8JDM
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![BU of 8jdm by Molmil](/molmil-images/mine/8jdm) | Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (rotated state) | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | 登録日 | 2023-05-14 | 公開日 | 2023-12-06 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.67 Å) | 主引用文献 | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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8JDL
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![BU of 8jdl by Molmil](/molmil-images/mine/8jdl) | Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (non-rotated state) | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | 登録日 | 2023-05-14 | 公開日 | 2023-12-06 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.42 Å) | 主引用文献 | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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8JDJ
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![BU of 8jdj by Molmil](/molmil-images/mine/8jdj) | Structure of the Human cytoplasmic Ribosome with human tRNA Asp(Q34) and mRNA(GAU) | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | 登録日 | 2023-05-14 | 公開日 | 2023-12-06 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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8JDK
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![BU of 8jdk by Molmil](/molmil-images/mine/8jdk) | Structure of the Human cytoplasmic Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU) | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | 登録日 | 2023-05-14 | 公開日 | 2023-12-06 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.26 Å) | 主引用文献 | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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8IFE
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![BU of 8ife by Molmil](/molmil-images/mine/8ife) | Arbekacin-added human 80S ribosome | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T. | 登録日 | 2023-02-17 | 公開日 | 2024-02-14 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.57 Å) | 主引用文献 | Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside. J.Biochem., 175, 2024
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8IP8
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![BU of 8ip8 by Molmil](/molmil-images/mine/8ip8) | Wheat 80S ribosome stalled on AUG-Stop boron dependently | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein eL8, 40S ribosomal protein eS1, ... | 著者 | Yokoyama, T, Tanaka, M, Saito, H, Nishimoto, M, Tsuda, K, Sotta, N, Shigematsu, H, Shirouzu, M, Iwasaki, S, Ito, T, Fujiwara, T. | 登録日 | 2023-03-14 | 公開日 | 2024-02-21 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Boric acid intercepts 80S ribosome migration from AUG-stop by stabilizing eRF1. Nat.Chem.Biol., 20, 2024
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8I7J
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![BU of 8i7j by Molmil](/molmil-images/mine/8i7j) | |
8I7V
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![BU of 8i7v by Molmil](/molmil-images/mine/8i7v) | Cryo-EM structure of Acipimox bound human hydroxy-carboxylic acid receptor 2 in complex with Gi heterotrimer | 分子名称: | 5-methyl-4-oxidanyl-pyrazin-4-ium-2-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Park, J.H, Ishimoto, N, Park, S.Y. | 登録日 | 2023-02-02 | 公開日 | 2024-02-07 | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | 主引用文献 | Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2. Nat Commun, 14, 2023
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8IED
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![BU of 8ied by Molmil](/molmil-images/mine/8ied) | Cryo-EM structure of GPR156-miniGo-scFv16 complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(o) subunit alpha, ... | 著者 | Shin, J, Park, J, Cho, Y. | 登録日 | 2023-02-15 | 公開日 | 2024-02-14 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.33 Å) | 主引用文献 | Constitutive activation mechanism of a class C GPCR. Nat.Struct.Mol.Biol., 31, 2024
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8IFD
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![BU of 8ifd by Molmil](/molmil-images/mine/8ifd) | Dibekacin-added human 80S ribosome | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T. | 登録日 | 2023-02-17 | 公開日 | 2024-02-14 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.59 Å) | 主引用文献 | Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside. J.Biochem., 175, 2024
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8P94
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![BU of 8p94 by Molmil](/molmil-images/mine/8p94) | |
8OZ0
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![BU of 8oz0 by Molmil](/molmil-images/mine/8oz0) | Structure of a human 48S translation initiation complex with eIF4F and eIF4A | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Brito Querido, J, Sokabe, M, Diaz-Lopez, I, Gordiyenko, Y, Fraser, C.S, Ramakrishnan, V. | 登録日 | 2023-05-06 | 公開日 | 2024-02-07 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | The structure of a human translation initiation complex reveals two independent roles for the helicase eIF4A. Nat.Struct.Mol.Biol., 31, 2024
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8OVE
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![BU of 8ove by Molmil](/molmil-images/mine/8ove) | |
8OVA
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![BU of 8ova by Molmil](/molmil-images/mine/8ova) | |
8OTZ
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![BU of 8otz by Molmil](/molmil-images/mine/8otz) | 48-nm repeat of the native axonemal doublet microtubule from bovine sperm | 分子名称: | ATP6V1F neighbor, CFAP97 domain containing 1, Chromosome 13 C20orf85 homolog, ... | 著者 | Leung, M.R, Zeng, J, Zhang, R, Zeev-Ben-Mordehai, T. | 登録日 | 2023-04-21 | 公開日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural specializations of the sperm tail. Cell, 186, 2023
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8P03
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![BU of 8p03 by Molmil](/molmil-images/mine/8p03) | 48S late-stage initiation complex with m6A mRNA | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | 著者 | Guca, E, Lima, L.H.F, Boissier, F, Hashem, Y. | 登録日 | 2023-05-09 | 公開日 | 2024-03-20 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | 主引用文献 | N 6 -methyladenosine in 5' UTR does not promote translation initiation. Mol.Cell, 84, 2024
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8P09
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![BU of 8p09 by Molmil](/molmil-images/mine/8p09) | 48S late-stage initiation complex with non methylated mRNA | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | 著者 | Guca, E, Lima, L.H.F, Boissier, F, Hashem, Y. | 登録日 | 2023-05-09 | 公開日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | N 6 -methyladenosine in 5' UTR does not promote translation initiation. Mol.Cell, 84, 2024
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8OVJ
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8PKM
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![BU of 8pkm by Molmil](/molmil-images/mine/8pkm) | Befiradol-bound serotonin 5-HT1A receptor - Gi Protein Complex | 分子名称: | (2R)-1-(heptadecanoyloxy)-3-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, (3-chloranyl-4-fluoranyl-phenyl)-[4-fluoranyl-4-[[(5-methylpyridin-2-yl)methylamino]methyl]piperidin-1-yl]methanone, 5-hydroxytryptamine receptor 1A, ... | 著者 | Schneider, J, Gmeiner, P, Hove, T.T, Rasmussen, T, Boettcher, B. | 登録日 | 2023-06-27 | 公開日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Discovery of a functionally selective serotonin 1A receptor agonist
for the treatment of pain To Be Published
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8PJK
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![BU of 8pjk by Molmil](/molmil-images/mine/8pjk) | ST171-bound serotonin 5-HT1A receptor - Gi Protein Complex | 分子名称: | (2R)-1-(heptadecanoyloxy)-3-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, 5-hydroxytryptamine receptor 1A, 6-[3-[2-(2-methoxyphenoxy)ethylamino]propoxy]-4~{H}-1,4-benzoxazin-3-one, ... | 著者 | Schneider, J, Gmeiner, P, Rasmussen, T, Boettcher, B. | 登録日 | 2023-06-23 | 公開日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Discovery of a functionally selective serotonin 1A receptor agonist
for the treatment of pain To Be Published
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8PM2
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![BU of 8pm2 by Molmil](/molmil-images/mine/8pm2) | Structure of the murine trace amine-associated receptor TAAR7f bound to N,N-dimethylcyclohexylamine (DMCH) in complex with mini-Gs trimeric G protein | 分子名称: | CHOLESTEROL HEMISUCCINATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Gusach, A, Lee, Y, Edwards, P.C, Huang, F, Weyand, S.N, Tate, C.G. | 登録日 | 2023-06-28 | 公開日 | 2023-08-09 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | 主引用文献 | Molecular recognition of an aversive odorant by the murine trace amine-associated receptor TAAR7f. Biorxiv, 2023
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8XJK
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![BU of 8xjk by Molmil](/molmil-images/mine/8xjk) | Cloprosetnol bound Prostaglandin F2-alpha receptor-Gq Protein Complex | 分子名称: | (~{Z})-7-[(1~{R},2~{R},3~{R},5~{S})-2-[(~{E},3~{R})-4-(3-chloranylphenoxy)-3-oxidanyl-but-1-enyl]-3,5-bis(oxidanyl)cyclopentyl]hept-5-enoic acid, Antibody fragment scFv16, Engineered miniGq, ... | 著者 | Zhang, X, Li, X, Liu, G, Gong, W. | 登録日 | 2023-12-21 | 公開日 | 2024-02-28 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (2.63 Å) | 主引用文献 | Structural basis for ligand recognition and activation of the prostanoid receptors. Cell Rep, 43, 2024
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8UO1
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![BU of 8uo1 by Molmil](/molmil-images/mine/8uo1) | CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class Q) | 分子名称: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Papasergi-Scott, M.M, Skiniotis, G. | 登録日 | 2023-10-19 | 公開日 | 2024-03-06 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
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8WAK
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![BU of 8wak by Molmil](/molmil-images/mine/8wak) | Structure of transcribing complex 2 (TC2), the initially transcribing complex with Pol II positioned 2nt downstream of TSS. | 分子名称: | Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... | 著者 | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | 登録日 | 2023-09-07 | 公開日 | 2023-12-06 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (5.47 Å) | 主引用文献 | Structural visualization of transcription initiation in action. Science, 382, 2023
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8YRG
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![BU of 8yrg by Molmil](/molmil-images/mine/8yrg) | CryoEM structure of fospropofol-bound MRGPRX4-Gq complex | 分子名称: | Gs-mini-Gq chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Cao, C, Fay, J.F, Roth, B.L. | 登録日 | 2024-03-21 | 公開日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | 主引用文献 | MRGPRX4 mediates phospho-drug-associated pruritus in a humanized mouse model. Sci Transl Med, 16, 2024
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