4ASA
 
 | | The structure of modified benzoquinone ansamycins bound to yeast N- terminal Hsp90 | | 分子名称: | ATP-DEPENDENT MOLECULAR CHAPERONE HSP82, CHLORIDE ION, [(3R,5S,6R,7R,12E)-5,11-dimethoxy-3,7,9,15,19-pentamethyl-6-oxidanyl-16,20,22-tris(oxidanylidene)-21-(prop-2-enylamino)-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl] carbamate | | 著者 | Roe, S.M, Prodromou, C. | | 登録日 | 2012-04-30 | | 公開日 | 2013-04-03 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Synthesis of 19-Substituted Geldanamycins with Altered Conformations and Their Binding to Heat Shock Protein Hsp90.
Nat.Chem., 5, 2013
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1TFS
 | | NMR AND RESTRAINED MOLECULAR DYNAMICS STUDY OF THE THREE-DIMENSIONAL SOLUTION STRUCTURE OF TOXIN FS2, A SPECIFIC BLOCKER OF THE L-TYPE CALCIUM CHANNEL, ISOLATED FROM BLACK MAMBA VENOM | | 分子名称: | TOXIN FS2 | | 著者 | Albrand, J.-P, Blackledge, M.J, Pascaud, F, Hollecker, M, Marion, D. | | 登録日 | 1995-01-26 | | 公開日 | 1995-03-31 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR and restrained molecular dynamics study of the three-dimensional solution structure of toxin FS2, a specific blocker of the L-type calcium channel, isolated from black mamba venom.
Biochemistry, 34, 1995
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7O3C
 | | Murine supercomplex CIII2CIV in the mature unlocked conformation | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ... | | 著者 | Vercellino, I, Sazanov, L.A. | | 登録日 | 2021-04-01 | | 公開日 | 2021-10-13 | | 最終更新日 | 2021-10-27 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structure and assembly of the mammalian mitochondrial supercomplex CIII 2 CIV.
Nature, 598, 2021
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7O37
 | | Murine supercomplex CIII2CIV in the assembled locked conformation | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ... | | 著者 | Vercellino, I, Sazanov, L.A. | | 登録日 | 2021-04-01 | | 公開日 | 2021-10-13 | | 最終更新日 | 2021-10-27 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structure and assembly of the mammalian mitochondrial supercomplex CIII 2 CIV.
Nature, 598, 2021
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7O3E
 | | Murine supercomplex CIII2CIV in the intermediate locked conformation | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ... | | 著者 | Vercellino, I, Sazanov, L.A. | | 登録日 | 2021-04-01 | | 公開日 | 2021-10-13 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structure and assembly of the mammalian mitochondrial supercomplex CIII 2 CIV.
Nature, 598, 2021
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5KY8
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5L0R
 | | human POGLUT1 in complex with Notch1 EGF12 and UDP | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Li, Z, Rini, J.M. | | 登録日 | 2016-07-28 | | 公開日 | 2017-08-09 | | 最終更新日 | 2021-03-24 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural basis of Notch O-glucosylation and O-xylosylation by mammalian protein-O-glucosyltransferase 1 (POGLUT1).
Nat Commun, 8, 2017
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1ZWH
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5UB5
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2YGA
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8CHY
 | | Crystal structure of an 8-repeat consensus TPR superhelix with Zinc. | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CHLORIDE ION, ... | | 著者 | Liutkus, M, Rojas, A.L, Cortajarena, A.L. | | 登録日 | 2023-02-08 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-04-24 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Diverse crystalline protein scaffolds through metal-dependent polymorphism.
Protein Sci., 33, 2024
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8CH0
 | | Crystal structure of an 8-repeat consensus TPR superhelix with Gadolinium. | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Consensus tetratricopeptide repeat protein, ... | | 著者 | Liutkus, M, Rojas, A.L, Cortajarena, A.L. | | 登録日 | 2023-02-06 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-04-24 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Diverse crystalline protein scaffolds through metal-dependent polymorphism.
Protein Sci., 33, 2024
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8CIG
 | | Crystal structure of an 8-repeat consensus TPR superhelix in tris Buffer with Calcium. | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... | | 著者 | Liutkus, M, Rojas, A.L, Cortajarena, A.L. | | 登録日 | 2023-02-09 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-04-24 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Diverse crystalline protein scaffolds through metal-dependent polymorphism.
Protein Sci., 33, 2024
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6CGX
 | | Backbone cyclised conotoxin Vc1.1 mutant - D11A, E14A | | 分子名称: | Alpha-conotoxin Vc1A | | 著者 | Clark, R.J. | | 登録日 | 2018-02-21 | | 公開日 | 2018-05-23 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure-Activity Studies Reveal the Molecular Basis for GABAB-Receptor Mediated Inhibition of High Voltage-Activated Calcium Channels by alpha-Conotoxin Vc1.1.
ACS Chem. Biol., 13, 2018
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1EZR
 | | CRYSTAL STRUCTURE OF NUCLEOSIDE HYDROLASE FROM LEISHMANIA MAJOR | | 分子名称: | CALCIUM ION, NUCLEOSIDE HYDROLASE | | 著者 | Shi, W, Schramm, V.L, Almo, S.C. | | 登録日 | 2000-05-11 | | 公開日 | 2000-05-24 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Nucleoside hydrolase from Leishmania major. Cloning, expression, catalytic properties, transition state inhibitors, and the 2.5-a crystal structure.
J.Biol.Chem., 274, 1999
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4QHR
 | | The structure of alanine racemase from Acinetobacter baumannii | | 分子名称: | Alanine racemase | | 著者 | Davis, E, Scaletti-Hutchinson, E, Nakatani, Y, Krause, K.L. | | 登録日 | 2014-05-29 | | 公開日 | 2015-05-06 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The structure of alanine racemase from Acinetobacter baumannii
ACTA CRYSTALLOGR.,SECT.F, 70, 2014
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7ZOR
 | | Crystal structure of anti-Siglec-15 Fab | | 分子名称: | Anti-siglec15 FAB HC, Anti-siglec15 FAB LC | | 著者 | Lenza, M.P, Oyenarte, I, Jimenez-Barbero, J, Ereno-Orbea, J. | | 登録日 | 2022-04-26 | | 公開日 | 2023-06-28 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3.933 Å) | | 主引用文献 | Structural insights into Siglec-15 reveal glycosylation dependency for its interaction with T cells through integrin CD11b.
Nat Commun, 14, 2023
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7ZOZ
 | | Crystal structure of Siglec-15 in complex with Fab | | 分子名称: | Anti-Siglec 15 Fab HC, Anti-Siglec 15 Fab LC, Sialic acid-binding Ig-like lectin 15 | | 著者 | Lenza, M.P, Oyenarte, I, Jimenez-Barbero, J, Ereno-Orbea, J. | | 登録日 | 2022-04-26 | | 公開日 | 2023-06-28 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.104 Å) | | 主引用文献 | Structural insights into Siglec-15 reveal glycosylation dependency for its interaction with T cells through integrin CD11b.
Nat Commun, 14, 2023
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7ZZ5
 | | Cryo-EM structure of "BC open" conformation of Lactococcus lactis pyruvate carboxylase with acetyl-CoA | | 分子名称: | ACETYL COENZYME *A, BICARBONATE ION, Pyruvate carboxylase | | 著者 | Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M. | | 登録日 | 2022-05-25 | | 公開日 | 2022-10-12 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (2.43 Å) | | 主引用文献 | CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
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7ZZ3
 | | Cryo-EM structure of "BC react" conformation of Lactococcus lactis pyruvate carboxylase with acetyl-CoA | | 分子名称: | ACETYL COENZYME *A, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M. | | 登録日 | 2022-05-25 | | 公開日 | 2022-10-12 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (2.41 Å) | | 主引用文献 | CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
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7ZYZ
 | | Cryo-EM structure of "CT oxa" conformation of Lactococcus lactis pyruvate carboxylase with acetyl-CoA | | 分子名称: | MANGANESE (II) ION, OXALOACETATE ION, Pyruvate carboxylase | | 著者 | Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M. | | 登録日 | 2022-05-25 | | 公開日 | 2022-10-12 | | 最終更新日 | 2022-11-02 | | 実験手法 | ELECTRON MICROSCOPY (2.47 Å) | | 主引用文献 | CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
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7ZZ1
 | | Cryo-EM structure of "CT react" conformation of Lactococcus lactis pyruvate carboxylase with acetyl-CoA | | 分子名称: | BIOTIN, MAGNESIUM ION, MANGANESE (II) ION, ... | | 著者 | Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M. | | 登録日 | 2022-05-25 | | 公開日 | 2022-10-12 | | 最終更新日 | 2022-11-02 | | 実験手法 | ELECTRON MICROSCOPY (2.27 Å) | | 主引用文献 | CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
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7ZZ2
 | | Cryo-EM structure of "CT pyr" conformation of Lactococcus lactis pyruvate carboxylase with acetyl-CoA | | 分子名称: | MAGNESIUM ION, MANGANESE (II) ION, PYRUVIC ACID, ... | | 著者 | Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M. | | 登録日 | 2022-05-25 | | 公開日 | 2022-10-12 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (2.48 Å) | | 主引用文献 | CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
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7ZZ0
 | | Cryo-EM structure of "CT empty" conformation of Lactococcus lactis pyruvate carboxylase with acetyl-CoA | | 分子名称: | MAGNESIUM ION, MANGANESE (II) ION, Pyruvate carboxylase | | 著者 | Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M. | | 登録日 | 2022-05-25 | | 公開日 | 2022-10-12 | | 最終更新日 | 2022-11-02 | | 実験手法 | ELECTRON MICROSCOPY (2.26 Å) | | 主引用文献 | CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
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7ZZ4
 | | Cryo-EM structure of "BC closed" conformation of Lactococcus lactis pyruvate carboxylase with acetyl-CoA | | 分子名称: | ACETYL COENZYME *A, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M. | | 登録日 | 2022-05-25 | | 公開日 | 2022-10-12 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (2.63 Å) | | 主引用文献 | CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
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