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4YVD
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Crytsal structure of human Pleiotropic Regulator 1 (PRL1)
分子名称: CHLORIDE ION, Pleiotropic regulator 1, SODIUM ION, ...
著者Dong, A, Zeng, H, Xu, C, Tempel, W, Li, Y, He, H, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Min, J, Wu, H, Structural Genomics Consortium (SGC)
登録日2015-03-19
公開日2015-04-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crytsal structure of human Pleiotropic Regulator 1 (PRL1).
to be published
1MQ7
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CRYSTAL STRUCTURE OF DUTPASE FROM MYCOBACTERIUM TUBERCULOSIS (RV2697C)
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE
著者Sawaya, M.R, Chan, S, Segelke, B.W, Lekin, T, Heike, K, Cho, U.S, Naranjo, C, Perry, L.J, Yeates, T.O, Eisenberg, D, TB Structural Genomics Consortium (TBSGC)
登録日2002-09-13
公開日2002-10-09
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of the Mycobacterium tuberculosis dUTPase: insights into the catalytic mechanism.
J.Mol.Biol., 341, 2004
7ZBF
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Crystal structure of native Iripin-4 serpin from tick Ixodes ricinus
分子名称: Iripin-4 serpin, NICKEL (II) ION
著者Kascakova, B, Kuta Smatanova, I, Chmelar, J, Prudnikova, T.
登録日2022-03-23
公開日2023-04-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Conformational transition of the Ixodes ricinus salivary serpin Iripin-4.
Acta Crystallogr D Struct Biol, 79, 2023
1M03
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Mutant Streptomyces plicatus beta-hexosaminidase (D313A) in complex with product (GlcNAc)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-N-acetylhexosaminidase, CHLORIDE ION, ...
著者Williams, S.J, Mark, B.L, Vocadlo, D.J, James, M.N.G, Withers, S.G.
登録日2002-06-11
公開日2002-12-11
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Aspartate 313 in the Streptomyces plicatus hexosaminidase plays a critical role in substrate-assisted catalysis by orienting the 2-acetamido group and stabilizing the transition state.
J.Biol.Chem., 277, 2002
4YM2
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Crystal structure of the human galectin-4 C-terminal carbohydrate recognition domain in complex with lactose-3'-sulfate
分子名称: 3-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, Galectin-4, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
著者Bum-Erdene, K, Blanchard, H.
登録日2015-03-06
公開日2015-07-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural characterization of human galectin-4 C-terminal domain: elucidating the molecular basis for recognition of glycosphingolipids, sulfated saccharides and blood group antigens.
Febs J., 282, 2015
4YVP
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Crystal Structure of AKR1C1 complexed with glibenclamide
分子名称: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, Aldo-keto reductase family 1 member C1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Zhao, Y, Zheng, X, Zhang, H, Hu, X.
登録日2015-03-20
公開日2015-11-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献In vitro inhibition of AKR1Cs by sulphonylureas and the structural basis
Chem.Biol.Interact., 240, 2015
1MQH
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Crystal Structure of the GluR2 Ligand Binding Core (S1S2J) in Complex with Bromo-Willardiine at 1.8 Angstroms Resolution
分子名称: 2-AMINO-3-(5-BROMO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, glutamate receptor 2
著者Jin, R, Banke, T.G, Mayer, M.L, Traynelis, S.F, Gouaux, E.
登録日2002-09-16
公開日2003-08-05
最終更新日2017-08-02
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for partial agonist action at ionotropic glutamate receptors
Nat.Neurosci., 6, 2003
4YMD
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CL-K1 trimer bound to man(alpha1-2)man
分子名称: CALCIUM ION, Collectin-11, GLYCEROL, ...
著者Wallis, R, Venkatraman Girija, U, Gingras, A.R, Moody, P.C.E, Marshall, J.E.
登録日2015-03-06
公開日2015-04-08
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.87 Å)
主引用文献Molecular basis of sugar recognition by collectin-K1 and the effects of mutations associated with 3MC syndrome.
Bmc Biol., 13, 2015
1M0M
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BACTERIORHODOPSIN M1 INTERMEDIATE AT 1.43 A RESOLUTION
分子名称: 1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL, 2,10,23-TRIMETHYL-TETRACOSANE, BACTERIORHODOPSIN, ...
著者Lanyi, J.K.
登録日2002-06-13
公開日2002-09-11
最終更新日2015-09-09
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Crystallographic structure of the retinal and the protein after deprotonation of the Schiff base: the switch in the bacteriorhodopsin photocycle.
J.Mol.Biol., 321, 2002
4YMW
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Crystal structure of an amino acid ABC transporter with histidines
分子名称: ABC-type amino acid transport system, permease component, ABC-type polar amino acid transport system, ...
著者Ge, J, Yu, J, Yang, M.
登録日2015-03-07
公開日2015-04-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.804 Å)
主引用文献Structural basis for substrate specificity of an amino acid ABC transporter
Proc.Natl.Acad.Sci.USA, 112, 2015
1M4R
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CRYSTAL STRUCTURE OF RECOMBINANT HUMAN INTERLEUKIN-22
分子名称: Interleukin-22
著者Nagem, R.A.P, Colau, D, Dumoutier, L, Renauld, J.-C, Ogata, C, Polikarpov, I.
登録日2002-07-03
公開日2003-07-07
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of Recombinant Human Interleukin-22
Structure, 10, 2002
4YN9
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YfiR mutant-C110S
分子名称: SULFATE ION, YfiR
著者Xu, M, Jiang, T.
登録日2015-03-09
公開日2015-04-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal structures of YfiR from Pseudomonas aeruginosa in two redox states
Biochem.Biophys.Res.Commun., 461, 2015
1M16
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Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag and Leu 44 Replaced with Phe (L44F), Leu 73 Replaced with Val (L73V), Val 109 Replaced with Leu (V109L) and Cys 117 Replaced with Val (C117V).
分子名称: FORMIC ACID, SULFATE ION, acidic fibroblast growth factor
著者Brych, S.R, Kim, J, Spielmann, G.L, Logan, T.M, Blaber, M.
登録日2002-06-17
公開日2003-08-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Accommodation of a highly symmetric core within a symmetric protein superfold
Protein Sci., 12, 2003
4YW3
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Crystal Structure of Streptococcus pneumoniae NanC, complex with Neu5Ac and Neu5Ac2en following soaking with Neu5Ac2en
分子名称: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, GLYCEROL, N-acetyl-alpha-neuraminic acid, ...
著者Owen, C.D, Lukacik, P, Potter, J.A, Walsh, M, Taylor, G.L.
登録日2015-03-20
公開日2015-09-23
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Streptococcus pneumoniae NanC: STRUCTURAL INSIGHTS INTO THE SPECIFICITY AND MECHANISM OF A SIALIDASE THAT PRODUCES A SIALIDASE INHIBITOR.
J.Biol.Chem., 290, 2015
1M1H
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Crystal structure of Aquifex aeolicus N-utilization substance G (NusG), Space group I222
分子名称: Transcription antitermination protein nusG
著者Steiner, T, Kaiser, J.T, Marinkovic, S, Huber, R, Wahl, M.C.
登録日2002-06-19
公開日2003-02-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structures of transcription factor NusG in light of its nucleic acid- and protein-binding activities
Embo J., 21, 2002
4YNO
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Crystal structure of MAPK13 at INACTIVE FORM
分子名称: Mitogen-activated protein kinase 13
著者Miller, C.A, Brett, T.J.
登録日2015-03-10
公開日2015-04-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献IL-13-induced airway mucus production is attenuated by MAPK13 inhibition.
J.Clin.Invest., 122, 2012
1M52
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Crystal Structure of the c-Abl Kinase domain in complex with PD173955
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-(2,6-DICHLORO-PHENYL)-8-METHYL-2-(3-METHYLSULFANYL-PHENYLAMINO)-8H-PYRIDO[2,3-D]PYRIMIDIN-7-ONE, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1
著者Nagar, B, Bornmann, W, Pellicena, P, Schindler, T, Veach, D, Miller, W.T, Clarkson, B, Kuriyan, J.
登録日2002-07-08
公開日2002-09-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structures of the Kinase Domain of c-Abl in Complex with the Small Molecule Inhibitors PD173955 and Imatinib (STI-571)
Cancer Res., 62, 2002
4YWN
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Crystal structure of NADH-FMN oxidoreductase from Mycobacterium avium
分子名称: CITRATE ANION, NADH-fmn oxidoreductase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2015-03-20
公開日2015-04-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of NADH-FMN oxidoreductase from Mycobacterium avium
To be Published
1M1P
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P21 crystal structure of the tetraheme cytochrome c3 from Shewanella oneidensis MR1
分子名称: HEME C, SULFATE ION, Small tetraheme cytochrome c
著者Leys, D, Meyer, T.E, Tsapin, A.I, Nealson, K.H, Cusanovich, M.A, Van Beeumen, J.J.
登録日2002-06-20
公開日2002-08-14
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal structures at atomic resolution reveal the novel concept of 'electron-harvesting' as a role for the small tetraheme cytochrome c
J.Biol.Chem., 277, 2002
4YNY
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Crystal structure of monoclonal anti-human podoplanin antibody NZ-1
分子名称: Heavy chain of antigen binding fragment, Fab, Light chain of antigen binding fragment
著者Fujii, Y, Kitago, Y, Arimori, T, Takagi, J.
登録日2015-03-11
公開日2016-03-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.584 Å)
主引用文献Tailored placement of a turn-forming PA tag into the structured domain of a protein to probe its conformational state
J.Cell.Sci., 129, 2016
1M5A
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Crystal Structure of 2-Co(2+)-Insulin at 1.2A Resolution
分子名称: COBALT (II) ION, INSULIN A CHAIN, INSULIN B CHAIN
著者Nicholson, J.M, Perkins, L.C, Korber, F.C.
登録日2002-07-09
公開日2002-08-14
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献The high-resolution structure of hexameric T6 cobalt insulin: A possible pathway for the T to R transition.
Recent Research Developments in Molecular Biology, 3, 2006
4YWR
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Structure of a putative phosphomethylpyrimidine kinase from Acinetobacter baumannii in non-covalent complex with pyridoxal phosphate
分子名称: PYRIDOXAL-5'-PHOSPHATE, Putative hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2015-03-20
公開日2016-03-02
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Characterization of an Acinetobacter baumannii Monofunctional Phosphomethylpyrimidine Kinase That Is Inhibited by Pyridoxal Phosphate.
Biochemistry, 2024
1M27
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Crystal structure of SAP/FynSH3/SLAM ternary complex
分子名称: CITRATE ANION, Proto-oncogene tyrosine-protein kinase FYN, SH2 domain protein 1A, ...
著者Chan, B, Griesbach, J, Song, H.K, Poy, F, Terhorst, C, Eck, M.J.
登録日2002-06-21
公開日2003-05-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献SAP couples Fyn to SLAM immune receptors.
NAT.CELL BIOL., 5, 2003
4YOI
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Structure of HKU4 3CLpro bound to non-covalent inhibitor 1A
分子名称: 3C-like proteinase, ACETATE ION, FORMIC ACID, ...
著者St John, S.E, Mesecar, A.
登録日2015-03-11
公開日2015-08-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Targeting zoonotic viruses: Structure-based inhibition of the 3C-like protease from bat coronavirus HKU4-The likely reservoir host to the human coronavirus that causes Middle East Respiratory Syndrome (MERS).
Bioorg.Med.Chem., 23, 2015
1M5H
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Formylmethanofuran:tetrahydromethanopterin formyltransferase from Archaeoglobus fulgidus
分子名称: Formylmethanofuran--tetrahydromethanopterin formyltransferase, POTASSIUM ION
著者Mamat, B, Roth, A, Grimm, C, Ermler, U, Tziatzios, C, Schubert, D, Thauer, R.K, Shima, S.
登録日2002-07-09
公開日2002-07-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures and enzymatic properties of three formyltransferases from archaea: environmental adaptation and evolutionary relationship.
Protein Sci., 11, 2002

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