PDB: 98225 件ウェブページステータス検索Chemie searchBIRD

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1M7E	Crystal structure of the phosphotyrosine binding domain(PTB) of mouse Disabled 2(Dab2):implications for Reeling signaling 分子名称: Disabled homolog 2, NGYENPTYK peptide 著者 Yun, M, Keshvara, L, Park, C.-G, Zhang, Y.-M, Dickerson, J.B, Zheng, J, Rock, C.O, Curran, T, Park, H.-W. 登録日 2002-07-19 公開日 2003-08-05 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Crystal structures of the Dab homology domains of mouse disabled 1 and 2 J.Biol.Chem., 278, 2003
7A29	Cryo-EM structure of the SARS-CoV-2 spike protein bound to neutralizing sybodies (Sb23) 2-up conformation 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Neutralising sybody (Sb23), ... 著者 Hallberg, B.M, Das, H. 登録日 2020-08-16 公開日 2020-10-21 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (2.94 Å) 主引用文献 Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2. Nat Commun, 11, 2020
7A5M	ENAH EVH1 in complex with Ac-[2-Cl-F]-[ProM-2]-[ProM-17]-OMe 分子名称: Ac-[2-Cl-F]-[ProM-2]-[ProM-17]-OMe, NITRATE ION, Protein enabled homolog 著者 Barone, M, Roske, Y. 登録日 2020-08-21 公開日 2020-10-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (0.78 Å) 主引用文献 Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells. Proc.Natl.Acad.Sci.USA, 117, 2020
1UT4	Structure of the conserved domain of ANAC, a member of the NAC family of transcription factors 分子名称: NO APICAL MERISTEM PROTEIN 著者 Ernst, H.A, Olsen, A.N, Skriver, K, Larsen, S, Lo Leggio, L. 登録日 2003-12-03 公開日 2004-03-19 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of the Conserved Domain of Anac, a Member of the Nac Family of Transcription Factors Embo Rep., 5, 2004
4ZC4	Crystal structure of LARP1-unique domain DM15 分子名称: La-related protein 1, SULFATE ION 著者 Lahr, R.M, Berman, A.J. 登録日 2015-04-15 公開日 2015-08-05 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 The La-related protein 1-specific domain repurposes HEAT-like repeats to directly bind a 5'TOP sequence. Nucleic Acids Res., 43, 2015
3KRR	Crystal Structure of JAK2 complexed with a potent quinoxaline ATP site inhibitor 分子名称: 8-[3,5-difluoro-4-(morpholin-4-ylmethyl)phenyl]-2-(1-piperidin-4-yl-1H-pyrazol-4-yl)quinoxaline, Tyrosine-protein kinase JAK2 著者 Tavares, G.A, Gerspacher, M, Kroemer, M, Scheufler, C. 登録日 2009-11-19 公開日 2010-07-21 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Potent and Selective Inhibition of Polycythemia by the Quinoxaline JAK2 Inhibitor NVP-BSK805 Mol.Cancer Ther., 9, 2010
6DIC	D276G DNA polymerase beta substrate complex with templating cytosine and incoming Fapy-dGTP analog 分子名称: 1-[2-amino-5-(formylamino)-6-oxo-1,6-dihydropyrimidin-4-yl]-2,5-anhydro-1,3-dideoxy-6-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-D-ribo-hexitol, CALCIUM ION, CHLORIDE ION, ... 著者 Freudenthal, B.D, Smith, M.R, Wilson, S.H, Beard, W.A. 登録日 2018-05-23 公開日 2019-01-30 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.992 Å) 主引用文献 A guardian residue hinders insertion of a Fapy•dGTP analog by modulating the open-closed DNA polymerase transition. Nucleic Acids Res., 47, 2019
1QZB	Coordinates of the A-site tRNA model fitted into the cryo-EM map of 70S ribosome in the pre-translocational state 分子名称: Phe-tRNA 著者 Valle, M, Zavialov, A, Li, W, Stagg, S.M, Sengupta, J, Nielsen, R.C, Nissen, P, Harvey, S.C, Ehrenberg, M, Frank, J. 登録日 2003-09-16 公開日 2003-11-04 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (9 Å) 主引用文献 Incorporation of Aminoacyl-tRNA into the Ribosome as seen by Cryo-electron Microscopy Nat.Struct.Biol., 10, 2003
5Y7L	Solution structure of Hbeta4 extracellular loop of BK potassium channel 分子名称: Calcium-activated potassium channel subunit beta-4 著者 Wang, Y, Lan, W, Ding, J, Cao, C. 登録日 2017-08-17 公開日 2018-08-01 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Solution structure of extracellular loop of human beta 4 subunit of BK channel and its biological implication on ChTX sensitivity. Sci Rep, 8, 2018
2H64	Crystal structure of a ternary ligand-receptor complex of BMP-2 分子名称: Acvr2b protein, Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA 著者 Mueller, T.D, Sebald, W, Weber, D. 登録日 2006-05-30 公開日 2007-04-10 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor. Bmc Struct.Biol., 7, 2007
4WW7	Crystal structure of binary complex Bud32-Cgi121 in complex with AMP 分子名称: ACETATE ION, ADENOSINE MONOPHOSPHATE, EKC/KEOPS complex subunit BUD32, ... 著者 Zhang, W, van Tilbeurgh, H. 登録日 2014-11-10 公開日 2015-03-18 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.669 Å) 主引用文献 Crystal structures of the Gon7/Pcc1 and Bud32/Cgi121 complexes provide a model for the complete yeast KEOPS complex. Nucleic Acids Res., 43, 2015
5W41	Zika MR766 NLS in complex with Importin alpha subunit-1 分子名称: Importin subunit alpha-1, ZIKA MR766 NLS 著者 Jeffress, S, Smith, K.M, Forwood, J.K. 登録日 2017-06-08 公開日 2018-06-13 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Zika virus NS5 forms supramolecular nuclear bodies that sequester importin alpha and modulate the host immune and pro-inflammatory response in neuronal cells. ACS Infect Dis, 2019
1V4I	Crystal Structure of Octaprenyl Pyrophosphate Synthase from Hyperthermophilic Thermotoga maritima F132A mutant 分子名称: SULFATE ION, octoprenyl-diphosphate synthase 著者 Guo, R.T, Kuo, C.J, Chou, C.C, Ko, T.P, Shr, H.L, Liang, P.H, Wang, A.H.-J. 登録日 2003-11-14 公開日 2004-03-02 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure of Octaprenyl Pyrophosphate Synthase from Hyperthermophilic Thermotoga maritima and Mechanism of Product Chain Length Determination J.Biol.Chem., 279, 2004
1UXY	MURB MUTANT WITH SER 229 REPLACED BY ALA, COMPLEX WITH ENOLPYRUVYL-UDP-N-ACETYLGLUCOSAMINE 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, URIDINE DIPHOSPHO-N-ACETYLENOLPYRUVYLGLUCOSAMINE REDUCTASE, URIDINE-DIPHOSPHATE-2(N-ACETYLGLUCOSAMINYL) BUTYRIC ACID 著者 Benson, T.E, Walsh, C.T, Hogle, J.M. 登録日 1996-11-08 公開日 1997-04-01 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 X-ray crystal structures of the S229A mutant and wild-type MurB in the presence of the substrate enolpyruvyl-UDP-N-acetylglucosamine at 1.8-A resolution. Biochemistry, 36, 1997
1L83	A CAVITY-CONTAINING MUTANT OF T4 LYSOZYME IS STABILIZED BY BURIED BENZENE 分子名称: BENZENE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... 著者 Eriksson, A.E, Matthews, B.W. 登録日 1992-01-21 公開日 1993-10-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 A cavity-containing mutant of T4 lysozyme is stabilized by buried benzene. Nature, 355, 1992
1VCA	CRYSTAL STRUCTURE OF AN INTEGRIN-BINDING FRAGMENT OF VASCULAR CELL ADHESION MOLECULE-1 AT 1.8 ANGSTROMS RESOLUTION 分子名称: HUMAN VASCULAR CELL ADHESION MOLECULE-1 著者 Jones, E.Y, Harlos, K, Bottomley, M.J, Robinson, R.C, Driscoll, P.C, Edwards, R.M, Clements, J.M, Dudgeon, T.J, Stuart, D.I. 登録日 1995-03-21 公開日 1995-09-15 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of an integrin-binding fragment of vascular cell adhesion molecule-1 at 1.8 A resolution. Nature, 373, 1995
1UMP	GEOMETRY OF TRITERPENE CONVERSION TO PENTACARBOCYCLIC HOPENE 分子名称: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, 2-AZASQUALENE, SQUALENE--HOPENE CYCLASE 著者 Reinert, D.J, Balliano, G, Schulz, G.E. 登録日 2003-08-27 公開日 2004-02-03 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Conversion of Squalene to the Pentacarbocyclic Hopene Chem.Biol., 11, 2004
7AGO	crystal structure of the N-acetylmuramyl-L-alanine amidase, Ami1, from Mycobacterium abscessus bound to L-Alanine-D-isoglutamine 分子名称: ALANINE, D-alpha-glutamine, N-acetylmuramoyl-L-alanine amidase, ... 著者 Blaise, M. 登録日 2020-09-23 公開日 2020-11-18 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Functional Characterization of the N -Acetylmuramyl-l-Alanine Amidase, Ami1, from Mycobacterium abscessus . Cells, 9, 2020
1UMS	STROMELYSIN-1 CATALYTIC DOMAIN WITH HYDROPHOBIC INHIBITOR BOUND, PH 7.0, 32OC, 20 MM CACL2, 15% ACETONITRILE; NMR ENSEMBLE OF 20 STRUCTURES 分子名称: CALCIUM ION, N-{(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoyl}-L-leucyl-L-phenylalaninamide, STROMELYSIN-1, ... 著者 Van Doren, S.R, Kurochkin, A.V, Hu, W, Zuiderweg, E.R.P. 登録日 1995-10-31 公開日 1996-03-08 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution structure of the catalytic domain of human stromelysin complexed with a hydrophobic inhibitor. Protein Sci., 4, 1995
2PFK	THE CRYSTAL STRUCTURE OF UNLIGANDED PHOSPHOFRUCTOKINASE FROM ESCHERICHIA COLI 分子名称: 6-PHOSPHOFRUCTOKINASE ISOZYME I 著者 Rypniewski, W.R, Evans, P.R. 登録日 1988-01-25 公開日 1989-01-09 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of unliganded phosphofructokinase from Escherichia coli. J.Mol.Biol., 207, 1989
7AGM	Crystal structure of the N-acetylmuramyl-L-alanine amidase, Ami1, from Mycobacterium smegmatis 分子名称: N-acetylmuramoyl-L-alanine amidase, ZINC ION 著者 Blaise, M, Alsarraf, M.A.B. 登録日 2020-09-23 公開日 2020-11-18 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Functional Characterization of the N -Acetylmuramyl-l-Alanine Amidase, Ami1, from Mycobacterium abscessus . Cells, 9, 2020
1QP1	KAPPA VARIABLE LIGHT CHAIN 分子名称: BENCE-JONES KAPPA I ANTIBODY BRE (LIGHT CHAIN) 著者 Steinrauf, L.K. 登録日 1999-05-30 公開日 1999-06-17 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Molecular structure of the amyloid-forming protein kappa I Bre. J.Biochem.(Tokyo), 125, 1999
2PN7	Human gamma-glutamyl cyclotransferase 分子名称: human gamma-glutamyl cyclotransferase 著者 Oakley, A.J, Board, P.G. 登録日 2007-04-24 公開日 2007-05-01 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 The identification and structural characterization of C7orf24 as gamma-glutamyl cyclotransferase. An essential enzyme in the gamma-glutamyl cycle. J.Biol.Chem., 283, 2008
1LRU	Crystal Structure of E.coli Peptide Deformylase Complexed with Antibiotic Actinonin 分子名称: ACTINONIN, PEPTIDE DEFORMYLASE, SULFATE ION, ... 著者 Guilloteau, J.-P, Mathieu, M, Giglione, C, Blanc, V, Dupuy, A, Chevrier, M, Gil, P, Famechon, A, Meinnel, T, Mikol, V. 登録日 2002-05-16 公開日 2002-07-24 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The crystal structures of four peptide deformylases bound to the antibiotic actinonin reveal two distinct types: a platform for the structure-based design of antibacterial agents. J.Mol.Biol., 320, 2002
5WUC	Structural basis for conductance through TRIC cation channels 分子名称: SODIUM ION, Uncharacterized protein 著者 Su, M, Gao, F, Mao, Y, Li, D.L, Guo, Y.Z, Wang, X.H, Bruni, R, Kloss, B, Hendrickson, W.A, Chen, Y.H, New York Consortium on Membrane Protein Structure (NYCOMPS) 登録日 2016-12-17 公開日 2017-07-12 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural basis for conductance through TRIC cation channels. Nat Commun, 8, 2017

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