5UB5
human POGLUT1 in complex with human Notch1 EGF12 S458T mutant and UDP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein O-glucosyltransferase 1 | polymer | 357 | 42077.1 | 1 | UniProt (Q8NBL1) Pfam (PF05686) | Homo sapiens (Human) | CAP10-like 46 kDa protein,hCLP46,KTEL motif-containing protein 1,Myelodysplastic syndromes relative protein,O-glucosyltransferase Rumi homolog,hRumi,Protein O-xylosyltransferase |
| 2 | B (B) | Neurogenic locus notch homolog protein 1 | polymer | 42 | 4539.0 | 1 | UniProt (P46531) Pfam (PF00008) | Homo sapiens (Human) | hN1,Translocation-associated notch protein TAN-1 |
| 3 | C, D, E (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 4 | F (A) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 1 | Chemie (UDP) | |||
| 5 | G (B) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 6 | H, I (A, B) | water | water | 18.0 | 337 | Chemie (HOH) |
Sequence modifications
B: 452 - 491 (UniProt: P46531)
| PDB | External Database | Details |
|---|---|---|
| Gly 450 | - | expression tag |
| Ser 451 | - | expression tag |
| Thr 458 | Ser 458 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 46616.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1107.9 | |
| All* | Total formula weight | 47724.0 |
