1ZXM
Human Topo IIa ATPase/AMP-PNP
Summary for 1ZXM
Entry DOI | 10.2210/pdb1zxm/pdb |
Related | 1ZXN |
Descriptor | DNA topoisomerase II, alpha isozyme, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (4 entities in total) |
Functional Keywords | ghkl nucleotide-binding fold, isomerase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P11388 |
Total number of polymer chains | 2 |
Total formula weight | 92382.07 |
Authors | Wei, H.,Ruthenburg, A.J.,Bechis, S.K.,Verdine, G.L. (deposition date: 2005-06-08, release date: 2005-08-23, Last modification date: 2024-02-14) |
Primary citation | Wei, H.,Ruthenburg, A.J.,Bechis, S.K.,Verdine, G.L. Nucleotide-dependent Domain Movement in the ATPase Domain of a Human Type IIA DNA Topoisomerase. J.Biol.Chem., 280:37041-37047, 2005 Cited by PubMed: 16100112DOI: 10.1074/jbc.M506520200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.87 Å) |
Structure validation
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