1LRU

Crystal Structure of E.coli Peptide Deformylase Complexed with Antibiotic Actinonin

Summary for 1LRU

Entry DOI	10.2210/pdb1lru/pdb
Related	1LQW 1LQY 1LRY
Descriptor	PEPTIDE DEFORMYLASE, ZINC ION, ACTINONIN, ... (5 entities in total)
Functional Keywords	actinonin, inhibition, polypeptide deformylase, hydrolase
Biological source	Escherichia coli
Total number of polymer chains	3
Total formula weight	59223.59
Authors	Guilloteau, J.-P.,Mathieu, M.,Giglione, C.,Blanc, V.,Dupuy, A.,Chevrier, M.,Gil, P.,Famechon, A.,Meinnel, T.,Mikol, V. (deposition date: 2002-05-16, release date: 2002-07-24, Last modification date: 2024-02-14)
Primary citation	Guilloteau, J.P.,Mathieu, M.,Giglione, C.,Blanc, V.,Dupuy, A.,Chevrier, M.,Gil, P.,Famechon, A.,Meinnel, T.,Mikol, V. The crystal structures of four peptide deformylases bound to the antibiotic actinonin reveal two distinct types: a platform for the structure-based design of antibacterial agents. J.Mol.Biol., 320:951-962, 2002 Cited by PubMed: 12126617 DOI: 10.1016/S0022-2836(02)00549-1 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation