PDB: 5434 件ウェブページステータス検索Chemie searchBIRD

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1AWT	SECYPA COMPLEXED WITH HAGPIA 分子名称: CYCLOPHILIN A, PEPTIDE FROM THE HIV-1 CAPSID PROTEIN 著者 Vajdos, F.F. 登録日 1997-10-05 公開日 1998-03-18 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Crystal structure of cyclophilin A complexed with a binding site peptide from the HIV-1 capsid protein. Protein Sci., 6, 1997
1WJP	Solution structure of zf-C2H2 domains from human Zinc finger protein 295 分子名称: ZINC ION, Zinc finger protein 295 著者 Tomizawa, T, Kigawa, T, Saito, K, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2004-05-29 公開日 2004-11-29 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of zf-C2H2 domains from human Zinc finger protein 295 To be Published
1X4D	Solution structure of RRM domain in Matrin 3 分子名称: Matrin 3 著者 He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-05-14 公開日 2005-11-14 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of RRM domain in Matrin 3 To be Published
1BT6	P11 (S100A10), LIGAND OF ANNEXIN II IN COMPLEX WITH ANNEXIN II N-TERMINUS 分子名称: ANNEXIN II, S100A10 著者 Rety, S, Sopkova, J, Renouard, M, Osterloh, D, Gerke, V, Russo-Marie, F, Lewit-Bentley, A. 登録日 1998-09-02 公開日 1999-01-27 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The crystal structure of a complex of p11 with the annexin II N-terminal peptide. Nat.Struct.Biol., 6, 1999
1WWQ	Solution Structure of Mouse ER 分子名称: Enhancer of rudimentary homolog 著者 Li, H, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-01-12 公開日 2006-01-03 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the mouse enhancer of rudimentary protein reveals a novel fold J.Biomol.Nmr, 32, 2005
5TLH	Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with the inhibitor 2-naphthol 6-bisphosphonate 分子名称: Fructose-bisphosphate aldolase A, GLYCEROL, METHYLENEDIPHOSPHONIC ACID, ... 著者 Heron, P.W, Sygusch, J. 登録日 2016-10-11 公開日 2017-10-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.204 Å) 主引用文献 Bisphosphonate Inhibitors of Mammalian Glycolytic Aldolase. J.Med.Chem., 61, 2018
1WE7	Solution structure of Ubiquitin-like domain in SF3a120 分子名称: Sf3a1 protein 著者 He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2004-05-24 公開日 2004-11-24 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of Ubiquitin-like domain in SF3a120 To be Published
5TD9	Structure of Human Enolase 2 分子名称: CHLORIDE ION, Gamma-enolase, MAGNESIUM ION 著者 Leonard, P.G, Muller, F.L. 登録日 2016-09-19 公開日 2017-09-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.318 Å) 主引用文献 Pomhex, a cell-permeable Enolase inhibitor for Collateral Lethality targeting of ENO1-deleted Glioblastoma To Be Published
5TI3	CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH INHIBITOR 17503468 分子名称: 1,2-ETHANEDIOL, 2,5-dibromo-N-[3-(2-oxopyrrolidin-1-yl)phenyl]benzene-1-sulfonamide, Bromodomain-containing protein 4 著者 Zhu, J.-Y, Ember, S.W.J, SCHONBRUNN, E. 登録日 2016-09-30 公開日 2017-08-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.703 Å) 主引用文献 Identification of a Novel Class of BRD4 Inhibitors by Computational Screening and Binding Simulations. ACS Omega, 2, 2017
5TI2	CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH INHIBITOR 7635936 分子名称: 1,2-ETHANEDIOL, 3-fluoro-N-[3-(2-oxopyrrolidin-1-yl)phenyl]benzene-1-sulfonamide, Bromodomain-containing protein 4 著者 Zhu, J.-Y, Ember, S.W.J, SCHONBRUNN, E. 登録日 2016-09-30 公開日 2017-08-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Identification of a Novel Class of BRD4 Inhibitors by Computational Screening and Binding Simulations. ACS Omega, 2, 2017
5TI7	CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH INHIBITOR 17528462 分子名称: 1,2-ETHANEDIOL, 5-bromo-2-methoxy-N-(3-(2-oxopyrrolidin-1-yl)phenyl)benzenesulfonamide, Bromodomain-containing protein 4 著者 Zhu, J.-Y, Ember, S.W.J, Schonbrunn, E. 登録日 2016-10-01 公開日 2017-08-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Identification of a Novel Class of BRD4 Inhibitors by Computational Screening and Binding Simulations. ACS Omega, 2, 2017
5TLE	Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with the inhibitor 2-phosphate-naphthalene 6-bisphosphonate 分子名称: Fructose-bisphosphate aldolase A, GLYCEROL, {[6-(phosphonooxy)naphthalen-2-yl]methylene}bis(phosphonic acid) 著者 Heron, P.W, Sygusch, J. 登録日 2016-10-11 公開日 2017-10-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.576 Å) 主引用文献 Bisphosphonate Inhibitors of Mammalian Glycolytic Aldolase. J.Med.Chem., 61, 2018
8DKB	Crystal Structure of human YEATS4 in complex with Pfizer small molecule compound 3b 分子名称: N-ethyl-1-{(3S,4S)-1-[(1-hydroxycyclohexyl)methyl]-3-methylpiperidin-4-yl}-2-methyl-1H-benzimidazole-5-carboxamide, YEATS domain-containing protein 4 著者 Dias, J.M, Byrnes, L.J, Varghese, A.H. 登録日 2022-07-05 公開日 2023-01-11 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Discovery of High-Affinity Small-Molecule Binders of the Epigenetic Reader YEATS4. J.Med.Chem., 66, 2023
5TIJ	Structure of Human Enolase 2 with ((3S,5S)-1,5-dihydroxy-3-methyl-2-oxopyrrolidin-3-yl)phosphonate (purified enantiomer) 分子名称: ((3S,5S)-1,5-dihydroxy-3-methyl-2-oxopyrrolidin-3-yl)phosphonic acid, Gamma-enolase, MAGNESIUM ION 著者 Leonard, P.G, Muller, F.L. 登録日 2016-10-03 公開日 2017-10-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.634 Å) 主引用文献 Eradication of ENO1-deleted Glioblastoma through Collateral Lethality Biorxiv, 2019
1WM2	Crystal structure of human SUMO-2 protein 分子名称: Ubiquitin-like protein SMT3B 著者 Huang, W.-C, Ko, T.-P, Li, S.S.-L, Wang, A.H.-J. 登録日 2004-07-02 公開日 2004-11-30 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structures of the human SUMO-2 protein at 1.6 A and 1.2 A resolution: implication on the functional differences of SUMO proteins Eur.J.Biochem., 271, 2004
1WF0	Solution structure of RRM domain in TAR DNA-binding protein-43 分子名称: TAR DNA-binding protein-43 著者 He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2004-05-25 公開日 2004-11-25 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of RRM domain in TAR DNA-binding protein-43 To be Published
1WIB	Solution structure of the N-terminal domain from mouse hypothetical protein BAB22488 分子名称: 60S ribosomal protein L12 著者 Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2004-05-28 公開日 2004-11-28 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the N-terminal domain from mouse hypothetical protein BAB22488 To be Published
1WTB	Complex structure of the C-terminal RNA-binding domain of hnRNP D (AUF1) with telomere DNA 分子名称: 5'-D(P*TP*AP*GP*G)-3', Heterogeneous nuclear ribonucleoprotein D0 著者 Enokizono, Y, Konishi, Y, Nagata, K, Ouhashi, K, Uesugi, S, Ishikawa, F, Katahira, M. 登録日 2004-11-22 公開日 2005-04-05 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Structure of hnRNP D complexed with single-stranded telomere DNA and unfolding of the quadruplex by heterogeneous nuclear ribonucleoprotein D J.Biol.Chem., 280, 2005
1WIZ	Solution structure of the first CUT domain of KIAA1034 protein 分子名称: DNA-binding protein SATB2 著者 Inoue, K, Nameki, S, Hayashi, F, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2004-05-28 公開日 2004-11-28 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the first CUT domain of KIAA1034 protein To be Published
5U28	BRD4 first bromodomain (BD1) in complex with dual PI3 kinase inhibitor SF2523 分子名称: 3-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(morpholin-4-yl)-7H-thieno[3,2-b]pyran-7-one, Bromodomain-containing protein 4, DI(HYDROXYETHYL)ETHER, ... 著者 Andrews, F.H, Kutateladze, T.G. 登録日 2016-11-30 公開日 2017-02-08 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.798 Å) 主引用文献 Dual-activity PI3K-BRD4 inhibitor for the orthogonal inhibition of MYC to block tumor growth and metastasis. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1WHW	Solution structure of the N-terminal RNA binding domain from hypothetical protein BAB23448 分子名称: hypothetical protein RIKEN CDNA 1200009A02 著者 Nagata, T, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2004-05-28 公開日 2004-11-28 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the N-terminal RNA binding domain from hypothetical protein BAB23448 To be Published
8DEY	Ternary complex structure of Cereblon-DDB1 bound to IKZF2(ZF2,3) and the molecular glue DKY709 分子名称: (3S)-3-[5-(1-benzylpiperidin-4-yl)-1-oxo-1,3-dihydro-2H-isoindol-2-yl]piperidine-2,6-dione, DNA damage-binding protein 1, Protein cereblon, ... 著者 Ma, X, Ornelas, E, Clifton, M.C. 登録日 2022-06-21 公開日 2023-03-08 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 Discovery and characterization of a selective IKZF2 glue degrader for cancer immunotherapy. Cell Chem Biol, 30, 2023
5U2F	BRD4 first bromodomain (BD1) in complex with dual PI3 kinase (PI3K) inhibitor SF2558HA 分子名称: Bromodomain-containing protein 4, N-hydroxy-4-[5-(morpholin-4-yl)-7-oxo-7H-thieno[3,2-b]pyran-3-yl]benzamide 著者 Andrews, F.H, Kutateladze, T.G. 登録日 2016-11-30 公開日 2017-02-08 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.525 Å) 主引用文献 Dual-activity PI3K-BRD4 inhibitor for the orthogonal inhibition of MYC to block tumor growth and metastasis. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
8CUC	Crystal structure analysis of SALL4 zinc finger domain in complex with DNA 分子名称: DNA (5'-D(P*CP*GP*AP*AP*AP*TP*AP*TP*TP*AP*GP*C)-3'), DNA (5'-D(P*GP*CP*TP*AP*AP*TP*AP*TP*TP*TP*CP*G)-3'), Sal-like protein 4, ... 著者 Seo, H.S, Dhe-Paganon, S. 登録日 2022-05-17 公開日 2023-05-24 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Crystal Structure Analysis of SALL4 Zinc Finger domain in complex with DNA To Be Published
8CV5	Peptide 4.2B in complex with BRD3.2 分子名称: ACETYL GROUP, AMINO GROUP, Bromodomain-containing protein 3, ... 著者 Franck, C, Mackay, J.P. 登録日 2022-05-18 公開日 2023-05-24 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Discovery and characterization of cyclic peptides selective for the C-terminal bromodomains of BET family proteins. Structure, 31, 2023

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