PDB: 5425 件ウェブページステータス検索Chemie searchBIRD

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2ZO2	Mouse NP95 SRA domain non-specific DNA complex 分子名称: DNA (5'-D(*DAP*DAP*DCP*DTP*DGP*DCP*DGP*DCP*DAP*DGP*DTP*DT)-3'), E3 ubiquitin-protein ligase UHRF1, PHOSPHATE ION 著者 Hashimoto, H, Horton, J.R, Cheng, X. 登録日 2008-05-05 公開日 2008-09-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.09 Å) 主引用文献 The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix Nature, 455, 2008
3ODR	Crystal Structure of the N-terminal Domain of Human Symplekin 分子名称: 1,2-ETHANEDIOL, Symplekin 著者 Tong, L, Xiang, K. 登録日 2010-08-11 公開日 2010-10-06 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex. Nature, 467, 2010
5TIJ	Structure of Human Enolase 2 with ((3S,5S)-1,5-dihydroxy-3-methyl-2-oxopyrrolidin-3-yl)phosphonate (purified enantiomer) 分子名称: ((3S,5S)-1,5-dihydroxy-3-methyl-2-oxopyrrolidin-3-yl)phosphonic acid, Gamma-enolase, MAGNESIUM ION 著者 Leonard, P.G, Muller, F.L. 登録日 2016-10-03 公開日 2017-10-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.634 Å) 主引用文献 Eradication of ENO1-deleted Glioblastoma through Collateral Lethality Biorxiv, 2019
1ZXM	Human Topo IIa ATPase/AMP-PNP 分子名称: DNA topoisomerase II, alpha isozyme, MAGNESIUM ION, ... 著者 Wei, H, Ruthenburg, A.J, Bechis, S.K, Verdine, G.L. 登録日 2005-06-08 公開日 2005-08-23 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Nucleotide-dependent Domain Movement in the ATPase Domain of a Human Type IIA DNA Topoisomerase. J.Biol.Chem., 280, 2005
2Z5U	Crystal structure of Lysine-specific histone demethylase 1 分子名称: FAD-trans-2-Phenylcyclopropylamine Adduct, Lysine-specific histone demethylase 1 著者 Mimasu, S, Sengoku, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-07-17 公開日 2008-04-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal structure of histone demethylase LSD1 and tranylcypromine at 2.25 A Biochem.Biophys.Res.Commun., 366, 2008
1HG2	CALM-N N-terminal domain of clathrin assembly lymphoid myeloid leukaemia protein, Inositol(4,5)P2 complex 分子名称: CLATHRIN ASSEMBLY PROTEIN SHORT FORM, D-MYO-INOSITOL-4,5-BISPHOSPHATE 著者 Ford, M.G.J, Evans, P.R, McMahon, H.T. 登録日 2000-12-12 公開日 2001-02-12 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Simultaneous Binding of Ptdins(4,5)P2 and Clathrin by Ap180 in the Nucleation of Clathrin Lattices on Membranes Science, 291, 2001
3MAX	Crystal Structure of Human HDAC2 complexed with an N-(2-aminophenyl)benzamide 分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CALCIUM ION, Histone deacetylase 2, ... 著者 Skene, R.J, Jennings, A.J. 登録日 2010-03-24 公開日 2010-04-28 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Exploration of the HDAC2 foot pocket: Synthesis and SAR of substituted N-(2-aminophenyl)benzamides. Bioorg.Med.Chem.Lett., 20, 2010
5U28	BRD4 first bromodomain (BD1) in complex with dual PI3 kinase inhibitor SF2523 分子名称: 3-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(morpholin-4-yl)-7H-thieno[3,2-b]pyran-7-one, Bromodomain-containing protein 4, DI(HYDROXYETHYL)ETHER, ... 著者 Andrews, F.H, Kutateladze, T.G. 登録日 2016-11-30 公開日 2017-02-08 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.798 Å) 主引用文献 Dual-activity PI3K-BRD4 inhibitor for the orthogonal inhibition of MYC to block tumor growth and metastasis. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
2ZKG	Crystal structure of unliganded SRA domain of mouse Np95 分子名称: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase UHRF1 著者 Arita, K, Ariyoshi, M, Tochio, H, Nakamura, Y, Shirakawa, M. 登録日 2008-03-19 公開日 2008-09-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism Nature, 455, 2008
1H6K	nuclear Cap Binding Complex 分子名称: 20 KDA NUCLEAR CAP BINDING PROTEIN, CBP80 著者 Mazza, C, Ohno, M, Segref, A, Mattaj, I.W, Cusack, S. 登録日 2001-06-18 公開日 2001-09-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of the Human Nuclear CAP Binding Complex Mol.Cell, 8, 2001
1ZNQ	Crystal Structure of Human Liver GAPDH 分子名称: Glyceraldehyde-3-phosphate dehydrogenase, liver, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Ismail, S.A, Park, H.W. 登録日 2005-05-11 公開日 2005-05-24 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structure Analysis of Human liver GAPDH To be Published
1E32	Structure of the N-Terminal domain and the D1 AAA domain of membrane fusion ATPase p97 分子名称: ADENOSINE-5'-DIPHOSPHATE, P97 著者 Zhang, X, Shaw, A, Bates, P.A, Gorman, M.A, Kondo, H, Dokurno, P, Leonard M, G, Sternberg, J.E, Freemont, P.S. 登録日 2000-06-05 公開日 2001-05-31 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure of the Aaa ATPase P97 Mol.Cell, 6, 2000
1YUW	crystal structure of bovine hsc70(aa1-554)E213A/D214A mutant 分子名称: Heat shock cognate 71 kDa protein 著者 Jiang, J, Lafer, E.M, Prasad, K, Sousa, R. 登録日 2005-02-14 公開日 2005-10-04 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis of interdomain communication in the Hsc70 chaperone Mol.Cell, 20, 2005
5U2E	BRD4 first bromodomain (BD1) in complex with dual PI3 kinase (PI3K) inhibitor SF2535 分子名称: Bromodomain-containing protein 4, ethyl 4-[5-(morpholin-4-yl)-7-oxo-7H-thieno[3,2-b]pyran-3-yl]benzoate 著者 Andrews, F.H, Kutateladze, T.G. 登録日 2016-11-30 公開日 2017-02-08 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.991 Å) 主引用文献 Dual-activity PI3K-BRD4 inhibitor for the orthogonal inhibition of MYC to block tumor growth and metastasis. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1UPW	Crystal structure of the human Liver X receptor beta ligand binding domain in complex with a synthetic agonist 分子名称: N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE, OXYSTEROLS RECEPTOR LXR-BETA 著者 Hoerer, S, Schmid, A, Heckel, A, Budzinski, R.M, Nar, H. 登録日 2003-10-13 公開日 2004-10-20 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure of the Human Liver X Receptor Beta Ligand-Binding Domain in Complex with a Synthetic Agonist J.Mol.Biol., 334, 2003
2ZKD	Crystal structure of the SRA domain of mouse Np95 in complex with hemi-methylated CpG DNA 分子名称: 1,2-ETHANEDIOL, ACETATE ION, DNA (5'-D(*DCP*DTP*DAP*DCP*DCP*DGP*DGP*DAP*DTP*DTP*DGP*DC)-3'), ... 著者 Arita, K, Ariyoshi, M, Tochio, H, Nakamura, Y, Shirakawa, M. 登録日 2008-03-19 公開日 2008-09-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism Nature, 455, 2008
1ZAL	Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with partially disordered tagatose-1,6-bisphosphate, a weak competitive inhibitor 分子名称: Fructose-bisphosphate aldolase A, PHOSPHATE ION 著者 St-Jean, M, Lafrance-Vanasse, J, Liotard, B, Sygusch, J. 登録日 2005-04-06 公開日 2005-05-10 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 High Resolution Reaction Intermediates of Rabbit Muscle Fructose-1,6-bisphosphate Aldolase: substrate cleavage and induced fit. J.Biol.Chem., 280, 2005
5TSO	CRYSTAL STRUCTURE OF GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE FROM PIG MUSCLE COMPLEXED WITH ORTHOPHENANTHROLINE AT 1.90 ANGSTROM RESOLUTION 分子名称: 1,10-PHENANTHROLINE, GLYCEROL, Glyceraldehyde-3-phosphate dehydrogenase, ... 著者 Dimova, M, Devedjiev, Y.D. 登録日 2016-10-30 公開日 2017-05-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Novel Enhancer Binding Site Found In Bacteria And Eukaryota But Not In Archea. To Be Published
1DT9	THE CRYSTAL STRUCTURE OF HUMAN EUKARYOTIC RELEASE FACTOR ERF1-MECHANISM OF STOP CODON RECOGNITION AND PEPTIDYL-TRNA HYDROLYSIS 分子名称: PROTEIN (EUKARYOTIC PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1) 著者 Frolova, L. 登録日 2000-01-12 公開日 2000-02-02 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The crystal structure of human eukaryotic release factor eRF1--mechanism of stop codon recognition and peptidyl-tRNA hydrolysis. Cell(Cambridge,Mass.), 100, 2000
3N5E	Crystal Structure of human thymidylate synthase bound to a peptide inhibitor 分子名称: SULFATE ION, Synthetic peptide LR, Thymidylate synthase 著者 Pozzi, C, Cardinale, D, Guaitoli, G, Tondi, D, Luciani, R, Myllykallio, H, Ferrari, S, Costi, M.P, Mangani, S. 登録日 2010-05-25 公開日 2011-06-08 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Protein-protein interface-binding peptides inhibit the cancer therapy target human thymidylate synthase. Proc.Natl.Acad.Sci.USA, 108, 2011
3C5R	Crystal Structure of the BARD1 Ankyrin Repeat Domain and Its Functional Consequences 分子名称: BRCA1-associated RING domain protein 1 著者 Fox III, D, Le Trong, I, Stenkamp, R.E, Klevit, R.E. 登録日 2008-02-01 公開日 2008-05-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of the BARD1 Ankyrin Repeat Domain and Its Functional Consequences. J.Biol.Chem., 283, 2008
5UWR	Crystal Structure of CDC7 NES Peptide (extended) in complex with CRM1-Ran-RanBP1 分子名称: CHLORIDE ION, Cell division cycle 7-related protein kinase, Exportin-1, ... 著者 Fung, H.Y.J, Chook, Y.M. 登録日 2017-02-21 公開日 2017-03-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals. Elife, 6, 2017
1H6O	Dimerisation domain from human TRF1 分子名称: TELOMERIC REPEAT BINDING FACTOR 1 著者 Fairall, L, Chapman, L, Rhodes, D. 登録日 2001-06-20 公開日 2001-09-05 最終更新日 2024-04-24 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure of the TRFH dimerization domain of the human telomeric proteins TRF1 and TRF2. Mol.Cell, 8, 2001
5V3O	Cereblon in complex with DDB1 and CC-220 分子名称: (3S)-3-[4-({4-[(morpholin-4-yl)methyl]phenyl}methoxy)-1-oxo-1,3-dihydro-2H-isoindol-2-yl]piperidine-2,6-dione, DNA damage-binding protein 1, Protein cereblon, ... 著者 Matyskiela, M, Pagarigan, B, Chamberlain, P. 登録日 2017-03-07 公開日 2017-05-03 最終更新日 2018-02-07 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos. J. Med. Chem., 61, 2018
1XPA	SOLUTION STRUCTURE OF THE DNA-AND RPA-BINDING DOMAIN OF THE HUMAN REPAIR FACTOR XPA, NMR, 1 STRUCTURE 分子名称: XPA, ZINC ION 著者 Ikegami, T, Kuraoka, I, Saijo, M, Kodo, N, Kyogoku, Y, Morikawa, K, Tanaka, K, Shirakawa, M. 登録日 1998-07-06 公開日 1999-07-22 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure of the DNA- and RPA-binding domain of the human repair factor XPA. Nat.Struct.Biol., 5, 1998

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