PDB: 184427 件ウェブページステータス検索Chemie searchBIRD

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6G8D	Crystal Structure of the Amyloid-like LNIYQY segment from the R1 repeat of the E. coli Biofilm-associated CsgA Curli protein 分子名称: Major curlin subunit 著者 Landau, M, Perov, S. 登録日 2018-04-08 公開日 2019-04-24 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural Insights into Curli CsgA Cross-beta Fibril Architecture Inspire Repurposing of Anti-amyloid Compounds as Anti-biofilm Agents. Plos Pathog., 15, 2019
6VNL	JAK2 JH1 in complex with SG3-179 分子名称: 4-[[4-[[3-(~{tert}-butylsulfonylamino)-4-chloranyl-phenyl]amino]-5-methyl-pyrimidin-2-yl]amino]-2-fluoranyl-~{N}-(1-methylpiperidin-4-yl)benzamide, Tyrosine-protein kinase JAK2 著者 Davis, R.R, Schonbrunn, E. 登録日 2020-01-29 公開日 2021-02-17 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural Insights into JAK2 Inhibition by Ruxolitinib, Fedratinib, and Derivatives Thereof. J.Med.Chem., 64, 2021
4E1D	Structure of a VgrG Vibrio cholerae toxin ACD domain in complex with ADP and Mn++ 分子名称: ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, SULFATE ION, ... 著者 Durand, E, Audoly, G, Derrez, E, Spinelli, S, Ortiz-Lombardia, M, Cascales, E, Raoult, D, Cambillau, C. 登録日 2012-03-06 公開日 2012-08-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Structure and functional characterization of the Vibrio cholerae toxin from the VgrG/MARTX family. J.Biol.Chem., 2012
6VNK	JAK2 JH1 in complex with PN4-073 分子名称: (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile, Tyrosine-protein kinase JAK2 著者 Davis, R.R, Schonbrunn, E. 登録日 2020-01-29 公開日 2021-02-17 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Insights into JAK2 Inhibition by Ruxolitinib, Fedratinib, and Derivatives Thereof. J.Med.Chem., 64, 2021
2ZNM	Oxidoreductase NmDsbA3 from Neisseria meningitidis 分子名称: Thiol:disulfide interchange protein DsbA 著者 Vivian, J.P, Scoullar, J, Robertson, A.L, Bottomley, S.P, Horne, J, Chin, Y, Velkov, T, Wielens, J, Thompson, P.E, Piek, S, Byres, E, Beddoe, T, Wilce, M.C.J, Kahler, C, Rossjohn, J, Scanlon, M.J. 登録日 2008-04-30 公開日 2008-08-19 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural and Biochemical Characterization of the Oxidoreductase NmDsbA3 from Neisseria meningitidis J.Biol.Chem., 283, 2008
2AQP	CU/ZN superoxide dismutase from neisseria meningitidis E73A mutant 分子名称: 1,2-ETHANEDIOL, COPPER (I) ION, Superoxide dismutase [Cu-Zn], ... 著者 DiDonato, M, Kassmann, C.J, Bruns, C.K, Cabelli, D.E, Cao, Z, Tabatabai, L.B, Kroll, J.S, Getzoff, E.D. 登録日 2005-08-18 公開日 2006-10-31 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 CU/ZN superoxide dismutase from neisseria meningitidis E73A mutant To be Published
6VS3	JAK2 JH1 in complex with BL2-057 分子名称: (3R)-3-cyclopentyl-3-[4-(2-{[4-(piperidin-4-yl)phenyl]amino}-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile, Tyrosine-protein kinase JAK2 著者 Davis, R.R, Schonbrunn, E. 登録日 2020-02-10 公開日 2021-02-17 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Insights into JAK2 Inhibition by Ruxolitinib, Fedratinib, and Derivatives Thereof. J.Med.Chem., 64, 2021
6GKS	X-ray structure determined from recombinant Charcot-Leyden crystal 分子名称: GLYCEROL, Galectin-10 著者 Verstraete, K, Verschueren, K, Savvides, S.N. 登録日 2018-05-21 公開日 2019-06-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Protein crystallization promotes type 2 immunity and is reversible by antibody treatment. Science, 364, 2019
8DXS	Cryo-EM structure of RBD-directed neutralizing antibody P2B4 in complex with prefusion SARS-CoV-2 spike glycoprotein 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, P2B4 Heavy chain, P2B4 Light chain, ... 著者 Reddem, E.R, Shapiro, L. 登録日 2022-08-03 公開日 2022-12-07 最終更新日 2023-01-18 実験手法 ELECTRON MICROSCOPY (3.76 Å) 主引用文献 Structural insights into broadly neutralizing antibodies elicited by hybrid immunity against SARS-CoV-2. Emerg Microbes Infect, 12, 2023
6G9G	Crystal Structure of the TASNSS segment from the R4-R5 loop of the E. coli Biofilm-associated CsgA Curli protein 分子名称: Major curlin subunit 著者 Landau, M, Perov, S. 登録日 2018-04-10 公開日 2019-04-24 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural Insights into Curli CsgA Cross-beta Fibril Architecture Inspire Repurposing of Anti-amyloid Compounds as Anti-biofilm Agents. Plos Pathog., 15, 2019
4PCN	Phosphotriesterase variant R22 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Phosphotriesterase variant PTE-R22, ZINC ION 著者 Jackson, C.J, Campbell, E, Kaltenbach, M, Tokuriki, N. 登録日 2014-04-16 公開日 2015-05-06 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 The role of protein dynamics in the evolution of new enzyme function. Nat. Chem. Biol., 12, 2016
8DW9	Crystal structure of neutralizing antibody D29 Fab in complex with SARS-CoV-2 spike receptor binding domain (RBD) 分子名称: D29 Fab light chain, D29 Heavy chain, Spike protein S1 著者 Reddem, E.R, Shapiro, L. 登録日 2022-08-01 公開日 2022-12-07 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Structural insights into broadly neutralizing antibodies elicited by hybrid immunity against SARS-CoV-2. Emerg Microbes Infect, 12, 2023
6VSN	JAK2 JH1 in complex with BL2-110 分子名称: (3S)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile, Tyrosine-protein kinase JAK2 著者 Davis, R.R, Schonbrunn, E. 登録日 2020-02-11 公開日 2021-02-17 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Insights into JAK2 Inhibition by Ruxolitinib, Fedratinib, and Derivatives Thereof. J.Med.Chem., 64, 2021
6GU7	CDK1/Cks2 in complex with AZD5438 分子名称: 4-(2-methyl-3-propan-2-yl-imidazol-4-yl)-~{N}-(4-methylsulfonylphenyl)pyrimidin-2-amine, Cyclin-dependent kinase 1, Cyclin-dependent kinases regulatory subunit 2 著者 Wood, D.J, Korolchuk, S, Tatum, N.J, Wang, L.Z, Endicott, J.A, Noble, M.E.M, Martin, M.P. 登録日 2018-06-19 公開日 2018-12-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Differences in the Conformational Energy Landscape of CDK1 and CDK2 Suggest a Mechanism for Achieving Selective CDK Inhibition. Cell Chem Biol, 26, 2019
6G7H	Retinal isomerization in bacteriorhodopsin revealed by a femtosecond X-ray laser: resting state structure 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL, Bacteriorhodopsin, ... 著者 Nogly, P, Weinert, T, James, D, Cabajo, S, Ozerov, D, Furrer, A, Gashi, D, Borin, V, Skopintsev, P, Jaeger, K, Nass, K, Bath, P, Bosman, R, Koglin, J, Seaberg, M, Lane, T, Kekilli, D, Bruenle, S, Tanaka, T, Wu, W, Milne, C, White, T, Barty, A, Weierstall, U, Panneels, V, Nango, E, Iwata, S, Hunter, M, Schapiro, I, Schertler, G, Neutze, R, Standfuss, J. 登録日 2018-04-06 公開日 2018-06-27 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser. Science, 361, 2018
5TF6	Structure and conformational plasticity of the U6 small nuclear ribonucleoprotein core 分子名称: CHLORIDE ION, GLYCEROL, POTASSIUM ION, ... 著者 Montemayor, E.J, Brow, D.A, Butcher, S.E. 登録日 2016-09-24 公開日 2017-01-11 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure and conformational plasticity of the U6 small nuclear ribonucleoprotein core. Acta Crystallogr D Struct Biol, 73, 2017
6G8C	Crystal Structure of the Amyloid-like IYQYGG segment from the R1 repeat of the E. coli Biofilm-associated CsgA Curli protein 分子名称: Major curlin subunit 著者 Landau, M, Perov, S. 登録日 2018-04-08 公開日 2019-04-24 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structural Insights into Curli CsgA Cross-beta Fibril Architecture Inspire Repurposing of Anti-amyloid Compounds as Anti-biofilm Agents. Plos Pathog., 15, 2019
6G8E	Crystal Structure of the Amyloid-like VTQVGF segment from the R5 repeat of the E. coli Biofilm-associated CsgA Curli protein 分子名称: Major curlin subunit 著者 Landau, M, Perov, S. 登録日 2018-04-08 公開日 2019-04-24 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural Insights into Curli CsgA Cross-beta Fibril Architecture Inspire Repurposing of Anti-amyloid Compounds as Anti-biofilm Agents. Plos Pathog., 15, 2019
6PYH	Cryo-EM structure of full-length IGF1R-IGF1 complex. Only the extracellular region of the complex is resolved. 分子名称: Insulin-like growth factor 1 receptor, Insulin-like growth factor I 著者 Li, J, Choi, E, Yu, H.T, Bai, X.C. 登録日 2019-07-29 公開日 2019-10-23 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Structural basis of the activation of type 1 insulin-like growth factor receptor. Nat Commun, 10, 2019
8E5W	Crystal structure of dehydroalanine Hip1 分子名称: DI(HYDROXYETHYL)ETHER, PALMITIC ACID, Protease, ... 著者 Goldfarb, N.E, Brooks, C.L, Ostrov, D.A. 登録日 2022-08-22 公開日 2022-12-07 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 2.1 angstrom crystal structure of the Mycobacterium tuberculosis serine hydrolase, Hip1, in its anhydro-form (Anhydrohip1). Biochem.Biophys.Res.Commun., 630, 2022
3ZD2	THE STRUCTURE OF THE TWO N-TERMINAL DOMAINS OF COMPLEMENT FACTOR H RELATED PROTEIN 1 SHOWS FORMATION OF A NOVEL DIMERISATION INTERFACE 分子名称: 1,2-ETHANEDIOL, COMPLEMENT FACTOR H-RELATED PROTEIN 1 著者 Caesar, J.J.E, Goicoechea de Jorge, E, Pickering, M.C, Lea, S.M. 登録日 2012-11-23 公開日 2013-03-13 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Dimerization of Complement Factor H-Related Proteins Modulates Complement Activation in Vivo. Proc.Natl.Acad.Sci.USA, 110, 2013
8EBO	Homopurine parallel G-quadruplex from human chromosome 7 stabilized by K+ ions 分子名称: COBALT (III) ION, DNA (5'-D(*GP*AP*GP*GP*GP*AP*GP*GP*GP*AP*GP*GP*GP*AP*AP*AP*AP*GP*GP*GP*GP*A)-3'), N-METHYLMESOPORPHYRIN, ... 著者 Chen, E.V, Yatsunyk, L.A. 登録日 2022-08-31 公開日 2022-12-28 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Homopurine guanine-rich sequences in complex with N-methyl mesoporphyrin IX form parallel G-quadruplex dimers and display a unique symmetry tetrad. Bioorg.Med.Chem., 77, 2022
3ZYX	Crystal structure of human monoamine oxidase B in complex with methylene blue and bearing the double mutation I199A-Y326A 分子名称: 3,7-BIS(DIMETHYLAMINO)PHENOTHIAZIN-5-IUM, AMINE OXIDASE [FLAVIN-CONTAINING] B, FLAVIN-ADENINE DINUCLEOTIDE 著者 Milczek, E.M, Binda, C, Rovida, S, Mattevi, A, Edmondson, D.E. 登録日 2011-08-29 公開日 2011-12-14 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The 'Gating' Residues Ile199 and Tyr326 in Human Monoamine Oxidase B Function in Substrate and Inhibitor Recognition. FEBS J., 278, 2011
7LU5	SAMHD1(113-626) H206R D207N R366H 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 著者 Temple, J.T, Bowen, N.E. 登録日 2021-02-20 公開日 2021-11-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.57 Å) 主引用文献 Structural and functional characterization explains loss of dNTPase activity of the cancer-specific R366C/H mutant SAMHD1 proteins. J.Biol.Chem., 297, 2021
7LTW	Crystal structure of the mouse Kirrel2 D1 homodimer 分子名称: Kin of IRRE-like protein 2, SODIUM ION 著者 Roman, C.A, Pak, J.S, Wang, J, Ozkan, E. 登録日 2021-02-20 公開日 2021-11-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Molecular and structural basis of olfactory sensory neuron axon coalescence by Kirrel receptors. Cell Rep, 37, 2021

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