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1R42
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Native Human Angiotensin Converting Enzyme-Related Carboxypeptidase (ACE2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ZINC ION, ...
著者Towler, P, Staker, B, Prasad, S.G, Menon, S, Ryan, D, Tang, J, Parsons, T, Fisher, M, Williams, D, Dales, N.A, Patane, M.A, Pantoliano, M.W.
登録日2003-10-07
公開日2004-02-03
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献ACE2 X-ray structures reveal a large hinge-bending motion important for inhibitor binding and catalysis.
J.Biol.Chem., 279, 2004
1R43
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Crystal structure of beta-alanine synthase from Saccharomyces kluyveri (selenomethionine substituted protein)
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-AMINO ISOBUTYRATE, ...
著者Lundgren, S, Gojkovic, Z, Piskur, J, Dobritzsch, D.
登録日2003-10-03
公開日2003-11-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Yeast beta-Alanine Synthase Shares a Structural Scaffold and Origin with Dizinc-dependent Exopeptidases
J.Biol.Chem., 278
1R44
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Crystal Structure of VanX
分子名称: D-alanyl-D-alanine dipeptidase, ZINC ION
著者Pratt, S.D, Katz, L, Severin, J.M, Holzman, T, Park, C.H.
登録日2003-10-03
公開日2004-06-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The Structure of VanX Reveals a Novel Amino-Dipeptidase Involved in Mediating Transposon-Based Vancomycin Resistance
Mol.Cell, 2, 1998
1R45
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ADP-ribosyltransferase C3bot2 from Clostridium botulinum, triclinic form
分子名称: GLYCEROL, Mono-ADP-ribosyltransferase C3, SULFATE ION
著者Teplyakov, A, Obmolova, G, Gilliland, G.L, Narumiya, S.
登録日2003-10-03
公開日2004-11-16
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Crystal structure of ADP-ribosyltransferase C3bot2 from Clostridium botulinum
To be Published
1R46
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Structure of human alpha-galactosidase
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Garman, S.C, Garboczi, D.N.
登録日2003-10-03
公開日2004-03-16
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献The molecular defect leading to Fabry disease: structure of human alpha-galactosidase
J.Mol.Biol., 337, 2004
1R47
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Structure of human alpha-galactosidase
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-galactosidase A, ...
著者Garman, S.C, Garboczi, D.N.
登録日2003-10-03
公開日2004-03-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献The molecular defect leading to Fabry disease: structure of human alpha-galactosidase
J.Mol.Biol., 337, 2004
1R48
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Solution structure of the C-terminal cytoplasmic domain residues 468-497 of Escherichia coli protein ProP
分子名称: Proline/betaine transporter
著者Zoetewey, D.L, Tripet, B.P, Kutateladze, T.G, Overduin, M.J, Wood, J.M, Hodges, R.S.
登録日2003-10-03
公開日2003-12-23
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution Structure of the C-terminal Antiparallel Coiled-coil Domain from Escherichia coli Osmosensor ProP.
J.Mol.Biol., 334, 2003
1R49
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Human topoisomerase I (Topo70) double mutant K532R/Y723F
分子名称: 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*TP*AP*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3', 5'-D(P*AP*AP*AP*AP*AP*TP*TP*TP*TP*TP*CP*TP*AP*AP*GP*TP*CP*TP*TP*TP*TP*T)-3', DNA topoisomerase I
著者Interthal, H, Quigley, P.M, Hol, W.G, Champoux, J.J.
登録日2003-10-03
公開日2003-12-16
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.13 Å)
主引用文献The role of lysine 532 in the catalytic mechanism of human topoisomerase I.
J.Biol.Chem., 279, 2004
1R4A
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Crystal Structure of GTP-bound ADP-ribosylation Factor Like Protein 1 (Arl1) and GRIP Domain of Golgin245 COMPLEX
分子名称: ADP-ribosylation factor-like protein 1, Golgi autoantigen, golgin subfamily A member 4, ...
著者Wu, M, Lu, L, Hong, W, Song, H.
登録日2003-10-04
公開日2004-01-13
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for recruitment of GRIP domain golgin-245 by small GTPase Arl1.
Nat.Struct.Mol.Biol., 11, 2004
1R4B
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ADP-ribosyltransferase C3bot2 from Clostridium botulinum, monoclinic form
分子名称: Mono-ADP-ribosyltransferase C3
著者Teplyakov, A, Obmolova, G, Gilliland, G.L, Narumiya, S.
登録日2003-10-04
公開日2004-11-16
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal Structure of ADP-RIBOSYLTRANSFERASE C3bot2 from CLOSTRIDIUM BOTULINUM
To be Published
1R4C
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N-Truncated Human Cystatin C; Dimeric Form With 3D Domain Swapping
分子名称: Cystatin C
著者Janowski, R, Abrahamson, M, Grubb, A, Jaskolski, M.
登録日2003-10-06
公開日2004-09-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Domain swapping in N-truncated human cystatin C.
J.Mol.Biol., 341, 2004
1R4D
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Solution structure of the chimeric L/D DNA oligonucleotide d(C8metGCGC(L)G(L)CGCG)2
分子名称: 5'-D(*CP*(8MG)P*CP*GP*(0DC)P*(0DG)P*CP*GP*CP*G)-3'
著者Cherrak, I, Mauffret, O, Santamaria, F, Rayner, B, Hocquet, A, Ghomi, M, Fermandjian, S.
登録日2003-10-06
公開日2003-10-21
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献L-nucleotides and 8-methylguanine of d(C1m8G2C3G4C5LG6LC7G8C9G10)2 act cooperatively to promote a left-handed helix under physiological salt conditions.
Nucleic Acids Res., 31, 2003
1R4E
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Solution structure of the Complex Formed between a Left-Handed Wedge-Shaped Spirocyclic Molecule and Bulged DNA
分子名称: 5'-D(*CP*AP*CP*GP*CP*AP*GP*TP*TP*CP*GP*GP*AP*C)-3', 5'-D(*GP*TP*CP*CP*GP*AP*TP*GP*CP*GP*TP*G)-3', SPIRO[NAPHTHALENE-2(3H),3'(10'H)-PENTALENO[1,2-B]NAPHTHALENE]-3,10'-DIONE, ...
著者Hwang, G.S, Jones, G.B, Goldberg, I.H.
登録日2003-10-06
公開日2004-04-27
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Stereochemical control of small molecule binding to bulged DNA: comparison of structures of spirocyclic enantiomer-bulged DNA complexes.
Biochemistry, 43, 2004
1R4F
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Inosine-Adenosine-Guanosine Preferring Nucleoside Hydrolase From Trypanosoma vivax: Trp260Ala Mutant In Complex With 3-Deaza-Adenosine
分子名称: 3-DEAZA-ADENOSINE, CALCIUM ION, IAG-nucleoside hydrolase
著者Versees, W, Loverix, S, Vandemeulebroucke, A, Geerlings, P, Steyaert, J.
登録日2003-10-06
公開日2004-04-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Leaving group activation by aromatic stacking: an alternative to general Acid catalysis.
J.Mol.Biol., 338, 2004
1R4G
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Solution structure of the Sendai virus protein X C-subdomain
分子名称: RNA polymerase alpha subunit
著者Blanchard, L, Tarbouriech, N, Blackledge, M, Timmins, P, Burmeister, W.P, Ruigrok, R.W, Marion, D.
登録日2003-10-06
公開日2004-03-09
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure and dynamics of the nucleocapsid-binding domain of the Sendai virus phosphoprotein in solution
Virology, 319, 2004
1R4H
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NMR Solution structure of the IIIc domain of GB Virus B IRES Element
分子名称: 5'-R(*GP*GP*GP*CP*AP*AP*GP*CP*CP*C)-3'
著者Kaluarachchi, K, Thiviyanathan, V, Rijinbrand, R, Lemon, S.M, Gorenstein, D.G.
登録日2003-10-06
公開日2004-10-19
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Mutational and structural analysis of stem-loop IIIC of the hepatitis C virus and GB virus B internal ribosome entry sites.
J.Mol.Biol., 343, 2004
1R4I
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Crystal Structure of Androgen Receptor DNA-Binding Domain Bound to a Direct Repeat Response Element
分子名称: 5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*TP*CP*AP*AP*GP*AP*AP*CP*AP*G)-3', 5'-D(*CP*TP*GP*TP*TP*CP*TP*TP*GP*AP*TP*GP*TP*TP*CP*TP*GP*G)-3', Androgen receptor, ...
著者Shaffer, P.L, Jivan, A, Dollins, D.E, Claessens, F, Gewirth, D.T.
登録日2003-10-06
公開日2004-06-29
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis of androgen receptor binding to selective androgen response elements.
Proc.Natl.Acad.Sci.USA, 101, 2004
1R4K
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Solution Structure of the Drosophila Argonaute 1 PAZ Domain
分子名称: Argonaute 1
著者Yan, K.S, Yan, S, Farooq, A, Han, A, Zeng, L, Zhou, M.-M.
登録日2003-10-07
公開日2003-12-09
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure and conserved RNA binding of the PAZ domain
Nature, 426, 2003
1R4L
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Inhibitor Bound Human Angiotensin Converting Enzyme-Related Carboxypeptidase (ACE2)
分子名称: (S,S)-2-{1-CARBOXY-2-[3-(3,5-DICHLORO-BENZYL)-3H-IMIDAZOL-4-YL]-ETHYLAMINO}-4-METHYL-PENTANOIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Towler, P, Staker, B, Prasad, S.G, Menon, S, Ryan, D, Tang, J, Parsons, T, Fisher, M, Williams, D, Dales, N.A, Patane, M.A, Pantoliano, M.W.
登録日2003-10-07
公開日2004-02-03
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献ACE2 X-ray structures reveal a large hinge-bending motion important for inhibitor binding and catalysis.
J.Biol.Chem., 279, 2004
1R4M
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APPBP1-UBA3-NEDD8, an E1-ubiquitin-like protein complex
分子名称: Ubiquitin-like protein NEDD8, ZINC ION, amyloid beta precursor protein-binding protein 1, ...
著者Walden, H, Podgorski, M.S, Holton, J.M, Schulman, B.A.
登録日2003-10-07
公開日2003-12-23
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1.
Mol.Cell, 12, 2003
1R4N
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APPBP1-UBA3-NEDD8, an E1-ubiquitin-like protein complex with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Ubiquitin-like protein NEDD8, ZINC ION, ...
著者Walden, H, Podgorski, M.S, Holton, J.M, Schulman, B.A.
登録日2003-10-07
公開日2003-12-23
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1.
Mol.Cell, 12, 2003
1R4O
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Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA
分子名称: 5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*TP*CP*GP*AP*TP*GP*TP*TP*CP*TP*G)-3', Glucocorticoid receptor, ZINC ION
著者Luisi, B.F, Xu, W.X, Otwinowski, Z, Freedman, L.P, Yamamoto, K.R, Sigler, P.B.
登録日2003-10-07
公開日2003-10-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystallographic Analysis of the Interaction of The Glucocorticoid Receptor with DNA
Nature, 352, 1991
1R4P
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Shiga toxin type 2
分子名称: 1,2-ETHANEDIOL, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, FORMIC ACID, ...
著者Fraser, M.E, Fujinaga, M, Cherney, M.M, Melton-Celsa, A.R, Twiddy, E.M, O'Brien, A.D, James, M.N.G.
登録日2003-10-07
公開日2004-05-11
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Structure of Shiga Toxin Type 2 (Stx2) from Escherichia coli O157:H7.
J.Biol.Chem., 279, 2004
1R4Q
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Shiga toxin
分子名称: SHT cytotoxin A subunit, Shigella toxin chain B
著者Fraser, M.E, Fujinaga, M, Cherney, M.M, Melton-Celsa, A.R, Twiddy, E.M, O'Brien, A.D, James, M.N.G.
登録日2003-10-07
公開日2004-05-11
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of Shiga Toxin Type 2 (Stx2) from Escherichia coli O157:H7.
J.Biol.Chem., 279, 2004
1R4R
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Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA
分子名称: 5'-D(*CP*TP*GP*AP*GP*AP*AP*CP*AP*TP*CP*AP*TP*GP*TP*TP*CP*TP*G)-3', 5'-D(*TP*CP*AP*GP*AP*AP*CP*AP*TP*GP*AP*TP*GP*TP*TP*CP*TP*CP*A)-3', Glucocorticoid receptor, ...
著者Luisi, B.F, Xu, W.X, Otwinowski, Z, Freedman, L.P, Yamamoto, K.R, Sigler, P.B.
登録日2003-10-07
公開日2003-10-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystallographic Analysis of the Interaction of the Glucocorticoid Receptor with DNA
Nature, 352, 1991

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