verschueren, K, Savvides, S.N.
登録日2018-05-23
公開日2019-06-05
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Protein crystallization promotes type 2 immunity and is reversible by antibody treatment.
Science, 364, 2019
6GN0
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Exoenzyme S from Pseudomonas aeruginosa in complex with human 14-3-3 protein beta, tetrameric crystal form
分子名称: 14-3-3 protein beta/alpha, Exoenzyme S
著者Karlberg, T, Pinto, A.F, Hornyak, P, Nareoja, K, Schuler, H.
登録日2018-05-29
公開日2018-09-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.24 Å)
主引用文献14-3-3 proteins activate Pseudomonas exotoxins-S and -T by chaperoning a hydrophobic surface.
Nat Commun, 9, 2018
6GNN
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Exoenzyme T from Pseudomonas aeruginosa in complex with human 14-3-3 protein beta, tetrameric crystal form bound to STO1101
分子名称: 14-3-3 protein beta/alpha, 3-(12-oxidanylidene-7-thia-9,11-diazatricyclo[6.4.0.0^{2,6}]dodeca-1(8),2(6),9-trien-10-yl)propanoic acid, Exoenzyme T
著者Karlberg, T, Pinto, A.F, Hornyak, P, Thorsell, A.G, Nareoja, K, Schuler, H.
登録日2018-05-31
公開日2018-09-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.79 Å)
主引用文献14-3-3 proteins activate Pseudomonas exotoxins-S and -T by chaperoning a hydrophobic surface.
Nat Commun, 9, 2018
6GKT
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X-ray structure of a non-autocrystallizing galectin-10 variant, Gal10-Tyr69Glu
分子名称: Galectin-10, HEXAETHYLENE GLYCOL, TETRAETHYLENE GLYCOL, ...
著者Verstraete, K, Verschueren, K, Savvides, S.N.
登録日2018-05-21
公開日2019-06-05
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Protein crystallization promotes type 2 immunity and is reversible by antibody treatment.
Science, 364, 2019
6GN8
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Exoenzyme S from Pseudomonas aeruginosa in complex with human 14-3-3 protein beta, trimeric crystal form
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 14-3-3 protein beta/alpha, Exoenzyme S
著者Karlberg, T, Pinto, A.F, Hornyak, P, Thorsell, A.G, Nareoja, K, Schuler, H.
登録日2018-05-30
公開日2018-09-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献14-3-3 proteins activate Pseudomonas exotoxins-S and -T by chaperoning a hydrophobic surface.
Nat Commun, 9, 2018
4A7X
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Crystal structure of uridylate kinase from Helicobacter pylori
分子名称: URIDINE-5'-DIPHOSPHATE, URIDYLATE KINASE
著者Chu, C.H, Liu, M.H, Chen, P.C, Sun, Y.J.
登録日2011-11-15
公開日2012-06-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Structures of Helicobacter Pylori Uridylate Kinase: Insight Into Release of the Product Udp
Acta Crystallogr.,Sect.D, 68, 2012
5E3L
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Crystal structure of Fis bound to 27bp DNA F1-8G (AAATTGGTTTGAATTTTGAGCCAATTT)
分子名称: DNA (27-MER), DNA-binding protein Fis
著者Hancock, S.P, Cascio, D, Johnson, R.C.
登録日2015-10-03
公開日2016-03-23
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献DNA Sequence Determinants Controlling Affinity, Stability and Shape of DNA Complexes Bound by the Nucleoid Protein Fis.
Plos One, 11, 2016
5FRP
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BU of 5frp by Molmil
Structure of the Pds5-Scc1 complex and implications for cohesin function
分子名称: MCD1-LIKE PROTEIN, SISTER CHROMATID COHESION PROTEIN PDS5
著者Muir, K.W, Kschonsak, M, Li, Y, Metz, J, Haering, C.H, Panne, D.
登録日2015-12-21
公開日2016-03-02
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.895 Å)
主引用文献Structure of the Pds5-Scc1 Complex and Implications for Cohesin Function
Cell Rep., 14, 2016
5FFT
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Crystal Structure of Surfactant Protein-A Y221A Mutant
分子名称: CALCIUM ION, Pulmonary surfactant-associated protein A
著者Goh, B.C, Wu, H, Rynkiewicz, M.J, Schulten, K, Seaton, B.A, McCormack, F.X.
登録日2015-12-18
公開日2016-07-06
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Elucidation of Lipid Binding Sites on Lung Surfactant Protein A Using X-ray Crystallography, Mutagenesis, and Molecular Dynamics Simulations.
Biochemistry, 55, 2016
3LN2
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Crystal Structure of a Charge Engineered Human Lysozyme Variant
分子名称: Lysozyme C
著者Gill, A, Scanlon, T.C, Griswold, K.E.
登録日2010-02-01
公開日2011-02-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.037 Å)
主引用文献Crystal structure of a charge engineered human lysozyme having enhanced bactericidal activity.
Plos One, 6, 2011
5WQQ
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High resolution structure of high-potential iron-sulfur protein in the oxidized state
分子名称: GLYCEROL, High-potential iron-sulfur protein, IRON/SULFUR CLUSTER, ...
著者Ohno, H, Takeda, K, Niwa, S, Tsujinaka, T, Hanazono, Y, Hirano, Y, Miki, K.
登録日2016-11-28
公開日2017-06-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (0.8 Å)
主引用文献Crystallographic characterization of the high-potential iron-sulfur protein in the oxidized state at 0.8 angstrom resolution
PLoS ONE, 12, 2017
3MJL
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Crystal structure of human arginase I in complex with 2-aminoimidazole. Resolution 1.90 A.
分子名称: 1H-imidazol-2-amine, Arginase-1, MANGANESE (II) ION
著者Di Costanzo, L, Christianson, D.W.
登録日2010-04-13
公開日2010-05-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of human arginase I in complex with 2-aminoimidazole. Resolution 1.90 A.
To be Published
3T46
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Crystal structure of Staphylococcal Complement Inhibitor D (SCIN-D) at 1.5 Angstrom
分子名称: SCIN-D, SODIUM ION
著者Garcia, B.L, Geisbrecht, B.V, Summers, B.J.
登録日2011-07-25
公開日2011-11-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Diversity in the C3b Convertase Contact Residues and Tertiary Structures of the Staphylococcal Complement Inhibitor (SCIN) Protein Family.
J.Biol.Chem., 287, 2012
4A6R
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Crystal structure of the omega transaminase from Chromobacterium violaceum in the apo form, crystallised from polyacrylic acid
分子名称: OMEGA TRANSAMINASE, POLYACRYLIC ACID
著者Logan, D.T, Hakansson, M, Yengo, K, Svedendahl Humble, M, Engelmark Cassimjee, K, Walse, B, Abedi, V, Federsel, H.-J, Berglund, P.
登録日2011-11-08
公開日2012-01-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.349 Å)
主引用文献Crystal Structures of the Chromobacterium Violaceum Omega-Transaminase Reveal Major Structural Rearrangements Upon Binding of Coenzyme Plp.
FEBS J., 279, 2012
3MI9
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Crystal structure of HIV-1 Tat complexed with human P-TEFb
分子名称: Cell division protein kinase 9, Cyclin-T1, Protein Tat, ...
著者Tahirov, T.H, Babayeva, N.D, Varzavand, K, Cooper, J.J, Sedore, S.C, Price, D.H.
登録日2010-04-09
公開日2010-06-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of HIV-1 Tat complexed with human P-TEFb.
Nature, 465, 2010
3T49
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Crystal structure of truncated form of Staphylococcal Complement Inhibitor B (SCIN-B) at 1.5 Angstrom
分子名称: Fibrinogen-binding protein, GLYCEROL, SULFATE ION
著者Garcia, B.L, Geisbrecht, B.V, Summers, B.J.
登録日2011-07-25
公開日2011-11-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Diversity in the C3b Convertase Contact Residues and Tertiary Structures of the Staphylococcal Complement Inhibitor (SCIN) Protein Family.
J.Biol.Chem., 287, 2012
3O5N
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Tetrahydroquinoline carboxylates are potent inhibitors of the Shank PDZ domain, a putative target in autism disorders
分子名称: (3aS,4R,9bR)-9-nitro-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4,6-dicarboxylic acid, SH3 and multiple ankyrin repeat domains protein 3
著者Saupe, J, Roske, Y, Schillinger, C, Kamdem, N, Radetzki, S, Diehl, A, Oschkinat, H, Krause, G, Heinemann, U, Rademann, J.
登録日2010-07-28
公開日2011-06-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Discovery, structure-activity relationship studies, and crystal structure of nonpeptide inhibitors bound to the shank3 PDZ domain.
Chemmedchem, 6, 2011
4B73
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Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function
分子名称: (2S)-4-amino-N-[(1R)-1-(4-chloro-2-fluoro-3-phenoxyphenyl)propyl]-4-oxobutan-2-aminium, NON-STRUCTURAL PROTEIN 4A, SERINE PROTEASE NS3
著者Saalau-Bethell, S.M, Woodhead, A.J, Chessari, G, Carr, M.G, Coyle, J, Graham, B, Hiscock, S.D, Murray, C.W, Pathuri, P, Rich, S.J, Richardson, C.J, Williams, P.A, Jhoti, H.
登録日2012-08-16
公開日2012-10-03
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Discovery of an Allosteric Mechanism for the Regulation of Hcv Ns3 Protein Function.
Nat.Chem.Biol., 8, 2012
3SOH
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Architecture of the Flagellar Rotor
分子名称: Flagellar motor switch protein FliG, Flagellar motor switch protein FliM
著者Koushik, P, Gonzalez-Bonet, G, Bilwes, A.M, Crane, B.R, Blair, D.
登録日2011-06-30
公開日2011-07-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Architecture of the flagellar rotor.
Embo J., 30, 2011
3I5L
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Allosteric Modulation of DNA by Small Molecules
分子名称: (22R,51R)-22,51-diamino-5,11,17,28,34,40,46,57-octamethyl-2,5,8,11,14,17,20,25,28,31,34,37,40,43,46,49,54,57,60,61,64,6 5-docosaazanonacyclo[54.2.1.1~4,7~.1~10,13~.1~16,19~.1~27,30~.1~33,36~.1~39,42~.1~45,48~]hexahexaconta-1(58),4(66),6,10( 65),12,16(64),18,27(63),29,33(62),35,39(61),41,45(60),47,56(59)-hexadecaene-3,9,15,21,26,32,38,44,50,55-decone, 5'-D(*CP*CP*AP*GP*GP*(C38)P*CP*TP*GP*G)-3', CALCIUM ION
著者Chenoweth, D.M, Dervan, P.B.
登録日2009-07-05
公開日2009-07-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.18 Å)
主引用文献Allosteric modulation of DNA by small molecules
Proc.Natl.Acad.Sci.USA, 106, 2009
5HFM
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Gp41-targeting HIV-1 fusion inhibitors with hook-like Ile-Asp-Leu tail
分子名称: Envelope glycoprotein gp160,gp41 CHR region, TRIS(HYDROXYETHYL)AMINOMETHANE
著者Zhu, Y, Ye, S, Zhang, R.
登録日2016-01-07
公開日2017-01-11
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.298 Å)
主引用文献Rational improvement of gp41-targeting HIV-1 fusion inhibitors: an innovatively designed Ile-Asp-Leu tail with alternative conformations
Sci Rep, 6, 2016
6G6J
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The crystal structures of Human MYC:MAX bHLHZip complex
分子名称: Myc proto-oncogene protein, Protein max, SULFATE ION
著者Allen, M.D, Zinzalla, G.
登録日2018-04-01
公開日2019-04-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal Structures and Nuclear Magnetic Resonance Studies of the Apo Form of the c-MYC:MAX bHLHZip Complex Reveal a Helical Basic Region in the Absence of DNA.
Biochemistry, 58, 2019

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