1MQH

Crystal Structure of the GluR2 Ligand Binding Core (S1S2J) in Complex with Bromo-Willardiine at 1.8 Angstroms Resolution

Summary for 1MQH

Entry DOI	10.2210/pdb1mqh/pdb
Related	1FTJ 1FTM 1MM6 1MM7 1MQG 1MQI 1MQJ
Descriptor	glutamate receptor 2, 2-AMINO-3-(5-BROMO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID (3 entities in total)
Functional Keywords	ionotropic glutamate receptor, glur2, ligand binding core, s1s2, partial agonist, willardiines, bromo-willardiine, membrane protein
Biological source	Rattus norvegicus (Norway rat) More
Cellular location	Cell membrane; Multi-pass membrane protein: P19491
Total number of polymer chains	1
Total formula weight	29439.62
Authors	Jin, R.,Banke, T.G.,Mayer, M.L.,Traynelis, S.F.,Gouaux, E. (deposition date: 2002-09-16, release date: 2003-08-05, Last modification date: 2017-08-02)
Primary citation	Jin, R.,Banke, T.G.,Mayer, M.L.,Traynelis, S.F.,Gouaux, E. Structural basis for partial agonist action at ionotropic glutamate receptors Nat.Neurosci., 6:803-810, 2003 Cited by PubMed: 12872125 DOI: 10.1038/nn1091 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation