1MM6

crystal structure of the GluR2 ligand binding core (S1S2J) in complex with quisqualate in a non zinc crystal form at 2.15 angstroms resolution

Summary for 1MM6

• Entry DOI: 10.2210/pdb1mm6/pdb
• Related: 1FTJ 1FTM 1MQG 1MQH 1MQI 1MQJ 1mm7
• Descriptor: GLUTAMATE RECEPTOR 2, SULFATE ION, (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, ... (5 entities in total)
• Functional Keywords: ionotropic glutamate receptor, glur2, ligand binding core, s1s2, full agonist, quisqualate, complex, membrane protein
• Biological source: Rattus norvegicus (Norway rat); More
• Cellular location: Cell membrane; Multi-pass membrane protein: P19491
• Total number of polymer chains: 2
• Total formula weight: 59293.99

Authors

Jin, R.,Horning, M.,Mayer, M.L.,Gouaux, E. (deposition date: 2002-09-03, release date: 2003-02-04, Last modification date: 2017-08-23)

• Primary citation: Jin, R.,Horning, M.,Mayer, M.L.,Gouaux, E.; Mechanism of activation and selectivity in a ligand-gated ion channel: Structural and functional studies of GluR2 and quisqualate; Biochemistry, 41:15635-15643, 2002; PubMed: 12501192; DOI: 10.1021/bi020583k

Experimental method

X-RAY DIFFRACTION (2.15 Å)