human POGLUT1 in complex with human Notch1 EGF12 S458T mutant and UDP

Summary for 5UB5

Related5L0R 5L0S 5L0T 5L0U 5L0V
DescriptorProtein O-glucosyltransferase 1, Neurogenic locus notch homolog protein 1, N-ACETYL-D-GLUCOSAMINE, ... (6 entities in total)
Functional Keywordstransferase, glycosyltransferase, gt-b glucosyltransferase
Biological sourceHomo sapiens (Human)
Cellular locationEndoplasmic reticulum lumen  Q8NBL1
Cell membrane ; Single-pass type I membrane protein . Notch 1 intracellular domain: Nucleus  P46531
Total number of polymer chains2
Total molecular weight47723.96
Li, Z.,Rini, J.M. (deposition date: 2016-12-20, release date: 2017-08-09, Last modification date: 2018-04-04)
Primary citation
Li, Z.,Fischer, M.,Satkunarajah, M.,Zhou, D.,Withers, S.G.,Rini, J.M.
Structural basis of Notch O-glucosylation and O-xylosylation by mammalian protein-O-glucosyltransferase 1 (POGLUT1).
Nat Commun, 8:185-185, 2017
PubMed: 28775322 (PDB entries with the same primary citation)
DOI: 10.1038/s41467-017-00255-7
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.194201.1%3.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution