Crystal structure of MAPK13 at INACTIVE FORM

Replaces:  4EXU

Summary for 4YNO

Related4myg 4eyj 4eym
DescriptorMitogen-activated protein kinase 13 (2 entities in total)
Functional Keywordsp38 kinase, transferase
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total molecular weight42633.9
Miller, C.A.,Brett, T.J. (deposition date: 2015-03-10, release date: 2015-04-08, Last modification date: 2019-12-04)
Primary citation
Alevy, Y.G.,Patel, A.C.,Romero, A.G.,Patel, D.A.,Tucker, J.,Roswit, W.T.,Miller, C.A.,Heier, R.F.,Byers, D.E.,Brett, T.J.,Holtzman, M.J.
IL-13-induced airway mucus production is attenuated by MAPK13 inhibition.
J.Clin.Invest., 122:4555-4568, 2012
PubMed: 23187130 (PDB entries with the same primary citation)
DOI: 10.1172/JCI64896
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2254 0.3% 0.3% 9.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-21