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1ZXM

Human Topo IIa ATPase/AMP-PNP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
DNA topoisomerase II, alpha isozymepolymer40045660.52UniProt (P11388)
Pfam (PF02518)
Pfam (PF00204)
Homo sapiens (human)Topo IIa ATPase
2C, E
(A, B)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
3D, F
(A, B)
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTERnon-polymer506.22Chemie (ANP)
4G, H
(A, B)
waterwater18.0528Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight91321.1
Non-Polymers*Number of molecules4
Total formula weight1061.0
All*Total formula weight92382.1
*Water molecules are not included.

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PDB entries from 2026-01-21

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