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1PPB
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BU of 1ppb by Molmil
THE REFINED 1.9 ANGSTROMS CRYSTAL STRUCTURE OF HUMAN ALPHA-THROMBIN: INTERACTION WITH D-PHE-PRO-ARG CHLOROMETHYLKETONE AND SIGNIFICANCE OF THE TYR-PRO-PRO-TRP INSERTION SEGMENT
分子名称: ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide
著者Bode, W.
登録日1991-10-24
公開日1994-01-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献The refined 1.9 A crystal structure of human alpha-thrombin: interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segment.
EMBO J., 8, 1989
1P10
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BU of 1p10 by Molmil
STRUCTURAL PLASTICITY AS A DETERMINANT OF ENZYME SPECIFICITY. CREATING BROADLY SPECIFIC PROTEASES
分子名称: ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-VALINE BORONIC ACID INHIBITOR, SULFATE ION
著者Bone, R, Agard, D.A.
登録日1989-04-24
公開日1990-04-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural plasticity broadens the specificity of an engineered protease.
Nature, 339, 1989
3HAF
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BU of 3haf by Molmil
Human prion protein variant V129 domain swapped dimer
分子名称: CADMIUM ION, CHLORIDE ION, Major prion protein
著者Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C.
登録日2009-05-01
公開日2010-01-12
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
3HAK
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BU of 3hak by Molmil
Human prion protein variant V129
分子名称: Major prion protein
著者Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C.
登録日2009-05-01
公開日2010-01-12
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
3HEQ
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BU of 3heq by Molmil
Human prion protein variant D178N with M129
分子名称: CADMIUM ION, Major prion protein
著者Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C.
登録日2009-05-10
公開日2010-01-12
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
3HES
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BU of 3hes by Molmil
Human prion protein variant F198S with M129
分子名称: CADMIUM ION, Major prion protein
著者Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C.
登録日2009-05-10
公開日2010-01-12
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
5ER2
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BU of 5er2 by Molmil
High-resolution X-ray diffraction study of the complex between endothiapepsin and an oligopeptide inhibitor. the analysis of the inhibitor binding and description of the rigid body shift in the enzyme
分子名称: 6-ammonio-N-{[(2R,3R)-3-{[N-(tert-butoxycarbonyl)-L-phenylalanyl-3-(1H-imidazol-3-ium-4-yl)-L-alanyl]amino}-4-cyclohexyl-2-hydroxybutyl](2-methylpropyl)carbamoyl}-L-norleucyl-L-phenylalanine, ENDOTHIAPEPSIN
著者Sali, A, Veerapandian, B, Cooper, J.B, Foundling, S.I, Hoover, D.J, Blundell, T.L.
登録日1991-01-02
公開日1991-04-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献High-resolution X-ray diffraction study of the complex between endothiapepsin and an oligopeptide inhibitor: the analysis of the inhibitor binding and description of the rigid body shift in the enzyme.
EMBO J., 8, 1989
3WON
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BU of 3won by Molmil
Crystal structure of the DAP BII dipeptide complex III
分子名称: GLYCEROL, TYROSINE, VALINE, ...
著者Sakamoto, Y, Suzuki, Y, Iizuka, I, Tateoka, C, Roppongi, S, Fujimoto, M, Nonaka, T, Ogasawara, W, Tanaka, N.
登録日2013-12-29
公開日2014-09-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献S46 peptidases are the first exopeptidases to be members of clan PA
SCI REP, 4, 2014
3RY6
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BU of 3ry6 by Molmil
Complex of fcgammariia (CD32) and the FC of human IGG1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Ig gamma-1 chain C region, ...
著者Ramsland, P.A, Farrugia, W, Scott, A.M, Hogarth, P.M.
登録日2011-05-11
公開日2011-08-31
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structural Basis for Fc{gamma}RIIa Recognition of Human IgG and Formation of Inflammatory Signaling Complexes.
J.Immunol., 187, 2011
3WOL
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BU of 3wol by Molmil
Crystal structure of the DAP BII dipeptide complex I
分子名称: GLYCEROL, TYROSINE, VALINE, ...
著者Sakamoto, Y, Suzuki, Y, Iizuka, I, Tateoka, C, Roppongi, S, Fujimoto, M, Nonaka, T, Ogasawara, W, Tanaka, N.
登録日2013-12-29
公開日2014-09-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献S46 peptidases are the first exopeptidases to be members of clan PA
SCI REP, 4, 2014
3ZPK
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BU of 3zpk by Molmil
Atomic-resolution structure of a quadruplet cross-beta amyloid fibril.
分子名称: TRANSTHYRETIN
著者Fitzpatrick, A.W.P, Debelouchina, G.T, Bayro, M.J, Clare, D.K, Caporini, M.A, Bajaj, V.S, Jaroniec, C.P, Wang, L, Ladizhansky, V, Muller, S.A, MacPhee, C.E, Waudby, C.A, Mott, H.R, de Simone, A, Knowles, T.P.J, Saibil, H.R, Vendruscolo, M, Orlova, E.V, Griffin, R.G, Dobson, C.M.
登録日2013-02-28
公開日2013-12-04
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY, SOLID-STATE NMR
主引用文献Atomic Structure and Hierarchical Assembly of a Cross-Beta Amyloid Fibril.
Proc.Natl.Acad.Sci.USA, 110, 2013
8FGX
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BU of 8fgx by Molmil
Cryo-EM structure of the STAR-0215 Fab in complex with active human plasma kallikrein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Plasma kallikrein light chain, STAR-0215 Heavy chain, ...
著者Fuller, J.R, Biris, N, Bista, P.
登録日2022-12-13
公開日2023-09-06
最終更新日2023-10-25
実験手法ELECTRON MICROSCOPY (2.62 Å)
主引用文献STAR-0215 is a Novel, Long-Acting Monoclonal Antibody Inhibitor of Plasma Kallikrein for the Potential Treatment of Hereditary Angioedema.
J.Pharmacol.Exp.Ther., 387, 2023
3WOO
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BU of 3woo by Molmil
Crystal structure of the DAP BII hexapeptide complex I
分子名称: Angiotensin II, GLYCEROL, ZINC ION, ...
著者Sakamoto, Y, Suzuki, Y, Iizuka, I, Tateoka, C, Roppongi, S, Fujimoto, M, Nonaka, T, Ogasawara, W, Tanaka, N.
登録日2013-12-29
公開日2014-09-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献S46 peptidases are the first exopeptidases to be members of clan PA
SCI REP, 4, 2014
3WOK
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BU of 3wok by Molmil
Crystal structure of the DAP BII (Space)
分子名称: GLYCEROL, ZINC ION, dipeptidyl aminopeptidase BII
著者Sakamoto, Y, Suzuki, Y, Iizuka, I, Tateoka, C, Roppongi, S, Fujimoto, M, Nonaka, T, Ogasawara, W, Tanaka, N.
登録日2013-12-29
公開日2014-09-03
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献S46 peptidases are the first exopeptidases to be members of clan PA
SCI REP, 4, 2014
3WOJ
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BU of 3woj by Molmil
Crystal structure of the DAP BII
分子名称: GLYCEROL, ZINC ION, dipeptidyl aminopeptidase BII
著者Sakamoto, Y, Suzuki, Y, Iizuka, I, Tateoka, C, Roppongi, S, Fujimoto, M, Nonaka, T, Ogasawara, W, Tanaka, N.
登録日2013-12-29
公開日2014-09-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献S46 peptidases are the first exopeptidases to be members of clan PA
SCI REP, 4, 2014
3WOP
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BU of 3wop by Molmil
Crystal structure of the DAP BII hexapeptide complex II
分子名称: Angiotensin IV, GLYCEROL, ZINC ION, ...
著者Sakamoto, Y, Suzuki, Y, Iizuka, I, Tateoka, C, Roppongi, S, Fujimoto, M, Nonaka, T, Ogasawara, W, Tanaka, N.
登録日2013-12-29
公開日2014-09-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献S46 peptidases are the first exopeptidases to be members of clan PA
SCI REP, 4, 2014
3WOQ
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BU of 3woq by Molmil
Crystal structure of the DAP BII hexapeptide complex III
分子名称: Angiotensin IV, GLYCEROL, ZINC ION, ...
著者Sakamoto, Y, Suzuki, Y, Iizuka, I, Tateoka, C, Roppongi, S, Fujimoto, M, Nonaka, T, Ogasawara, W, Tanaka, N.
登録日2013-12-29
公開日2014-09-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献S46 peptidases are the first exopeptidases to be members of clan PA
SCI REP, 4, 2014
5ER1
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BU of 5er1 by Molmil
A rational approach to the design of antihypertensives. X-ray studies of complexes between aspartic proteinases and aminoalcohol renin inhibitors
分子名称: ENDOTHIAPEPSIN, methyl N-[(2S,3S)-3-amino-2-hydroxy-5-methylhexyl]-L-valyl-L-isoleucyl-L-phenylalaninate
著者Cooper, J.B, Foundling, S.I, Blundell, T.L.
登録日1990-11-07
公開日1991-01-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A Rational Approach to the Design of Antihypertensives. X-Ray Studies of Complexes between Aspartic Proteinases and Aminoalcohol Renin Inhibitors
Topics in Medicinal Chemistry, 1988
3ZUE
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BU of 3zue by Molmil
Rabbit Hemorrhagic Disease Virus (RHDV)capsid protein
分子名称: CAPSID STRUCTURAL PROTEIN VP60
著者Luque, D, Gonzalez, J.M, Gomez-Blanco, J, Marabini, R, Chichon, J, Mena, I, Angulo, I, Carrascosa, J.L, Verdaguer, N, Trus, B.L, Barcena, J, Caston, J.R.
登録日2011-07-18
公開日2012-05-23
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (10.3 Å)
主引用文献Epitope Insertion at the N-Terminal Molecular Switch of the Rabbit Hemorrhagic Disease Virus T=3 Capsid Protein Leads to Larger T=4 Capsids.
J.Virol., 86, 2012
3WOR
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BU of 3wor by Molmil
Crystal structure of the DAP BII octapeptide complex
分子名称: Angiotensin II, GLYCEROL, ZINC ION, ...
著者Sakamoto, Y, Suzuki, Y, Iizuka, I, Tateoka, C, Roppongi, S, Fujimoto, M, Nonaka, T, Ogasawara, W, Tanaka, N.
登録日2013-12-29
公開日2014-09-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献S46 peptidases are the first exopeptidases to be members of clan PA
SCI REP, 4, 2014
3TJY
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BU of 3tjy by Molmil
Structure of the Pto-binding domain of HopPmaL generated by limited chymotrypsin digestion
分子名称: CHLORIDE ION, Effector protein hopAB3, SULFATE ION
著者Singer, A.U, Stein, A, Xu, X, Cui, H, Joachimiak, A, Edwards, A.M, Savchenko, A, Midwest Center for Structural Genomics (MCSG)
登録日2011-08-25
公開日2011-09-14
最終更新日2013-01-09
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural analysis of HopPmaL reveals the presence of a second adaptor domain common to the HopAB family of Pseudomonas syringae type III effectors.
Biochemistry, 51, 2012
3WOM
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BU of 3wom by Molmil
Crystal structure of the DAP BII dipeptide complex II
分子名称: GLYCEROL, TYROSINE, VALINE, ...
著者Sakamoto, Y, Suzuki, Y, Iizuka, I, Tateoka, C, Roppongi, S, Fujimoto, M, Nonaka, T, Ogasawara, W, Tanaka, N.
登録日2013-12-29
公開日2014-09-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献S46 peptidases are the first exopeptidases to be members of clan PA
SCI REP, 4, 2014
3WOI
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BU of 3woi by Molmil
Crystal structure of the DAP BII (S657A)
分子名称: GLYCEROL, ZINC ION, dipeptidyl aminopeptidase BII
著者Sakamoto, Y, Suzuki, Y, Iizuka, I, Tateoka, C, Roppongi, S, Fujimoto, M, Nonaka, T, Ogasawara, W, Tanaka, N.
登録日2013-12-29
公開日2014-09-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献S46 peptidases are the first exopeptidases to be members of clan PA
SCI REP, 4, 2014
8CDB
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BU of 8cdb by Molmil
Proulilysin E229A structure
分子名称: CALCIUM ION, Ulilysin, ZINC ION
著者Rodriguez-Banqueri, A, Eckhard, U, Gomis-Ruth, F.X.
登録日2023-01-30
公開日2023-03-22
最終更新日2023-03-29
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献Structural insights into latency of the metallopeptidase ulilysin (lysargiNase) and its unexpected inhibition by a sulfonyl-fluoride inhibitor of serine peptidases.
Dalton Trans, 52, 2023
8C4A
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BU of 8c4a by Molmil
Structural and interactional insights into the glideosome-associated connector from Toxoplasma gondii
分子名称: Putative anonymous antigen-1
著者Kumar, A, Morgan, R.M.L, Matthews, S.J.
登録日2023-01-03
公開日2023-07-19
実験手法X-RAY DIFFRACTION (2.675 Å)
主引用文献Structural and regulatory insights into the glideosome-associated connector from Toxoplasma gondii.
Elife, 12, 2023

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