1M27

Crystal structure of SAP/FynSH3/SLAM ternary complex

Summary for 1M27

• Entry DOI: 10.2210/pdb1m27/pdb
• Related: 1D4T
• Descriptor: SH2 domain protein 1A, Signaling lymphocytic activation molecule, Proto-oncogene tyrosine-protein kinase FYN, ... (5 entities in total)
• Functional Keywords: sh2-sh3 interaction, signaling protein, transferase
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm (Probable): O60880; Cell membrane: P06241; Cell membrane; Single-pass type I membrane protein: Q13291
• Total number of polymer chains: 3
• Total formula weight: 20110.52

Authors

Chan, B.,Griesbach, J.,Song, H.K.,Poy, F.,Terhorst, C.,Eck, M.J. (deposition date: 2002-06-21, release date: 2003-05-06, Last modification date: 2024-02-14)

• Primary citation: Chan, B.,Lanyi, A.,Song, H.K.,Griesbach, J.,Simarro-Grande, M.,Poy, F.,Howie, D.,Sumegi, J.,Terhorst, C.,Eck, M.J.; SAP couples Fyn to SLAM immune receptors.; NAT.CELL BIOL., 5:155-160, 2003; PubMed: 12545174; DOI: 10.1038/ncb920

Experimental method

X-RAY DIFFRACTION (2.5 Å)