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1JN6
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Crystal Structure of Fab-Estradiol Complexes
分子名称: monoclonal anti-estradiol 10G6D6 Fab heavy chain, monoclonal anti-estradiol 10G6D6 Fab light chain
著者Monnet, C, Bettsworth, F, Stura, E.A, Le Du, M.-H, Menez, R, Derrien, L, Zinn-Justin, S, Gilquin, B, Sibai, G, Battail-Poirot, N, Jolivet, M, Menez, A, Arnaud, M, Ducancel, F, Charbonnier, J.B.
登録日2001-07-23
公開日2002-02-06
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Highly specific anti-estradiol antibodies: structural characterisation and binding diversity.
J.Mol.Biol., 315, 2002
1QQD
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CRYSTAL STRUCTURE OF HLA-CW4, A LIGAND FOR THE KIR2D NATURAL KILLER CELL INHIBITORY RECEPTOR
分子名称: BETA-2 MICROGLOBULIN, HISTOCOMPATIBILITY LEUKOCYTE ANTIGEN (HLA)-CW4 (HEAVY CHAIN), HLA-CW4 SPECIFIC PEPTIDE
著者Fan, Q.R, Wiley, D.C.
登録日1999-06-03
公開日1999-12-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of human histocompatibility leukocyte antigen (HLA)-Cw4, a ligand for the KIR2D natural killer cell inhibitory receptor
J.Exp.Med., 190, 1999
1MCL
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PRINCIPLES AND PITFALLS in DESIGNING SITE DIRECTED PEPTIDE LIGANDS
分子名称: IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN), N-ACETYL-D-HIS-L-PRO-OH
著者Edmundson, A.B, Harris, D.L, Fan, Z.-C, Guddat, L.W.
登録日1993-02-25
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Principles and pitfalls in designing site-directed peptide ligands.
Proteins, 16, 1993
2F74
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Murine MHC class I H-2Db in complex with human b2-microglobulin and LCMV-derived immunodminant peptide gp33
分子名称: Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ...
著者Achour, A, Michaelsson, J, Harris, R.A, Ljunggren, H.G, Karre, K, Schneider, G, Sandalova, T.
登録日2005-11-30
公開日2006-02-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Basis of the Differential Stability and Receptor Specificity of H-2D(b) in Complex with Murine versus Human beta(2)-Microglobulin.
J.Mol.Biol., 356, 2006
1DBJ
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BU of 1dbj by Molmil
MOLECULAR BASIS OF CROSS-REACTIVITY AND THE LIMITS OF ANTIBODY-ANTIGEN COMPLEMENTARITY
分子名称: AETIOCHOLANOLONE, IGG1-KAPPA DB3 FAB (HEAVY CHAIN), IGG1-KAPPA DB3 FAB (LIGHT CHAIN)
著者Arevalo, J.H, Wilson, I.A.
登録日1993-08-24
公開日1994-01-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Molecular basis of crossreactivity and the limits of antibody-antigen complementarity.
Nature, 365, 1993
3QIB
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Crystal structure of the 2B4 TCR in complex with MCC/I-Ek
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2B4 beta chain, DI(HYDROXYETHYL)ETHER, ...
著者Ely, L.K, Newell, E.W, Davis, M.M, Garcia, K.C.
登録日2011-01-26
公開日2011-04-27
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis of specificity and cross-reactivity in T cell receptors specific for cytochrome c-I-E(k).
J.Immunol., 186, 2011
1MCE
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BU of 1mce by Molmil
PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS
分子名称: Immunoglobulin lambda-1 light chain, PEPTIDE N-ACETYL-L-GLN-D-PHE-L-HIS-D-PRO-B-ALA-OH
著者Edmundson, A.B, Harris, D.L, Fan, Z.-C, Guddat, L.W.
登録日1993-02-25
公開日1994-01-31
最終更新日2022-04-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Principles and pitfalls in designing site-directed peptide ligands.
Proteins, 16, 1993
2A1W
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BU of 2a1w by Molmil
Anti-cocaine antibody 7.5.21, crystal form I
分子名称: SULFATE ION, immunoglobulin heavy chain, immunoglobulin light chain kappa
著者Pozharski, E, Hewagama, A, Shanafelt, A, Ringe, D, Petsko, G.A.
登録日2005-06-21
公開日2005-06-28
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Flexibility Of Packing: Four Crystal Forms Of An Anti-Cocaine Antibody 7.5.21
To be Published
1MCF
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BU of 1mcf by Molmil
PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS
分子名称: Immunoglobulin lambda-1 light chain, PEPTIDE N-ACETYL-L-GLN-D-PHE-L-HIS-D-PRO-B-ALA-B-ALA-OH
著者Edmundson, A.B, Harris, D.L, Fan, Z.-C, Guddat, L.W.
登録日1993-02-25
公開日1994-01-31
最終更新日2022-04-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Principles and pitfalls in designing site-directed peptide ligands.
Proteins, 16, 1993
1ZHB
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BU of 1zhb by Molmil
Crystal Structure Of The Murine Class I Major Histocompatibility Complex Of H-2Db, B2-Microglobulin, and a 9-Residue Peptide Derived from rat dopamine beta-monooxigenase
分子名称: 9-mer peptide from Dopamine beta-monooxygenase, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ...
著者Sandalova, T, Michaelsson, J, Harris, R.A, Odeberg, J, Schneider, G, Karre, K, Achour, A.
登録日2005-04-25
公開日2005-06-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A structural basis for CD8+ T cell-dependent recognition of non-homologous peptide ligands: implications for molecular mimicry in autoreactivity
J.Biol.Chem., 280, 2005
1DFB
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BU of 1dfb by Molmil
STRUCTURE OF A HUMAN MONOCLONAL ANTIBODY FAB FRAGMENT AGAINST GP41 OF HUMAN IMMUNODEFICIENCY VIRUS TYPE I
分子名称: IGG1-KAPPA 3D6 FAB (HEAVY CHAIN), IGG1-KAPPA 3D6 FAB (LIGHT CHAIN)
著者He, X.M, Rueker, F, Casale, E, Carter, D.C.
登録日1992-03-27
公開日1993-10-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of a human monoclonal antibody Fab fragment against gp41 of human immunodeficiency virus type 1.
Proc.Natl.Acad.Sci.USA, 89, 1992
2FO4
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BU of 2fo4 by Molmil
Enhanced MHC class I binding and immune responses through anchor modification of the non-canonical tumor associated MUC1-8 peptide
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 8-mer from Mucin-1, ...
著者Lazoura, E, Ramsland, P.A.
登録日2006-01-12
公開日2006-11-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Enhanced major histocompatibility complex class I binding and immune responses through anchor modification of the non-canonical tumour-associated mucin 1-8 peptide
Immunology, 119, 2006
4JFE
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BU of 4jfe by Molmil
Preservation of peptide specificity during TCR-MHC contact dominated affinity enhancement of a melanoma-specific TCR
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Rizkallah, P.J, Cole, D.K, Madura, F, Sewell, A.K.
登録日2013-02-28
公開日2013-05-29
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献T-cell receptor specificity maintained by altered thermodynamics.
J.Biol.Chem., 288, 2013
8EN8
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BU of 8en8 by Molmil
Cross-reactive 3180 TCR recognition of HLA-B*35:01-NP4 epitope from 1972 influenza strain
分子名称: 3180 TCR alpha chain, 3180 TCR beta chain, Beta-2-microglobulin, ...
著者Littler, D.R, Rossjohn, J.
登録日2022-09-29
公開日2024-03-27
実験手法X-RAY DIFFRACTION (2.700012 Å)
主引用文献Molecular determinants of cross-strain influenza A virus recognition by T-cell receptors
To Be Published
4WI3
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BU of 4wi3 by Molmil
Structural mapping of the human IgG1 binding site for FcRn: hu3S193 Fc mutation I253A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region
著者Farrugia, W, Burvenich, I.J.G, Scott, A.M, Ramsland, P.A.
登録日2014-09-25
公開日2015-09-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.703 Å)
主引用文献Structural and functional mapping of human IgG1 binding site for FcRn in vivo using human FcRn transgenic mice
To Be Published
4ONO
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BU of 4ono by Molmil
CD1c in complex with PM (phosphomycoketide)
分子名称: (4R,8S,16S,20R)-4,8,12,16,20-pentamethylheptacosyl dihydrogen phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin/T-cell surface glycoprotein CD1c/T-cell surface glycoprotein CD1b chimeric protein, ...
著者Roy, S, Adams, E.J.
登録日2014-01-28
公開日2014-10-08
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.705 Å)
主引用文献Molecular basis of mycobacterial lipid antigen presentation by CD1c and its recognition by alpha beta T cells.
Proc.Natl.Acad.Sci.USA, 111, 2014
5WES
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BU of 5wes by Molmil
Crystal Structure H2-Dd with disulfide-linked 5mer peptide
分子名称: Beta-2-microglobulin, GLYCINE, H-2 class I histocompatibility antigen, ...
著者Jiang, J.S, Natarajan, K, Boyd, L.F, Margulies, D.H.
登録日2017-07-10
公開日2017-10-18
最終更新日2017-12-13
実験手法X-RAY DIFFRACTION (2.706 Å)
主引用文献Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation.
Science, 358, 2017
3EYU
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BU of 3eyu by Molmil
PFA1 Fab fragment complexed with Ror2(518-525)
分子名称: If kappa light chain, PFA1 Fab Heavy Chain, ROR2(518-525) peptide
著者Gardberg, A.S, Dealwis, C.G.
登録日2008-10-21
公開日2009-05-12
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Structures of Abeta-related peptide--monoclonal antibody complexes.
Biochemistry, 48, 2009
5MEP
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BU of 5mep by Molmil
Human Leukocyte Antigen A02 presenting ILGKFLHWL
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Rizkallah, P.J, Cole, D.K, Lloyd, A, Crowther, M, Sewell, A.K.
登録日2016-11-16
公開日2016-12-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase.
J. Biol. Chem., 292, 2017
6LHH
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BU of 6lhh by Molmil
Crystal structure of chicken 8mer-BF2*1501
分子名称: ARG-ARG-ARG-GLU-GLN-THR-ASP-TYR, Beta-2-microglobulin, MHC class I
著者Liu, Y.J, Xia, C.
登録日2019-12-08
公開日2020-12-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献The Combination of CD8 alpha alpha and Peptide-MHC-I in a Face-to-Face Mode Promotes Chicken gamma delta T Cells Response.
Front Immunol, 11, 2020
1KJ2
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BU of 1kj2 by Molmil
Murine Alloreactive ScFv TCR-Peptide-MHC Class I Molecule Complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Allogeneic H-2Kb MHC Class I Molecule, Beta-2 microglobulin, ...
著者Reiser, J.-B, Gregoire, C, Darnault, C, Mosser, T, Guimezanes, A, Schmitt-Verhulst, A.-M, Fontecilla-Camps, J.C, Mazza, G, Malissen, B, Housset, D.
登録日2001-12-04
公開日2002-03-27
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献A T cell receptor CDR3beta loop undergoes conformational changes of unprecedented magnitude upon binding to a peptide/MHC class I complex.
Immunity, 16, 2002
5YC5
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Crystal structure of human IgG-Fc in complex with aglycan and optimized Fc gamma receptor IIIa
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Immunoglobulin gamma-1 heavy chain, ...
著者Caaveiro, J.M.M, Tamura, H, Tsumoto, K, Kiyoshi, M.
登録日2017-09-06
公開日2018-03-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Assessing the Heterogeneity of the Fc-Glycan of a Therapeutic Antibody Using an engineered Fc gamma Receptor IIIa-Immobilized Column.
Sci Rep, 8, 2018
8F8W
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Crystal structure of Nb.X0 bound to the afucosylated human IgG1 fragment crystal form I
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nb.X0, afucosylated IgG1 fragment
著者Goldgur, Y, Ravetch, J, Gupta, A, Kao, K, Oren, D.
登録日2022-11-22
公開日2023-03-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Mechanism of glycoform specificity and in vivo protection by an anti-afucosylated IgG nanobody.
Nat Commun, 14, 2023
1XGY
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Crystal Structure of Anti-Meta I Rhodopsin Fab Fragment K42-41L
分子名称: K42-41L Fab Heavy Chain, K42-41L Fab Light Chain, Rhodopsin Epitope Mimetic Peptide
著者Piscitelli, C.L, Angel, T.E, Bailey, B.W, Lawerence, C.M.
登録日2004-09-17
公開日2005-09-27
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Equilibrium between metarhodopsin-I and metarhodopsin-II is dependent on the conformation of the third cytoplasmic loop.
J.Biol.Chem., 281, 2006
3QXA
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HLA-DR1 bound with CLIP peptide
分子名称: HLA class II histocompatibility antigen gamma chain peptide, HLA class II histocompatibility antigen, DR alpha chain, ...
著者Painter, C.A, Stern, L.J.
登録日2011-03-01
公開日2011-11-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.712 Å)
主引用文献Conformational lability in the class II MHC 310 helix and adjacent extended strand dictate HLA-DM susceptibility and peptide exchange.
Proc.Natl.Acad.Sci.USA, 108, 2011

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